SCHEMBL1821982

SCHEMBL1821982

Cc1cccc2oc(S)nc12

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ELANE P08246 4/20 0.41
FBP1 P09467 1/20 0.39
F2RL3 Q96RI0 4/20 0.38
AGPAT2 O15120 1/20 0.36
P2RY6 Q15077 1/20 0.36
CEPT1 Q9Y6K0 1/20 0.35
ALDH1A1 P00352 1/20 0.35
KDM4E B2RXH2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29878469 0.84 NPC1 (0.42) ELANEALDH1A1KDM4E
SCHEMBL19895802 0.79 PSMD14 (0.42)
SCHEMBL5537231 0.79 ELANE (0.61) ELANEFBP1F2RL3AGPAT2ALDH1A1
Ammonia Solution, Strong SCHEMBL28600968 0.78 ELANE (0.59) ELANEFBP1F2RL3AGPAT2ALDH1A1
SCHEMBL5537227 0.76 ELANE (0.41) ELANEFBP1F2RL3AGPAT2P2RY6
SCHEMBL288843 0.76 ALDH1A1 (0.43) ELANEFBP1F2RL3AGPAT2P2RY6
SCHEMBL1821481 0.76 FBP1 (0.45) ELANEFBP1F2RL3AGPAT2P2RY6
SCHEMBL9390262 0.76 ELANE (0.39) ELANEF2RL3ALDH1A1KDM4E
SCHEMBL5485869 0.76 PSMB8 (0.35) ALDH1A1KDM4E
SCHEMBL9147142 0.76 KDM4E (0.35) ELANEKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025071094-A1 USES OF MERCAPTO FUNCTIONAL COMPOUND HAVING TYROSINASE INHIBITORY ACTIVITY 부산대학교 산학협력단 2025-04-03 WO claimed
WO-2025071094-A1 USES OF MERCAPTO FUNCTIONAL COMPOUND HAVING TYROSINASE INHIBITORY ACTIVITY 부산대학교 산학협력단 2025-04-03 WO disclosed
CN-115124485-B Sulfoxide-containing benzoxazole derivative, and preparation method and application thereof 中国医学科学院药物研究所 2023-12-15 CN disclosed
US-20230312878-A1 RUBBER COMPOSITION AND CROSSLINKED RUBBER MOLDED PRODUCT SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2023-10-05 US disclosed
US-20230312878-A1 RUBBER COMPOSITION AND CROSSLINKED RUBBER MOLDED PRODUCT SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2023-10-05 US disclosed
CN-115124485-A Benzoxazole derivatives containing sulfoxide as well as preparation method and application thereof 中国医学科学院药物研究所 2022-09-30 CN disclosed
CN-106574125-B Color material dispersion liquid, colored resin composition for color filter, and display device DNP精细化工股份有限公司 2019-05-17 CN disclosed
CN-106574999-B Colored resin composition for color filter, and display device DNP精细化工股份有限公司 2019-03-22 CN disclosed
CN-106574999-A Colored resin composition for color filter, and display device DNP精细化工股份有限公司 2017-04-19 CN disclosed
CN-106574125-A Color material dispersion liquid, colored resin composition for color filter, and display device DNP精细化工股份有限公司 2017-04-19 CN disclosed
US-20080132490-A1 Substituted diazepan orexin receptor antagonists MERCK SHARP & DOHME LLC 2008-06-05 US disclosed
US-20080132490-A1 Substituted diazepan orexin receptor antagonists MERCK SHARP & DOHME LLC 2008-06-05 US disclosed
US-7220740-B2 1,4-diazabicyclo[3.2.2]nonabenzoxazole, -benzothiazole and benzimidazole derivatives, preparation and therapeutic use thereof SANOFI-AVENTIS (FR) 2007-05-22 US disclosed
EP-1289988-B1 1,4-DIAZABICYCLO 3.2.2]NONABENZOXAZOLE, -BENZOTHIAZOLE AND BENZIMIDAZOLE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF SANOFI SYNTHELABO (FR) 2004-05-19 EP disclosed
US-20030153574-A1 1,4-diazabicyclo[3.2.2]nonabenzoxazole, -benzothiazole and benzimidazole derivatives, preparation and therapeutic use thereof SANOFI (FR) 2003-08-14 US disclosed
EP-1289988-A1 1,4-DIAZABICYCLO 3.2.2]NONABENZOXAZOLE, -BENZOTHIAZOLE AND BENZIMIDAZOLE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF SANOFI-SYNTHELABO (FR) 2003-03-12 EP disclosed
WO-2001092261-A1 1,4-DIAZABICYCLO[3.2.2]NONABENZOXAZOLE, -BENZOTHIAZOLE AND BENZIMIDAZOLE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF SANOFI-SYNTHELABO (FR) 2001-12-06 WO disclosed
WO-1994006782-A1 BENZOXAZOLE AND BEZOTHIAZOLE DERIVATIVES ZENECA LIMITED (GB) 1994-03-31 WO disclosed
US-4740596-A Process for preparation of 4-sulfonylthio azetidinone derivatives OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1988-04-26 US disclosed
US-4713452-A Process for preparation of azetidinone derivatives OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1987-12-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080132490-A1 Substituted diazepan orexin receptor antagonists HCRTR2, HCRTR1, CRHR1 ELANE 2925/4885FBP1 1378/4885F2RL3 721/4885
US-20030153574-A1 1,4-diazabicyclo[3.2.2]nonabenzoxazole, -benzothiazole and benzimidazole derivatives, preparation and therapeutic use thereof IL4I1, MT-CO1, CBR1 ELANE 2863/4885FBP1 1398/4885F2RL3 3465/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.