SCHEMBL18249581

SCHEMBL18249581

C[C@H](Nc1ccccc1)C(=O)OCc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.55
MAPT P10636 1/20 0.55
HPGD P15428 1/20 0.55
HSD17B10 Q99714 1/20 0.55
MAPK1 P28482 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
SLC6A2 P23975 1/20 0.47
SLC6A3 Q01959 1/20 0.47
KMT2A Q03164 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
ATM Q13315 2/20 0.47
RAB9A P51151 2/20 0.47
MGLL Q99685 1/20 0.47
CTSB P07858 1/20 0.46
NPC1 O15118 1/20 0.45
POLB P06746 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27311346 1.00 ALDH1A1 (0.55) ALDH1A1MAPTHPGDHSD17B10MAPK1
Hydrochloric Acid SCHEMBL17824412 0.98 ALDH1A1 (0.54) ALDH1A1MAPTHPGDHSD17B10MAPK1
Trifluoroacetic Acid SCHEMBL28276760 0.91 MAPT (0.49) ALDH1A1MAPTHPGDHSD17B10KMT2A
Hydrochloric Acid SCHEMBL6738405 0.90 ALDH1A1 (0.50) ALDH1A1MAPTHPGDHSD17B10MGLL
SCHEMBL25046474 0.88 ALDH1A1 (0.49) ALDH1A1MAPTHPGDHSD17B10KMT2A
SCHEMBL22692566 0.84 ALDH1A1 (0.58) ALDH1A1MAPTHPGDHSD17B10MAPK1
SCHEMBL4415396 0.83 OPRK1 (0.51) ALDH1A1MAPTHPGDHSD17B10MAPK1
SCHEMBL4415399 0.83 OPRK1 (0.51) ALDH1A1MAPTHPGDHSD17B10MAPK1
SCHEMBL8031605 0.83 ELANE (0.53) ALDH1A1MAPTHSD17B10MAPK1KMT2A
SCHEMBL655368 0.83 ELANE (0.53) ALDH1A1MAPTHSD17B10MAPK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250213645-A1 PHARMACEUTICAL COMPOSITION FOR MODULATING IMMUNE RESPONSE L-Base Co., Ltd. (KR) 2025-07-03 US disclosed
EP-3994122-B1 N-FORMYLHYDROXYLAMINES AS NEPRILYSIN (NEP) INHIBITORS, IN PARTICULAR AS MIXED INHIBITORS OF AMINOPEPTIDASE N (APN) AND NEPRILYSIN (NEP) KOS THERAPEUTICS INC (US) 2024-09-04 EP disclosed
US-20240207355-A1 PHARMACEUTICAL COMPOSITION FOR ENHANCING ANTICANCER EFFECT OF ANTICANCER DRUG L-Base Co., Ltd. (KR) 2024-06-27 US disclosed
EP-4062974-B1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER L BASE CO LTD (KR) 2024-05-08 EP disclosed
EP-4335452-A1 PHARMACEUTICAL COMPOSITION FOR ENHANCING ANTICANCER EFFECT OF ANTICANCER DRUG L-Base Co., Ltd. (KR) 2024-03-13 EP disclosed
CN-117083074-A Pharmaceutical composition for enhancing anticancer effect of anticancer drug L 基础有限公司 2023-11-17 CN disclosed
US-20230159587-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER L-Base Co., Ltd. (KR) 2023-05-25 US disclosed
WO-2023043261-A1 PHARMACEUTICAL COMPOSITION FOR ENHANCING ANTICANCER EFFECT OF ANTICANCER DRUG 주식회사 엘베이스 2023-03-23 WO disclosed
WO-2023043269-A1 PHARMACEUTICAL COMPOSITION FOR MODULATING IMMUNE RESPONSE 주식회사 엘베이스 2023-03-23 WO disclosed
WO-2023043271-A1 METHOD FOR CHARACTERIZING RESPONDER TO CAGE INHIBITOR FOR CANCER THERAPY 주식회사 엘베이스 2023-03-23 WO disclosed
EP-3342599-B1 HEAT-SENSITIVE RECORDING MATERIAL SANKO CO LTD (JP) 2021-06-16 EP disclosed
US-10800809-B2 Processes for the preparation of carfilzomib or pharmaceutically acceptable salts thereof LAURUS LABS LIMITED (IN) 2020-10-13 US disclosed
US-20190284231-A1 PROCESSES FOR THE PREPARATION OF CARFILZOMIB OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF LAURUS LABS LIMITED (IN) 2019-09-19 US disclosed
US-10364269-B2 Processes for the preparation of carfilzomib or pharmaceutically acceptable salts thereof LAURUS LABS LIMITED (IN) 2019-07-30 US disclosed
US-20190085026-A1 AN IMPROVED PROCESSES FOR THE PREPARATION OF CARFILZOMIB OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF Laurus Labs Ltd. (IN) 2019-03-21 US disclosed
US-10086634-B2 Heat-sensitive recording material SANKO CO., LTD. (JP) 2018-10-02 US disclosed
US-20180194151-A1 HEAT-SENSITIVE RECORDING MATERIAL SANKO CO., LTD. (JP) 2018-07-12 US disclosed
EP-3342599-A1 HEAT-SENSITIVE RECORDING MATERIAL Sanko Co., Ltd. (JP) 2018-07-04 EP disclosed
EP-3297678-A1 AN IMPROVED PROCESSES FOR THE PREPARATION OF CARFILZOMIB OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF Laurus Labs Private Limited (IN) 2018-03-28 EP disclosed
WO-2016185450-A1 AN IMPROVED PROCESSES FOR THE PREPARATION OF CARFILZOMIB OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF LAURUS LABS PRIVATE LIMITED (IN) 2016-11-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180194151-A1 HEAT-SENSITIVE RECORDING MATERIAL ASIC1, SCN1A, NPR1 ALDH1A1 1820/4885MAPT 4261/4885HPGD 2285/4885
US-20230159587-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER VIP, QPCT, TPT1 ALDH1A1 4754/4885MAPT 633/4885HPGD 1710/4885
US-20190085026-A1 AN IMPROVED PROCESSES FOR THE PREPARATION OF CARFILZOMIB OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF PRCP, SF3B5, GBA1 ALDH1A1 3950/4885MAPT 2129/4885HPGD 4740/4885
US-10364269-B2 Processes for the preparation of carfilzomib or pharmaceutically acceptable salts thereof SF3B5, PRCP, GBA1 ALDH1A1 3880/4885MAPT 1281/4885HPGD 4735/4885
US-20250213645-A1 PHARMACEUTICAL COMPOSITION FOR MODULATING IMMUNE RESPONSE ATG7, CCL11, ATG13 ALDH1A1 4701/4885MAPT 415/4885HPGD 2155/4885
US-10086634-B2 Heat-sensitive recording material ASIC1, SCN1A, NPR1 ALDH1A1 1666/4885MAPT 3657/4885HPGD 2311/4885
US-10800809-B2 Processes for the preparation of carfilzomib or pharmaceutically acceptable salts thereof SF3B5, PRCP, GBA1 ALDH1A1 3880/4885MAPT 1281/4885HPGD 4735/4885
US-20240207355-A1 PHARMACEUTICAL COMPOSITION FOR ENHANCING ANTICANCER EFFECT OF ANTICANCER DRUG ALPG, SLC11A2, SGTA ALDH1A1 4761/4885MAPT 1532/4885HPGD 3278/4885
US-20190284231-A1 PROCESSES FOR THE PREPARATION OF CARFILZOMIB OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF SF3B5, PRCP, GBA1 ALDH1A1 3880/4885MAPT 1281/4885HPGD 4735/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.