Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 6/20 | 0.45 |
| ▸ | GUSB | P08236 | 2/20 | 0.45 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | F2R | P25116 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 3/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA3 | P07451 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA6 | P23280 | 2/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1802857 | 0.88 | CXCR3 (0.57) | CTSDGUSBCXCR3NPSR1SMN1; SMN2 | |
| SCHEMBL1802357 | 0.85 | F2R (0.41) | CTSDGUSBCXCR3NPSR1SMN1; SMN2 | |
| SCHEMBL1800064 | 0.85 | CTSD (0.46) | CTSDCXCR3NPSR1SMN1; SMN2KDM4E | |
| SCHEMBL1802569 | 0.81 | SMN1; SMN2 (0.50) | CTSDGUSBCXCR3NPSR1SMN1; SMN2 | |
| SCHEMBL1803118 | 0.81 | MAPT (0.59) | CTSDNPSR1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL5040634 | 0.75 | KDM4E (0.66) | SMN1; SMN2KDM4EALDH1A1HTTTSHR | |
| SCHEMBL5000979 | 0.70 | SMN1; SMN2 (0.45) | CTSDGUSBCXCR3NPSR1SMN1; SMN2 | |
| SCHEMBL1801438 | 0.68 | SMN1; SMN2 (0.49) | CTSDCXCR3NPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4996791 | 0.67 | CXCR3 (0.57) | CTSDGUSBCXCR3NPSR1SMN1; SMN2 | |
| SCHEMBL2581813 | 0.65 | KDM4E (0.68) | SMN1; SMN2KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7951957-B2 | Substituted benzimidazoles and their use for inducing apoptosis | BASILEA PHARMACEUTICA AG (CH) | 2011-05-31 | — | — | US | claimed |