Sugi Predict

Sugi Predict / Compounds / SCHEMBL179779

SCHEMBL179779

SCHEMBL179779

CCN1c2ccccc2Sc2c(C(=O)O)cccc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 9/20 0.50
▸ ALDH1A1 P00352 6/20 0.50
▸ HTT P42858 3/20 0.50
▸ HPGD P15428 2/20 0.50
▸ MEN1 O00255 7/20 0.47
▸ KMT2A Q03164 7/20 0.47
▸ USP2 O75604 3/20 0.47
▸ CRHBP P24387 2/20 0.47
▸ CRHR2 Q13324 2/20 0.47
▸ IDE P14735 1/20 0.47
▸ LMNA P02545 2/20 0.47
▸ POLB P06746 3/20 0.46
▸ THRB P10828 1/20 0.44
▸ GAA P10253 2/20 0.44
▸ RAB9A P51151 3/20 0.43
▸ KDM4E B2RXH2 1/20 0.43
▸ TP53 P04637 1/20 0.43
▸ ALOX15 P16050 1/20 0.43
▸ ALOX12 P18054 1/20 0.43
▸ CASP1 P29466 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30184237 1.00 MAPT (0.50) MAPTALDH1A1HTTHPGDMEN1
SCHEMBL6262710 0.83 MEN1 (0.71) MAPTALDH1A1HTTMEN1KMT2A
SCHEMBL628325 0.81 MAOA (0.55) MAPTALDH1A1MEN1KMT2ALMNA
SCHEMBL6263203 0.80 MAPT (0.47) MAPTALDH1A1HTTHPGDMEN1
SCHEMBL6262674 0.79 MEN1 (0.52) MAPTALDH1A1HTTHPGDMEN1
SCHEMBL6262678 0.79 ALDH1A1 (0.46) MAPTALDH1A1HTTHPGDMEN1
Propionic Acid SCHEMBL8502344 0.79 MEN1 (0.63) MAPTALDH1A1HTTHPGDMEN1
SCHEMBL9712163 0.77 ALDH1A1 (0.46) MAPTALDH1A1HTTHPGDMEN1
SCHEMBL29557425 0.76 KDM1A (0.61) MAPTALDH1A1HTTHPGDKMT2A
SCHEMBL293951 0.76 KDM1A (0.61) MAPTALDH1A1HTTHPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 747 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070261806-A1 Treatment of Pulp Stocks Using Oxidative Enzymes to Reduce Pitch Deposition ENZYMATIC DEINKING TECHNOLOGIES, LLC 2007-11-15 — — US claimed
EP-0707637-B1 ENHANCEMENT OF LACCASE REACTIONS NOVOZYMES AS (DK) 2005-11-02 — — EP claimed
EP-1137391-B1 METHOD FOR TREATING HAIR NOVOZYMES AS (DK) 2004-11-03 — — EP claimed
US-20040049859-A1 Enzyme composition for bleaching human keratinous fibres and bleaching method L'OREAL S.A. (FR) 2004-03-18 — — US claimed
US-20040025265-A1 Enzyme composition for bleaching human keratinous fibres and bleaching method LANG GERARD (FR) 2004-02-12 — — US claimed
CN-1443060-A Enzyme-based composition and process for bleaching human keratin fibers OREAL (FR) 2003-09-17 — — CN claimed
US-20030159706-A1 Enzyme composition for bleaching human keratinous fibres and bleaching method L'OREAL S.A. (FR) 2003-08-28 — — US claimed
US-6572843-B1 Combining permanent dyeing and straightening; applying to reduced hair an oxidizing enzyme (Laccase), a mediator, and a chemical oxidizing agent that produces hydrogen peroxide NOVOZYMES, A/S (DK) 2003-06-03 — — US claimed
US-20020119136-A1 Antimicrobial peroxidase compositions NOVOZYMES A/S (DK) 2002-08-29 — — US claimed
US-20020007524-A1 Contacting fibers in a dry state with an oxidoreductase and a dye precursor; reduced hair damage NOVOZYMES A/S (DK) 2002-01-24 — — US claimed
WO-1997030143-A1 CELLULASE ACTIVITY CONTROL BY A TERMINATOR THE PROCTER & GAMBLE COMPANY (US) 1997-08-21 — — WO claimed
CN-1149314-A Dye-stransfer inhibitory preparation, and detergent composition comprising such a preparation NOVO NORDISK AS (DK) 1997-05-07 — — CN claimed
EP-0763094-A1 DYE-TRANSFER INHIBITORY PREPARATION, AND DETERGENT COMPOSITION COMPRISING SUCH A PREPARATION NOVO NORDISK A/S (DK) 1997-03-19 — — EP claimed
CN-1126490-A Enhancement of laccase reactions NOVO NORDISK AS (DK) 1996-07-10 — — CN claimed
EP-0707637-A1 ENHANCEMENT OF LACCASE REACTIONS NOVO NORDISK A/S (DK) 1996-04-24 — — EP claimed
WO-1996006930-A1 COPRINACEAE LACCASES NOVO NORDISK A/S (DK) 1996-03-07 — — WO claimed
WO-1995033039-A1 DYE-TRANSFER INHIBITORY PREPARATION, AND DETERGENT COMPOSITION COMPRISING SUCH A PREPARATION NOVO NORDISK A/S (DK) 1995-12-07 — — WO claimed
EP-0679183-A1 ENHANCEMENT OF ENZYME REACTIONS NOVO NORDISK A/S (DK) 1995-11-02 — — EP claimed
WO-1995001426-A1 ENHANCEMENT OF LACCASE REACTIONS NOVO NORDISK A/S (DK) 1995-01-12 — — WO claimed
WO-1994012621-A1 ENHANCEMENT OF ENZYME REACTIONS NOVO NORDISK (DK) 1994-06-09 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030159706-A1 Enzyme composition for bleaching human keratinous fibres and bleaching method KRT18, LPO, MPO MAPT 1208/4885ALDH1A1 347/4885HTT 2951/4885
US-20020007524-A1 Contacting fibers in a dry state with an oxidoreductase and a dye precursor; reduced hair damage KRT18, CYB5R3, ADH7 MAPT 2112/4885ALDH1A1 169/4885HTT 3724/4885
US-20040025265-A1 Enzyme composition for bleaching human keratinous fibres and bleaching method KRT18, LPO, ALDH1A2 MAPT 1295/4885ALDH1A1 494/4885HTT 2321/4885
US-20040049859-A1 Enzyme composition for bleaching human keratinous fibres and bleaching method KRT18, COXFA4, LPO MAPT 1092/4885ALDH1A1 322/4885HTT 2071/4885
US-20020119136-A1 Antimicrobial peroxidase compositions LPO, MPO, GPX4 MAPT 4153/4885ALDH1A1 236/4885HTT 2880/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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