Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4694663 | 0.79 | GAA (0.39) | GPR84ALDH1A1PARP1 | |
| SCHEMBL2073636 | 0.79 | FFAR1 (0.39) | GPR84MEN1MAPTKMT2AACHE | |
| SCHEMBL2074196 | 0.79 | IMPDH2 (0.41) | MEN1MAPTKMT2AALDH1A1TSHR | |
| SCHEMBL3381547 | 0.79 | GPR84 (0.39) | GPR84KIF11MAPK1MAP2K4MAPKAPK2 | |
| SCHEMBL2072979 | 0.76 | ABCG2 (0.42) | MEN1MAPTKMT2ACA1CA2 | |
| SCHEMBL2073808 | 0.76 | GABRA1 (0.38) | GPR84MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL2070937 | 0.76 | KIF11 (0.40) | KIF11CA2ALDH1A1TSHRGABRA1 | |
| SCHEMBL2202477 | 0.75 | GPR84 (0.36) | GPR84KIF11MAPK1MAP2K4MAPKAPK2 | |
| SCHEMBL15796682 | 0.72 | GPR84 (0.34) | GPR84CYP1A2HTR2A | |
| SCHEMBL2072643 | 0.72 | TDP1 (0.44) | GPR84MAPK1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118718-A1 | Substituted Quinoxaline Derivatives | SELVITA S.A. (PL) | 2018-05-03 | — | — | US | claimed |
| EP-3294728-A1 | SUBSTITUTED QUINOXALINE DERIVATIVES | SELVITA S.A. (PL) | 2018-03-21 | — | — | EP | claimed |
| WO-2016180537-A1 | SUBSTITUTED QUINOXALINE DERIVATIVES | SELVITA S.A. (PL) | 2016-11-17 | — | — | WO | claimed |
| US-20030171422-A1 | New nitromethyl ketones, process for preparing them and compositions containing them | MERCK PATENT GMBH (DE) | 2003-09-11 | — | — | US | claimed |
| US-6559185-B2 | Nitromethyl ketone compounds having aldose reduction inhibiting properties and methods for their use | MERCK PATENT GMBH (DE) | 2003-05-06 | — | — | US | claimed |
| US-20030069312-A1 | Antidiabetic agents | LARDY CLAUDE (FR) | 2003-04-10 | — | — | US | claimed |
| EP-0983226-A1 | NEW NITROMETHYL KETONES, PROCESS FOR PREPARING THEM AND COMPOSITIONS CONTAINING THEM | MERCK PATENT GmbH (DE) | 2000-03-08 | — | — | EP | claimed |
| EP-0741145-B1 | Olefin polymerization catalyst and process for producing polyolefin using the same | SUMITOMO CHEMICAL CO (JP) | 1999-12-29 | — | — | EP | claimed |
| WO-1998052906-A1 | NEW NITROMETHYL KETONES, PROCESS FOR PREPARING THEM AND COMPOSITIONS CONTAINING THEM | MERCK PATENT GMBH (DE) | 1998-11-26 | — | — | WO | claimed |
| US-4144340-A | ADRENERGIC BLOCKING AGENTS | DEUTSCHE GOLD UND SILBER- SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1979-03-13 | — | — | US | claimed |
| US-20230047816-A1 | PFKFB3 INHIBITORS AND THEIR USES | GERO PTE. LTD. (SG) | 2023-02-16 | — | — | US | disclosed |
| CN-109548404-B | Propylene-alpha olefin copolymer and process for producing the same | 埃克森美孚化学专利公司 | 2022-02-08 | — | — | CN | disclosed |
| US-11192961-B2 | Production of heterophasic polymers in gas or slurry phase | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2021-12-07 | — | — | US | disclosed |
| EP-3885373-A1 | PRODUCTION OF HETEROPHASIC POLYMERS IN GAS OR SLURRY PHASE | ExxonMobil Chemical Patents Inc. (US) | 2021-09-29 | — | — | EP | disclosed |
| CN-107922537-B | Preparation of multiphase polymers in gas or slurry phase | 埃克森美孚化学专利公司 | 2021-07-27 | — | — | CN | disclosed |
| EP-0280951-A1 | Amino-propanol derivatives, process for their preparation and medicines containing these compounds, as well as intermediates | Roche Diagnostics GmbH (DE) | 1988-09-07 | — | — | EP | disclosed |
| EP-0200915-A1 | Aminopropanol derivatives, process for their preparation, their use and medicines containing them | Roche Diagnostics GmbH (DE) | 1986-11-12 | — | — | EP | disclosed |
| EP-0004532-B1 | 1-ARYLOXY-3-NITRATOALKYLAMINO-2-PROPANOLS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS | MERCK PATENT GmbH (DE) | 1981-10-14 | — | — | EP | disclosed |
| US-4288452-A | 1-Aryloxy-3-nitratoalkylamino-2-propanols and use as β-receptor blocker | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1981-09-08 | — | — | US | disclosed |
| EP-0004532-A1 | 1-Aryloxy-3-nitratoalkylamino-2-propanols, process for their preparation and pharmaceutical compositions | MERCK PATENT GmbH (DE) | 1979-10-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230047816-A1 | PFKFB3 INHIBITORS AND THEIR USES | PFKFB3, PFKFB4, PFKFB1 | GPR84 3793/4885KIF11 2014/4885MAPK1 1468/4885 |
| US-20030069312-A1 | Antidiabetic agents | SLC5A1, SLC5A2, GPR119 | GPR84 2070/4885KIF11 4239/4885MAPK1 1514/4885 |
| US-20180118718-A1 | Substituted Quinoxaline Derivatives | BRCA1, NQO2, NQO1 | GPR84 3748/4885KIF11 4038/4885MAPK1 906/4885 |
| US-20030171422-A1 | New nitromethyl ketones, process for preparing them and compositions containing them | AKR1B1, AKR1A1, AKR1C1 | GPR84 3505/4885KIF11 2471/4885MAPK1 1107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.