SCHEMBL17995378

SCHEMBL17995378

c1ccc(-c2ccc(N(c3ccc4c(c3)C(c3ccccc3)(c3ccccc3)c3ccccc3-4)c3ccc4c5ccccc5c5ccccc5c4c3)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
OPRK1 P41145 1/20 0.36
KMT2A Q03164 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
PDK2 Q15119 3/20 0.35
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21923878 0.97 PDK2 (0.34) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL21392523 0.96 PDK2 (0.37) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL21392520 0.95 PDK2 (0.36) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL19218678 0.95 PDK2 (0.36) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL24029545 0.94 KDM4E (0.35) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL21124230 0.94 KDM4E (0.35) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL19218740 0.94 KDM4E (0.35) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL17903151 0.93 MEN1 (0.41) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL19218218 0.93 PDK2 (0.38) MEN1LMNAMAPTKMT2ASMN1; SMN2
SCHEMBL20707548 0.93 KDM4E (0.38) KDM4EMEN1LMNAMAPTOPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1088 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12048237-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-23 US disclosed
US-20240244955-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-18 US disclosed
US-20240244955-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-18 US disclosed
EP-4401530-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2024-07-17 EP disclosed
EP-3816175-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2024-07-17 EP disclosed
US-12041846-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-16 US disclosed
US-12041846-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-16 US disclosed
US-12035613-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-09 US disclosed
US-12035614-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-09 US disclosed
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 US disclosed
US-20160240799-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-08-18 US disclosed
US-20160240800-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-08-18 US disclosed
US-20160240800-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-08-18 US disclosed
US-20160240792-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-08-18 US disclosed
US-20160240799-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-08-18 US disclosed
EP-3056504-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2016-08-17 EP disclosed
US-20160233436-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-08-11 US disclosed
US-20160233429-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-08-11 US disclosed
US-20160233436-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-08-11 US disclosed
US-20160233429-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-08-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160233436-A1 Organic Electroluminescent Materials and Devices OCIAD1, OCIAD2, OPRD1 KDM4E 2617/4885MEN1 4467/4885LMNA 4402/4885
US-20240244955-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES AOX1, SBDS, OCIAD2 KDM4E 3812/4885MEN1 4468/4885LMNA 744/4885
US-12041846-B2 Organic electroluminescent materials and devices OCIAD1, OSBP, OCIAD2 KDM4E 4079/4885MEN1 2780/4885LMNA 2866/4885
US-20160240792-A1 Organic Electroluminescent Materials and Devices CBX2, DDX3X, CBX7 KDM4E 1842/4885MEN1 2251/4885LMNA 3089/4885
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ICOSLG KDM4E 3179/4885MEN1 3094/4885LMNA 2246/4885
US-12048237-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OSBP KDM4E 3316/4885MEN1 4039/4885LMNA 4519/4885
US-20160233429-A1 Organic Electroluminescent Materials and Devices NBAS, TBCB, SLC1A2 KDM4E 3740/4885MEN1 1915/4885LMNA 3776/4885
US-12035614-B2 Organic electroluminescent materials and devices ZFR, SOD1, NDUFS2 KDM4E 3027/4885MEN1 3907/4885LMNA 4451/4885
US-20160240799-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP2 KDM4E 4105/4885MEN1 1367/4885LMNA 3201/4885
US-12035613-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OTC KDM4E 1544/4885MEN1 2207/4885LMNA 3061/4885
US-20160240800-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OXER1, TECR, OR10J3 KDM4E 1869/4885MEN1 3296/4885LMNA 2673/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.