Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY4 known ✓ | P51582 | 11/20 | 0.59 |
| ▸ | P2RY2 known ✓ | P41231 | 8/20 | 0.59 |
| ▸ | P2RY12 known ✓ | Q9H244 | 8/20 | 0.54 |
| ▸ | P2RY6 known ✓ | Q15077 | 2/20 | 0.53 |
| ▸ | P2RY1 known ✓ | P47900 | 2/20 | 0.53 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.49 |
| ▸ | MET | P08581 | 2/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NSD2 | O96028 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30311409 | 1.00 | P2RY4 (0.59) | P2RY4P2RY2P2RY12P2RY6P2RY1 | |
| SCHEMBL29354251 | 1.00 | P2RY4 (0.59) | P2RY4P2RY2P2RY12P2RY6P2RY1 | |
| SCHEMBL29350751 | 0.93 | P2RY4 (0.67) | P2RY4P2RY2P2RY12P2RY6P2RY1 | |
| SCHEMBL126076 | 0.93 | P2RY4 (0.67) | P2RY4P2RY2P2RY12P2RY6P2RY1 | |
| SCHEMBL2859796 | 0.91 | P2RY4 (0.47) | P2RY4P2RY2P2RY12P2RY6P2RY1 | |
| Hydrochloric Acid SCHEMBL30808003 | 0.91 | P2RY4 (0.65) | P2RY4P2RY2P2RY12P2RY6P2RY1 | |
| SCHEMBL29637834 | 0.88 | P2RY4 (0.61) | P2RY4P2RY2P2RY12P2RY6P2RY1 | |
| SCHEMBL15242090 | 0.88 | MEN1 (0.47) | P2RY4P2RY2P2RY12P2RY6P2RY1 | |
| SCHEMBL20143982 | 0.88 | P2RY2 (0.50) | P2RY4P2RY2P2RY12P2RY6P2RY1 | |
| SCHEMBL30106754 | 0.88 | P2RY4 (0.61) | P2RY4P2RY2P2RY12P2RY6P2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 206 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3727287-B1 | HAIR DYEING PROCESS COMPRISING A STEP OF DYEING WITH HENNA AND/OR INDIGO AND A TREATMENT STEP COMPRISING THE APPLICATION OF A COMPOSITION COMPRISING A BUFFER SYSTEM | OREAL (FR) | 2024-12-04 | — | — | EP | claimed |
| EP-3727287-A1 | HAIR DYEING PROCESS COMPRISING A STEP OF DYEING WITH HENNA AND/OR INDIGO AND A TREATMENT STEP COMPRISING THE APPLICATION OF A COMPOSITION COMPRISING A BUFFER SYSTEM | L'OREAL (FR) | 2020-10-28 | — | — | EP | claimed |
| EP-2930126-B1 | Fashionable aerosol dye | HENKEL AG & CO KGAA (DE) | 2019-10-09 | — | — | EP | claimed |
| WO-2018115451-A1 | COSMETIC COMPOSITION FOR DIRECT DYEING COMPRISING AN AQUEOUS PHASE AND A FATTY PHASE THAT ARE VISUALLY DISTINCT FROM EACH OTHER | L'OREAL (FR) | 2018-06-28 | — | — | WO | claimed |
| US-20100021396-A1 | TINTING MOUSSE | HENKEL AG & CO. KGAA (DE) | 2010-01-28 | — | — | US | claimed |
| EP-0525073-B1 | ANTHRAQUINONES AS INHIBITORS OF SULFIDE PRODUCTION FROM SULFATE-REDUCING BACTERIA | DU PONT (US) | 1994-05-25 | — | — | EP | claimed |
| US-12291637-B2 | Acidic bonding compositions and methods for restoring and color toning lightened hair | L'OREAL (FR) | 2025-05-06 | — | — | US | disclosed |
| US-20250108658-A1 | INKJET PRINTING PROCESSES FOR TEMPORARY TATTOOS | Prism Inks, Inc. (US) | 2025-04-03 | — | — | US | disclosed |
| EP-3727287-B1 | HAIR DYEING PROCESS COMPRISING A STEP OF DYEING WITH HENNA AND/OR INDIGO AND A TREATMENT STEP COMPRISING THE APPLICATION OF A COMPOSITION COMPRISING A BUFFER SYSTEM | OREAL (FR) | 2024-12-04 | — | — | EP | disclosed |
| CN-118621464-A | Electrostatic spinning solution, artificial hair fiber, and preparation method and application thereof | 香港理工大学 | 2024-09-10 | — | — | CN | disclosed |
| EP-4373460-A1 | NEW COSMETIC COMPOSITIONS CONTAINING ALOE VERA JUICE | Yodi SAS (FR) | 2024-05-29 | — | — | EP | disclosed |
| US-20240124708-A1 | ACIDIC BONDING COMPOSITIONS AND METHODS FOR RESTORING AND COLOR TONING LIGHTENED HAIR | L'OREAL (FR) | 2024-04-18 | — | — | US | disclosed |
| CN-117860613-A | Direct hair dyeing product containing cationic cassia seed gum and application thereof | 卡乐魔发(上海)国际贸易有限公司 | 2024-04-12 | — | — | CN | disclosed |
| US-6146429-A | DEVELOPER, COUPLER, BEESWAX AND PROTEIN HYDROLYZATES OR AMINO ACIDS | WELLA AKTIENGESELLSCHAFT (DE) | 2000-11-14 | — | — | US | disclosed |
| US-6106579-A | MIXTURE OF OXOCARBOXYLIC ACID AND REDUCING AGENT | WELLA AKTIENGESELLSCHAFT (DE) | 2000-08-22 | — | — | US | disclosed |
| WO-1995029977-A1 | COLOURLESS DETERGENT MIXTURES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1995-11-09 | — | — | WO | disclosed |
| EP-0525073-B1 | ANTHRAQUINONES AS INHIBITORS OF SULFIDE PRODUCTION FROM SULFATE-REDUCING BACTERIA | DU PONT (US) | 1994-05-25 | — | — | EP | disclosed |
| EP-0525073-A1 | ANTHRAQUINONES AS INHIBITORS OF SULFIDE PRODUCTION FROM SULFATE-REDUCING BACTERIA. | DU PONT (US) | 1993-02-03 | — | — | EP | disclosed |
| WO-1991015954-A1 | ANTHRAQUINONES AS INHIBITORS OF SULFIDE PRODUCTION FROM SULFATE-REDUCING BACTERIA | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-10-31 | — | — | WO | disclosed |
| US-5015263-A | Composition for coloring skin and method | CLAIROL INCORPORATED (US) | 1991-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12291637-B2 | Acidic bonding compositions and methods for restoring and color toning lightened hair | SHH, TIPRL, SMURF1 | P2RY4 2995/4885P2RY2 3364/4885P2RY12 4113/4885 |
| US-20100021396-A1 | TINTING MOUSSE | KRT18, MSN, MFAP1 | P2RY4 3449/4885P2RY2 3968/4885P2RY12 4175/4885 |
| US-20240124708-A1 | ACIDIC BONDING COMPOSITIONS AND METHODS FOR RESTORING AND COLOR TONING LIGHTENED HAIR | SHH, TIPRL, SMURF1 | P2RY4 2995/4885P2RY2 3364/4885P2RY12 4113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.