Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | NQO2 | P16083 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.46 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | CCND1 | P24385 | 1/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | GPR3 | P46089 | 1/20 | 0.44 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29576413 | 1.00 | ALDH1A1 (0.59) | ALDH1A1MAPTKDM4ERXFP1NQO2 | |
| Hydrochloric Acid SCHEMBL29744398 | 0.98 | ALDH1A1 (0.57) | ALDH1A1MAPTKDM4ERXFP1NQO2 | |
| Iodide SCHEMBL27839552 | 0.98 | ALDH1A1 (0.57) | ALDH1A1MAPTKDM4ERXFP1NQO2 | |
| SCHEMBL16463000 | 0.77 | BIRC5 (0.42) | ALDH1A1MAPTKDM4ERXFP1NQO2 | |
| SCHEMBL19810738 | 0.76 | MAPK1 (0.40) | ALDH1A1KDM4ENQO2HPGDGPR3 | |
| SCHEMBL8579432 | 0.76 | MAPK1 (0.40) | ALDH1A1KDM4ENQO2HPGDGPR3 | |
| SCHEMBL8653902 | 0.75 | PDE5A (0.47) | ALDH1A1KDM4E | |
| SCHEMBL5810173 | 0.74 | SMN1; SMN2 (0.39) | ALDH1A1KDM4ENQO2HPGDGPR3 | |
| SCHEMBL6667748 | 0.74 | ERCC1 (0.44) | ALDH1A1KDM4EHPGDERCC1FEN1 | |
| SCHEMBL9522423 | 0.74 | MAPT (1.00) | ALDH1A1MAPTKDM4ERXFP1NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3414229-A1 | QUINOLINONE LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | Pharmakea, Inc. (US) | 2018-12-19 | — | — | EP | claimed |
| WO-2017139274-A1 | QUINOLINONE LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | PHARMAKEA, INC. (US) | 2017-08-17 | — | — | WO | claimed |
| EP-2734514-B1 | USE OF A THIOPHENE COMPOUND AS A MATRIX IN THE SPECIFIC DETECTION, IDENTIFICATION AND/OR QUANTIFICATION OF ALKALOIDS BY MALDI-TOF MASS SPECTROMETRY | UNIV ANGERS (FR) | 2015-07-08 | — | — | EP | claimed |
| US-9051296-B2 | Aryl carboxamide derivatives as TTX-S blockers | RAQUALIA PHARMA INC. (JP) | 2015-06-09 | — | — | US | claimed |
| US-20140319331-A1 | NEW USE FOR A COMPOUND AS A MATRIX IN THE SPECIFIC DETECTION, IDENTIFICATION AND/OR QUANTIFICATION OF ALKALOIDS BY MALDI-TOF MASS SPECTROMETRY | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS (FR) | 2014-10-30 | — | — | US | claimed |
| US-20120232052-A1 | ARYL CARBOXAMIDE DERIVATIVES AS TTX-S BLOCKERS | RAQUALIA PHARMA INC. (JP) | 2012-09-13 | — | — | US | claimed |
| WO-2011058766-A1 | ARYL CARBOXAMIDE DERIVATIVES AS TTX-S BLOCKERS | RAQUALIA PHARMA INC. (JP) | 2011-05-19 | — | — | WO | claimed |
| EP-1434585-A1 | ALKYNE MATRIX METALLOPROTEINASE INHIBITORS | Warner-Lambert Company LLC (US) | 2004-07-07 | — | — | EP | claimed |
| WO-2003032999-A1 | ALKYNE MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2003-04-24 | — | — | WO | claimed |
| US-12344606-B2 | Next-generation modulators of stimulator of interferon genes (STING) | Ryvu Therapeutics S.A. (PL) | 2025-07-01 | — | — | US | disclosed |
| CN-117137977-A | Preparation method of lactation-promoting traditional Chinese medicine composition for sows | 北京中农劲腾生物制药股份有限公司 | 2023-12-01 | — | — | CN | disclosed |
| US-20230382910-A1 | HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN | VERTEX PHARMACEUTICALS INCORPORATED | 2023-11-30 | — | — | US | disclosed |
| US-20220251082-A1 | NEXT-GENERATION MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) | Ryvu Therapeutics S.A. (PL) | 2022-08-11 | — | — | US | disclosed |
| US-20220127266-A1 | MALIC ENZYME INHIBITORS | SUN PHARMA ADVANCED RESEARCH COMPANY LTD (IN) | 2022-04-28 | — | — | US | disclosed |
| US-4772614-A | QUINOLINOLS | THE BOOTS COMPANY (GB) | 1988-09-20 | — | — | US | disclosed |
| EP-0282365-A1 | 1-Dethia-2-thia-cephalosporanic-acid derivatives, process for their preparation, their use as therapeutic agents and pharmaceutical compositions containing them | ROUSSEL-UCLAF (FR) | 1988-09-14 | — | — | EP | disclosed |
| CN-86104611-A | The preparation method of therapeutical agent | — | 1988-01-27 | — | — | CN | disclosed |
| EP-0206616-A2 | Quinolones having antihypertensive activity | The Boots Company PLC (GB) | 1986-12-30 | — | — | EP | disclosed |
| US-4443465-A | Aldose reductase inhibitory pyrrole derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-04-17 | — | — | US | disclosed |
| EP-0065393-A1 | Pyrrole derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-11-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220251082-A1 | NEXT-GENERATION MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) | STING1, IRF3, CGAS | ALDH1A1 4562/4885MAPT 1537/4885KDM4E 4160/4885 |
| US-12344606-B2 | Next-generation modulators of stimulator of interferon genes (STING) | STING1, IRF3, CGAS | ALDH1A1 4562/4885MAPT 1537/4885KDM4E 4160/4885 |
| US-20140319331-A1 | NEW USE FOR A COMPOUND AS A MATRIX IN THE SPECIFIC DETECTION, IDENTIFICATION AND/OR QUANTIFICATION OF ALKALOIDS BY MALDI-TOF MASS SPECTROMETRY | CIAPIN1, SRMS, MMP7 | ALDH1A1 3584/4885MAPT 1270/4885KDM4E 4147/4885 |
| US-20220127266-A1 | MALIC ENZYME INHIBITORS | ME1, ME2, ME3 | ALDH1A1 144/4885MAPT 2817/4885KDM4E 1301/4885 |
| US-20230382910-A1 | HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN | TRPV1, SCN3A, KCNN3 | ALDH1A1 1762/4885MAPT 2089/4885KDM4E 4346/4885 |
| US-20120232052-A1 | ARYL CARBOXAMIDE DERIVATIVES AS TTX-S BLOCKERS | SCN1B, SCN1A, SCN2B | ALDH1A1 787/4885MAPT 4090/4885KDM4E 1141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.