Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Di(Hydroxyethyl)Ether. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.38 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 6/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.38 |
| ▸ | PPARG | P37231 | 6/20 | 0.38 |
| ▸ | PPARD | Q03181 | 6/20 | 0.38 |
| ▸ | PPARA | Q07869 | 6/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Di(Hydroxyethyl)Ether SCHEMBL29707582 | 1.00 | FFAR3 (0.56) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Di(Hydroxyethyl)Ether SCHEMBL1362182 | 0.96 | FFAR3 (0.62) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Triethylene Glycol SCHEMBL3693562 | 0.93 | FFAR3 (0.59) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Hexaethylene Glycol SCHEMBL10954529 | 0.93 | FFAR3 (0.59) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Triethylene Glycol SCHEMBL5897768 | 0.93 | FFAR3 (0.59) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Tetraethylene Glycol SCHEMBL28861486 | 0.93 | FFAR3 (0.59) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Di(Hydroxyethyl)Ether SCHEMBL181704 | 0.91 | FFAR3 (0.56) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Triethylene Glycol SCHEMBL2456505 | 0.89 | FFAR3 (0.54) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Diethylene Glycol Monoethyl Ether SCHEMBL28088918 | 0.88 | ALDH1A1 (0.56) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL28088947 | 0.87 | ALDH1A1 (0.61) | FFAR3HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 255 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12637578-B2 | Ink jet ink composition and recording method | SEIKO EPSON CORPORATION (JP) | 2026-05-26 | — | — | US | disclosed |
| US-12637804-B2 | Ink jet recording method | SEIKO EPSON CORPORATION (JP) | 2026-05-26 | — | — | US | disclosed |
| US-12630973-B2 | Recording method | SEIKO EPSON CORPORATION (JP) | 2026-05-19 | — | — | US | disclosed |
| US-12629934-B2 | Recording method and recording device | SEIKO EPSON CORPORATION (JP) | 2026-05-19 | — | — | US | disclosed |
| US-12630728-B2 | Ink set and recording method | SEIKO EPSON CORPORATION (JP) | 2026-05-19 | — | — | US | disclosed |
| US-20260125850-A1 | Pretreatment Liquid For Textile Printing And Textile Printing Method | SEIKO EPSON CORP (JP) | 2026-05-07 | — | — | US | disclosed |
| US-20260116073-A1 | Maintenance Method And Recording Apparatus | SEIKO EPSON CORP (JP) | 2026-04-30 | — | — | US | disclosed |
| US-12576663-B2 | Treatment method | SEIKO EPSON CORPORATION (JP) | 2026-03-17 | — | — | US | disclosed |
| US-12576648-B2 | Ink jet recording device | SEIKO EPSON CORPORATION (JP) | 2026-03-17 | — | — | US | disclosed |
| US-12545800-B2 | Reaction liquid for pigment printing, ink set, and recording method | SEIKO EPSON CORPORATION (JP) | 2026-02-10 | — | — | US | disclosed |
| US-20120252919-A1 | ACTIVE ENERGY RAY-CURABLE INKJET INK COMPOSITION | TOYO INK CO., LTD. (JP) | 2012-10-04 | — | — | US | disclosed |
| EP-2505624-A1 | Active energy ray-curable inkjet ink composition | Toyo Ink SC Holdings Co., Ltd. (JP) | 2012-10-03 | — | — | EP | disclosed |
| US-8137793-B2 | Ink composition and hardened material using thereof | TOYO INK MFG. CO., LTD. (JP) | 2012-03-20 | — | — | US | disclosed |
| CN-102311678-A | The active energy ray-curable ink-jet ink compsn | TOYO INK SC HOLDINGS CO LTD | 2012-01-11 | — | — | CN | disclosed |
| US-20120003435-A1 | ACTIVE ENERGY RAY CURABLE INKJET INK COMPOSITION | TOYO INK CO., LTD. (JP) | 2012-01-05 | — | — | US | disclosed |
| EP-2402405-A1 | Active energy ray curable inkjet ink composition | Toyo Ink SC Holdings Co., Ltd. (JP) | 2012-01-04 | — | — | EP | disclosed |
| US-20100317775-A1 | NONAQUEOUS INKJET INK AND INK SET | TOYO INK MFG. CO., LTD. (JP) | 2010-12-16 | — | — | US | disclosed |
| US-20100233448-A1 | INK COMPOSITION AND HARDENED MATERIAL USING THEREOF | TOYO INK MFG. CO., LTD. (JP) | 2010-09-16 | — | — | US | disclosed |
| EP-2228416-A1 | Ink composition and hardened material using thereof | Toyo Ink Mfg. Co. Ltd. (JP) | 2010-09-15 | — | — | EP | disclosed |
| EP-2083054-A1 | NONAQUEOUS INKJET INK AND INK SET | Toyo Ink Mfg. Co. Ltd. (JP) | 2009-07-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260125850-A1 | Pretreatment Liquid For Textile Printing And Textile Printing Method | ADH1A, RARA, RBP4 | ESR1 964/4885FFAR3 1610/4885HDAC3 3735/4885 |
| US-12576663-B2 | Treatment method | EPCAM, FLNA, TAS2R8 | ESR1 393/4885FFAR3 2196/4885HDAC3 4685/4885 |
| US-12637578-B2 | Ink jet ink composition and recording method | TYR, RB1, WNT1 | ESR1 1459/4885FFAR3 3850/4885HDAC3 4381/4885 |
| US-12630973-B2 | Recording method | DOT1L, EMD, EZH2 | ESR1 1996/4885FFAR3 4216/4885HDAC3 1627/4885 |
| US-12576648-B2 | Ink jet recording device | L1CAM, PRDM9, KCNJ2 | ESR1 3079/4885FFAR3 4288/4885HDAC3 2944/4885 |
| US-20260116073-A1 | Maintenance Method And Recording Apparatus | WFS1, HCN2, SMN1; SMN2 | ESR1 2609/4885FFAR3 4447/4885HDAC3 3279/4885 |
| US-12629934-B2 | Recording method and recording device | HCN2, MC1R, TYR | ESR1 4802/4885FFAR3 3593/4885HDAC3 4083/4885 |
| US-12545800-B2 | Reaction liquid for pigment printing, ink set, and recording method | PARN, PARG, TYR | ESR1 4093/4885FFAR3 4317/4885HDAC3 3124/4885 |
| US-12630728-B2 | Ink set and recording method | DOT1L, SET, ALKBH3 | ESR1 2945/4885FFAR3 4053/4885HDAC3 1161/4885 |
| US-12637804-B2 | Ink jet recording method | IK, PRPH, SLC6A19 | ESR1 4057/4885FFAR3 3092/4885HDAC3 3114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.