Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31309821 | 1.00 | FAAH (0.49) | FAAHPARP1HDAC8HDAC6ACHE | |
| SCHEMBL20006580 | 0.83 | TAAR1 (0.43) | FAAHPARP1HDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL14108353 | 0.76 | KMO (0.50) | HDAC8MEN1KMT2ATDP1GRM5 | |
| SCHEMBL1411277 | 0.76 | PARP1 (0.54) | FAAHPARP1HDAC8HDAC6ACHE | |
| SCHEMBL9528530 | 0.76 | PARP1 (0.54) | FAAHPARP1HDAC8HDAC6ACHE | |
| SCHEMBL12127801 | 0.75 | HDAC8 (0.50) | PARP1HDAC8HDAC6ACHESMN1; SMN2 | |
| SCHEMBL775679 | 0.75 | PARP1 (0.59) | PARP1HDAC8HDAC6SMN1; SMN2NPC1 | |
| SCHEMBL2320794 | 0.75 | ALDH1A1 (0.47) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL8116161 | 0.75 | CES2 (0.56) | PARP1HDAC8HDAC6SMN1; SMN2NPC1 | |
| SCHEMBL2163770 | 0.74 | PARP1 (0.57) | FAAHPARP1HDAC8HDAC6ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9962469-B2 | Adhesion-preventing preparation comprising composition comprising polycationic triblock copolymer and polyanionic polymer | UNIVERSITY OF TSUKUBA (JP) | 2018-05-08 | — | — | US | disclosed |
| US-9962469-B2 | Adhesion-preventing preparation comprising composition comprising polycationic triblock copolymer and polyanionic polymer | UNIVERSITY OF TSUKUBA (JP) | 2018-05-08 | — | — | US | disclosed |
| US-20180085395-A1 | POLYION COMPLEX OF POLY(L-ARGININE) SEGMENT-CONTAINING BLOCK COPOLYMER AND POLYANIONIC POLYMER | General Incorporated Association Tsukuba Global Innovation Promotion Agency (JP) | 2018-03-29 | — | — | US | disclosed |
| US-20160346438-A1 | ADHESION-PREVENTING PREPARATION COMPRISING COMPOSITION COMPRISING POLYCATIONIC TRIBLOCK COPOLYMER AND POLYANIONIC POLYMER | UNIVERSITY OF TSUKUBA (JP) | 2016-12-01 | — | — | US | disclosed |
| US-20160346438-A1 | ADHESION-PREVENTING PREPARATION COMPRISING COMPOSITION COMPRISING POLYCATIONIC TRIBLOCK COPOLYMER AND POLYANIONIC POLYMER | UNIVERSITY OF TSUKUBA (JP) | 2016-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160346438-A1 | ADHESION-PREVENTING PREPARATION COMPRISING COMPOSITION COMPRISING POLYCATIONIC TRIBLOCK COPOLYMER AND POLYANIONIC POLYMER | EPCAM, VCAM1, ICAM1 | FAAH 2974/4885PARP1 195/4885HDAC8 2117/4885 |
| US-20180085395-A1 | POLYION COMPLEX OF POLY(L-ARGININE) SEGMENT-CONTAINING BLOCK COPOLYMER AND POLYANIONIC POLYMER | ARG1, NOS2, ARG2 | FAAH 4614/4885PARP1 114/4885HDAC8 3332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.