Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.32 |
| ▸ | HNF4A | P41235 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SOD1 | P00441 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18290354 | 0.84 | SOD1 (0.41) | MAPTSOD1 | |
| SCHEMBL18290203 | 0.78 | CACNA1G (0.32) | — | |
| SCHEMBL18290216 | 0.65 | HNF4A (0.32) | RXRAHNF4A | |
| SCHEMBL17403057 | 0.64 | CACNA1G (0.44) | MAPTSOD1ACHE | |
| SCHEMBL18290213 | 0.62 | SOD1 (0.41) | MAPTSOD1 | |
| SCHEMBL19915505 | 0.57 | SLC10A2 (0.34) | ALDH1A1MAPT | |
| Salvinolone SCHEMBL29931087 | 0.55 | FDPS (0.45) | KDM4EALDH1A1MAPT | |
| SCHEMBL26030950 | 0.54 | TSHR (0.53) | RXRAALDH1A1MAPT | |
| SCHEMBL2625747 | 0.54 | LMNA (0.47) | ALDH1A1MAPTHTT | |
| SCHEMBL16499589 | 0.54 | SOD1 (0.43) | ALDH1A1MAPTSOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016192631-A1 | ABIETANE-TYPE DITERPENE COMPOUND HAVING LIPID-LOWERING ACTIVITY, METHOD FOR PREPARING SAME, AND USE OF SAME | 中国科学院上海药物研究所 | 2016-12-08 | — | — | WO | disclosed |