Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 10/20 | 1.00 |
| ▸ | BACE1 | P56817 | 5/20 | 1.00 |
| ▸ | MMP2 | P08253 | 5/20 | 1.00 |
| ▸ | MMP7 | P09237 | 5/20 | 1.00 |
| ▸ | MMP14 | P50281 | 5/20 | 1.00 |
| ▸ | BCL2 | P10415 | 4/20 | 1.00 |
| ▸ | PSMB5 | P28074 | 4/20 | 1.00 |
| ▸ | SNCA | P37840 | 4/20 | 1.00 |
| ▸ | PGD | P52209 | 4/20 | 1.00 |
| ▸ | MET | P08581 | 3/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | MAPT | P10636 | 3/20 | 1.00 |
| ▸ | RECQL | P46063 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 1.00 |
| ▸ | PKM | P14618 | 3/20 | 1.00 |
| ▸ | PKMYT1 | Q99640 | 2/20 | 1.00 |
| ▸ | PGAM1 | P18669 | 2/20 | 1.00 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Epigalocatechin Gallate SCHEMBL29389587 | 1.00 | DYRK1A (1.00) | DYRK1ABACE1MMP2MMP7MMP14 | |
| Epigalocatechin Gallate SCHEMBL10198783 | 1.00 | DYRK1A (1.00) | DYRK1ABACE1MMP2MMP7MMP14 | |
| Epigalocatechin Gallate SCHEMBL30014282 | 1.00 | DYRK1A (1.00) | DYRK1ABACE1MMP2MMP7MMP14 | |
| Gallocatechin Gallate SCHEMBL30977114 | 1.00 | DYRK1A (1.00) | DYRK1ABACE1MMP2MMP7MMP14 | |
| Epigalocatechin Gallate SCHEMBL13624466 | 1.00 | DYRK1A (1.00) | DYRK1ABACE1MMP2MMP7MMP14 | |
| Epigalocatechin Gallate SCHEMBL14423426 | 1.00 | DYRK1A (1.00) | DYRK1ABACE1MMP2MMP7MMP14 | |
| Epigalocatechin Gallate SCHEMBL30909383 | 1.00 | DYRK1A (1.00) | DYRK1ABACE1MMP2MMP7MMP14 | |
| Epigalocatechin Gallate SCHEMBL8426376 | 1.00 | DYRK1A (1.00) | DYRK1ABACE1MMP2MMP7MMP14 | |
| Epigalocatechin Gallate SCHEMBL35258 | 1.00 | DYRK1A (1.00) | DYRK1ABACE1MMP2MMP7MMP14 | |
| Gallocatechin Gallate SCHEMBL49461 | 1.00 | DYRK1A (1.00) | DYRK1ABACE1MMP2MMP7MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250064996-A1 | STABILIZED COMPOSITIONS OF RADIONUCLIDES AND USES THEREOF | RAYZEBIO, INC. | 2025-02-27 | — | — | US | claimed |
| EP-4380633-A2 | STABILIZED COMPOSITIONS OF RADIONUCLIDES AND USES THEREOF | Rayzebio, Inc. (US) | 2024-06-12 | — | — | EP | claimed |
| WO-2023191839-A9 | STABILIZED COMPOSITIONS OF RADIONUCLIDES AND USES THEREOF | RAYZEBIO, INC. (US) | 2023-11-09 | — | — | WO | claimed |
| WO-2023191839-A2 | STABILIZED COMPOSITIONS OF RADIONUCLIDES AND USES THEREOF | RAYZEBIO, INC. (US) | 2023-10-05 | — | — | WO | claimed |
| EP-4380633-A2 | STABILIZED COMPOSITIONS OF RADIONUCLIDES AND USES THEREOF | Rayzebio, Inc. (US) | 2024-06-12 | — | — | EP | disclosed |
| WO-2024094597-A1 | METHOD OF PREPARATION OF AMYLOIDOGENIC PROTEIN AGGREGATES AND USES THEREOF | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2024-05-10 | — | — | WO | disclosed |
| US-20240123098-A1 | STABILIZED COMPOSITIONS OF RADIONUCLIDES AND USES THEREOF | RAYZEBIO, INC. | 2024-04-18 | — | — | US | disclosed |
| US-11872236-B2 | Pharmacological agents for treating ocular diseases | CALASIA PHARMACEUTICALS, INC. (US) | 2024-01-16 | — | — | US | disclosed |
| US-11872236-B2 | Pharmacological agents for treating ocular diseases | CALASIA PHARMACEUTICALS, INC. (US) | 2024-01-16 | — | — | US | disclosed |
| US-11819556-B2 | Stabilized compositions of radionuclides and uses thereof | RAYZEBIO, INC. (US) | 2023-11-21 | — | — | US | disclosed |
| WO-2023191839-A9 | STABILIZED COMPOSITIONS OF RADIONUCLIDES AND USES THEREOF | RAYZEBIO, INC. (US) | 2023-11-09 | — | — | WO | disclosed |
| WO-2023191839-A2 | STABILIZED COMPOSITIONS OF RADIONUCLIDES AND USES THEREOF | RAYZEBIO, INC. (US) | 2023-10-05 | — | — | WO | disclosed |
| US-20130090300-A1 | INHIBITORS OF INFLUENZA ENDONUCLEASE ACTIVITY AND TOOLS FOR THEIR DISCOVERY | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2013-04-11 | — | — | US | disclosed |
| US-20130090300-A1 | INHIBITORS OF INFLUENZA ENDONUCLEASE ACTIVITY AND TOOLS FOR THEIR DISCOVERY | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2013-04-11 | — | — | US | disclosed |
| WO-2012171114-A1 | SYNTHETIC EPIGALLOCATECHIN GALLATE (EGCG) ANALOGS | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2012-12-20 | — | — | WO | disclosed |
| US-20110152210-A1 | POLYPHENOL COMPOUNDS FOR INHIBITING PROTEASOME AND USES THEREOF | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2011-06-23 | — | — | US | disclosed |
| US-20110152210-A1 | POLYPHENOL COMPOUNDS FOR INHIBITING PROTEASOME AND USES THEREOF | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2011-06-23 | — | — | US | disclosed |
| US-20110144125-A1 | Anti-Arrhythmia Agents, Methods of Their Use, Methods of Their Identification and Kits Therefore | THE UAB RESEARCH FOUNDATION (US) | 2011-06-16 | — | — | US | disclosed |
| EP-2323648-A2 | ANTI-ARRHYTHMIA AGENTS, METHODS OF THEIR USE, METHODS FOR THEIR IDENTIFICATION, AND KITS THEREOFRE | The UAB Research Foundation (US) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010019914-A2 | ANTI-ARRHYTHMIA AGENTS, METHODS OF THEIR USE, METHODS FOR THEIR IDENTIFICATION, AND KITS THEREOFRE | THE UAB RESEARCH FOUNDATION (US) | 2010-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130090300-A1 | INHIBITORS OF INFLUENZA ENDONUCLEASE ACTIVITY AND TOOLS FOR THEIR DISCOVERY | DNASE1, ENDOD1, RNASEH1 | DYRK1A 2861/4885BACE1 277/4885MMP2 124/4885 |
| US-11819556-B2 | Stabilized compositions of radionuclides and uses thereof | TFRC, SLC39A14, EGFR | DYRK1A 1131/4885BACE1 1741/4885MMP2 3126/4885 |
| US-11872236-B2 | Pharmacological agents for treating ocular diseases | CRYAA, CRYAB, TTR | DYRK1A 4408/4885BACE1 139/4885MMP2 1302/4885 |
| US-20250064996-A1 | STABILIZED COMPOSITIONS OF RADIONUCLIDES AND USES THEREOF | TFRC, SLC39A14, EGFR | DYRK1A 1131/4885BACE1 1741/4885MMP2 3126/4885 |
| US-20110152210-A1 | POLYPHENOL COMPOUNDS FOR INHIBITING PROTEASOME AND USES THEREOF | PSMC1, PSME1, PSMB1 | DYRK1A 4651/4885BACE1 656/4885MMP2 1156/4885 |
| US-20240123098-A1 | STABILIZED COMPOSITIONS OF RADIONUCLIDES AND USES THEREOF | TFRC, SLC39A14, EGFR | DYRK1A 1131/4885BACE1 1741/4885MMP2 3126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.