Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL26966251 | 0.96 | — | — | |
| SCHEMBL9257533 | 0.78 | — | — | |
| SCHEMBL1397121 | 0.78 | — | — | |
| SCHEMBL15780500 | 0.77 | — | — | |
| SCHEMBL5973062 | 0.77 | POLB (0.33) | — | |
| SCHEMBL7973620 | 0.77 | — | — | |
| SCHEMBL13072517 | 0.72 | — | — | |
| SCHEMBL9253272 | 0.72 | PPM1B (0.34) | — | |
| SCHEMBL420577 | 0.68 | ALDH1A1 (0.40) | — | |
| SCHEMBL10620023 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5660937-A | CURABLE HEAT SENSITIVE MIXTURE COATINGS COMPRISING ONE OR TWO UNSATURATE ESTER COMPOUNDS WITH ETHER OR THIOETHER GROUP, THERMAL LATENT ACID CATALYST; STORAGE STABILITY, ACID RESISTANCE, WEATHERPROOFING; CLEAR COATINGS, OVERCOATINGS | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1997-08-26 | — | — | US | claimed |
| US-20180057632-A1 | CONDUCTIVE COMPOSITION FOR FORMING SOLAR CELL COLLECTOR ELECTRODE, SOLAR CELL, AND SOLAR CELL MODULE | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2018-03-01 | — | — | US | disclosed |
| US-9072205-B1 | Surface mounting method utilizing active resin composition | SAN-EI KAGAKU CO., LTD. (JP) | 2015-06-30 | — | — | US | disclosed |
| US-20150158103-A1 | SURFACE MOUNTING METHOD UTILIZING ACTIVE RESIN COMPOSITION | SAN-EI KAGAKU CO., LTD. (JP) | 2015-06-11 | — | — | US | disclosed |
| US-8921359-B2 | Inhibitors of beta-secretase | VITAE PHARMACEUTICALS, INC. (US) | 2014-12-30 | — | — | US | disclosed |
| EP-2324032-B1 | INHIBITORS OF BETA-SECRETASE | VITAE PHARMACEUTICALS INC (US) | 2014-10-01 | — | — | EP | disclosed |
| US-20130317014-A1 | INHIBITORS OF BETA-SECRETASE | VITAE PHARMACEUTICALS, INC. | 2013-11-28 | — | — | US | disclosed |
| US-8450308-B2 | Inhibitors of beta-secretase | VITAE PHARMACEUTICALS, INC. (US) | 2013-05-28 | — | — | US | disclosed |
| US-20120168219-A1 | ACTIVE RESIN COMPOSITION, SURFACE MOUNTING METHOD AND PRINTED WIRING BOARD | SAN-EI KAGAKU CO., LTD (JP) | 2012-07-05 | — | — | US | disclosed |
| US-20110218192-A1 | Inhibitors Of Beta-Secretase | VITAE PHARMACEUTICALS, INC. (US) | 2011-09-08 | — | — | US | disclosed |
| EP-0451738-A2 | Thermosetting compositions, thermal latent carboxyl compounds and methods of preparation thereof | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1991-10-16 | — | — | EP | disclosed |
| US-4914206-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| EP-0142969-B1 | MILBEMYCIN 5-CARBONATE DERIVATIVES, THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | SANKYO COMPANY LIMITED (JP) | 1989-05-31 | — | — | EP | disclosed |
| US-4760054-A | administering parasiticides, insecticides to the animal | SANKYO COMPANY LIMITED (JP) | 1988-07-26 | — | — | US | disclosed |
| EP-0226896-A2 | Lankacidin derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1987-07-01 | — | — | EP | disclosed |
| US-4677190-A | Synthesis and ring-opening polymerization of bicyclic lactones containing a tetrahydropyran ring | UNIVERSITY PATENTS, INC. (US) | 1987-06-30 | — | — | US | disclosed |
| EP-0210065-A1 | 6-Alkylidene penems | BEECHAM GROUP PLC (GB) | 1987-01-28 | — | — | EP | disclosed |
| EP-0142969-A1 | Milbemycin 5-carbonate derivatives, their preparation and compositions containing them | SANKYO COMPANY LIMITED (JP) | 1985-05-29 | — | — | EP | disclosed |
| US-4112097-A | QUINAZOLINES | ABBOTT LABORATORIES (US) | 1978-09-05 | — | — | US | disclosed |
| US-4026894-A | 2(4(TETRAHYDRO-2-FUROYL)-PIPERAZINO)-4-AMINO-6,7-DIMETHOXYQUINAZOLINE OR 2-(4(TETRAHYDROPYRAN-2-CARBONYL)-PIPERAZINYL)-4-AMINO-6,7 -DIMETHOXYQUINAZOLINE | ABBOTT LABORATORIES (US) | 1977-05-31 | — | — | US | disclosed |