SCHEMBL184258

SCHEMBL184258

O=Cc1ccccc1-c1ccccc1-c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.52
KMT2A Q03164 2/20 0.52
MEN1 O00255 1/20 0.52
THRB P10828 1/20 0.52
BLM P54132 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
XDH P47989 1/20 0.46
ALDH1A1 P00352 5/20 0.43
KCNN4 O15554 1/20 0.43
TSHR P16473 1/20 0.43
TRIM24 O15164 1/20 0.43
TRIM33 Q9UPN9 1/20 0.43
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
PTGS2 P35354 1/20 0.41
GAA P10253 1/20 0.41
HSD17B10 Q99714 2/20 0.39
HPGD P15428 2/20 0.39
BCL2L1 Q07817 1/20 0.39
CYP2A6 P11509 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28725386 1.00 LMNA (0.52) LMNAKMT2AMEN1THRBBLM
SCHEMBL29506697 1.00 LMNA (0.52) LMNAKMT2AMEN1THRBBLM
SCHEMBL6217997 0.96 LMNA (0.48) LMNAKMT2AMEN1THRBBLM
SCHEMBL96494 0.91 LMNA (0.57) LMNAKMT2AMEN1THRBBLM
Benzene SCHEMBL27923728 0.91 LMNA (0.57) LMNAKMT2AMEN1THRBBLM
SCHEMBL28725395 0.89 XDH (0.43) LMNAKMT2AMEN1THRBBLM
Water SCHEMBL28190393 0.88 LMNA (0.55) LMNAKMT2AMEN1THRBBLM
SCHEMBL30721661 0.88 LMNA (0.55) LMNAKMT2AMEN1THRBBLM
SCHEMBL31588841 0.88 KMT2A (0.67) LMNAKMT2AMEN1THRBBLM
SCHEMBL27511393 0.88 KMT2A (0.67) LMNAKMT2AMEN1THRBBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1990542-A Halogen-free phosphide-free flame-retardant thermosetting polymer material composition IND TECH RES INST (CN) 2007-07-04 CN claimed
US-20240366629-A1 Porphyrin Complexes as Antidotes for Carbon Monoxide Exposure and Methods of Use for Same UNIV CALIFORNIA (US) 2024-11-07 US disclosed
EP-4395773-A1 PORPHYRIN COMPLEXES AS ANTIDOTES FOR CARBON MONOXIDE EXPOSURE AND METHODS OF USE FOR SAME The Regents of the University of California (US) 2024-07-10 EP disclosed
WO-2023034447-A9 PORPHYRIN COMPLEXES AS ANTIDOTES FOR CARBON MONOXIDE EXPOSURE AND METHODS OF USE FOR SAME THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-04-20 WO disclosed
WO-2023034447-A1 PORPHYRIN COMPLEXES AS ANTIDOTES FOR CARBON MONOXIDE EXPOSURE AND METHODS OF USE FOR SAME THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-03-09 WO disclosed
CN-114230448-A Aromatic aldehyde compound of covalent-organic framework material and preparation method thereof 南京艾姆材料科技有限公司 2022-03-25 CN disclosed
EP-3062151-B1 RESIST COMPOSITION, METHOD FOR FORMING RESIST PATTERN, POLYPHENOLIC COMPOUND FOR USE IN THE COMPOSITION, AND ALCOHOLIC COMPOUND THAT CAN BE DERIVED THEREFROM MITSUBISHI GAS CHEMICAL CO (JP) 2021-05-05 EP disclosed
CN-107531598-B Compositions for treating fibrosis and fibrosis-related disorders 维克图斯生物系统有限公司 2020-10-16 CN disclosed
CN-106957217-B Polyhydric phenol compound for resist composition 三菱瓦斯化学株式会社 2020-07-24 CN disclosed
US-10654878-B2 Compounds of phosphinanes and azaphosphinanes, a process for their preparation and pharmaceutical compositions containing them LES LABORATOIRES SERVIER (FR) 2020-05-19 US disclosed
CN-100513481-C Halogen-free phosphide-free flame-retardant thermosetting polymer material composition IND TECHNOLOGY RES INST TAIWAN (CN) 2009-07-15 CN disclosed
US-20080153031-A1 Resist composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2008-06-26 US disclosed
CN-1990542-A Halogen-free phosphide-free flame-retardant thermosetting polymer material composition IND TECH RES INST (CN) 2007-07-04 CN disclosed
WO-2007008963-A1 MAO-B INHIBITORS USEFUL FOR TREATING OBESITY JENRIN DISCOVERY (US) 2007-01-18 WO disclosed
US-20070015734-A1 MAO-B INHIBITORS USEFUL FOR TREATING OBESITY JENRIN DISCOVERY (US) 2007-01-18 US disclosed
EP-1739485-A1 RESIST COMPOSITION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2007-01-03 EP disclosed
EP-1296972-A1 ARYLMETHYLAMINE DERIVATIVES FOR USE AS TRYPTASE INHIBITORS Aventis Pharmaceuticals Inc. (US) 2003-04-02 EP disclosed
WO-2001090101-A1 ARYLMETHYLAMINE DERIVATIVES FOR USE AS TRYPTASE INHIBITORS AVENTIS PHARMACEUTICALS INC. (US) 2001-11-29 WO disclosed
WO-2001081373-A2 GLYCOPEPTIDE ANTIBACTERIAL COMPOUNDS AND METHODS OF USING SAME MERCK & CO., INC. (US) 2001-11-01 WO disclosed
US-3968159-A Process for preparing azomethines MONSANTO COMPANY (US) 1976-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070015734-A1 MAO-B INHIBITORS USEFUL FOR TREATING OBESITY MAOB, MAOA, GPR119 LMNA 2069/4885KMT2A 642/4885MEN1 3283/4885
US-10654878-B2 Compounds of phosphinanes and azaphosphinanes, a process for their preparation and pharmaceutical compositions containing them TK1, AK1, PHKA1 LMNA 3479/4885KMT2A 1104/4885MEN1 3652/4885
US-20240366629-A1 Porphyrin Complexes as Antidotes for Carbon Monoxide Exposure and Methods of Use for Same MB, HMBS, HMOX2 LMNA 1804/4885KMT2A 2703/4885MEN1 4417/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.