Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 20/20 | 0.64 |
| ▸ | CA1 | P00915 | 12/20 | 0.64 |
| ▸ | CA9 | Q16790 | 11/20 | 0.64 |
| ▸ | CA12 | O43570 | 10/20 | 0.64 |
| ▸ | CA7 | P43166 | 6/20 | 0.64 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.64 |
| ▸ | CA4 | P22748 | 5/20 | 0.64 |
| ▸ | CA6 | P23280 | 5/20 | 0.64 |
| ▸ | CA5A | P35218 | 5/20 | 0.64 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5893410 | 0.94 | CA2 (0.67) | CA2CA1CA9CA12CA7 | |
| SCHEMBL1919298 | 0.82 | CA2 (0.67) | CA2CA1CA9CA12CA7 | |
| SCHEMBL1148233 | 0.80 | HTR6 (0.47) | CA2CA1CA9CA12CA7 | |
| SCHEMBL309694 | 0.80 | CA2 (0.73) | CA2CA1CA9CA12CA7 | |
| SCHEMBL202948 | 0.79 | CA2 (0.81) | CA2CA1CA9CA12CA7 | |
| SCHEMBL8996770 | 0.78 | TSHR (0.42) | CA2CA1CA9CA12CA7 | |
| Mafenide SCHEMBL41628 | 0.78 | CA2 (1.00) | CA2CA1CA9CA12CA7 | |
| Mafenide SCHEMBL9295695 | 0.78 | CA2 (1.00) | CA2CA1CA9CA12CA7 | |
| SCHEMBL1804376 | 0.78 | CA2 (0.67) | CA2CA1CA9CA12CA7 | |
| Sulfamide SCHEMBL5585371 | 0.78 | CA2 (0.70) | CA2CA1CA9CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 372 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12351586-B2 | Thiophene[2,3-d]pyrimidine derivative DK6-1 and its preparation method and application | SHAN DONG UNIVERSITY (CN) | 2025-07-08 | — | — | US | claimed |
| CN-119252962-A | Polybenzimidazole proton exchange membrane modified by utilizing sulfonimide crosslinking agent, and preparation method and application thereof | 山东正熵能源科技有限公司 | 2025-01-03 | — | — | CN | claimed |
| CN-118978541-A | Novel BODIPY-based near-infrared ratio type fluorescent probe for targeted detection of endoplasmic reticulum hypochlorous acid and preparation method and application thereof | 南京林业大学 | 2024-11-19 | — | — | CN | claimed |
| US-20230061859-A1 | PYRIDO[2,3-D]PYRIMIDINE HIV-1 REVERSE TRANSCRIPTASE INHIBITOR WB3, PREPARATION METHOD AND APPLICATION THEREOF | SHAN DONG UNIVERSITY (CN) | 2023-03-02 | — | — | US | claimed |
| US-20230067045-A1 | THIOPHENE[2,3-D]PYRIMIDINE DERIVATIVE DK6-1 AND ITS PREPARATION METHOD AND APPLICATION | SHAN DONG UNIVERSITY (CN) | 2023-03-02 | — | — | US | claimed |
| CN-111217833-B | Thieno [2,3-d ] pyrimidine HIV-1 non-nucleoside reverse transcriptase inhibitor and preparation method and application thereof | 山东大学 | 2021-03-16 | — | — | CN | claimed |
| CN-111217833-A | Thieno [2,3-d ] pyrimidine HIV-1 non-nucleoside reverse transcriptase inhibitor and preparation method and application thereof | 山东大学 | 2020-06-02 | — | — | CN | claimed |
| CN-108218896-B | Thiazolopyrimidine HIV-1 reverse transcriptase inhibitor and preparation method and application thereof | 山东大学 | 2020-03-27 | — | — | CN | claimed |
| US-10590145-B2 | Tetrahydrothiopyranopyrimidine derivatives as anti-HIV agent | SHANDONG UNIVERSITY (CN) | 2020-03-17 | — | — | US | claimed |
| US-20200031844-A1 | Tetrahydrothiopyranopyrimidine derivatives as anti-HIV agent | SHANDONG UNIVERSITY (CN) | 2020-01-30 | — | — | US | claimed |
| EP-4034094-B1 | PHOSPHODIESTERASE INHIBITORS AND USE | ZENSHINE PHARMACEUTICALS NANJING GROUP CO LTD (CN) | 2026-04-15 | — | — | EP | disclosed |
| US-20260001886-A1 | ENPP1 INHIBITORS I | RE VENTURES I LLC (US) | 2026-01-01 | — | — | US | disclosed |
| US-12492183-B2 | Tetrahydroquinazoline derivatives as selective cytotoxic agents | MERCK SHARP & DOHME LLC (US) | 2025-12-09 | — | — | US | disclosed |
| US-20250367173-A1 | ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE-1 INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | LIGACHEM BIOSCIENCES INC (KR) | 2025-12-04 | — | — | US | disclosed |
| WO-2025233863-A1 | ENPP1 INHIBITORS | RE VENTURES I, LLC (US) | 2025-11-13 | — | — | WO | disclosed |
| EP-0129478-A2 | 2-Sulfamoylbenzo (b) thiophene derivatives, their preparation and pharmaceutical composition for the treatment of elevated intraocular pressure | MERCK & CO. INC. (US) | 1984-12-27 | — | — | EP | disclosed |
| US-4438112-A | PROSTAGLANDINS, ANTICOAGULANTS, ANTIASTHMA | GLAXO GROUP LIMITED (GB) | 1984-03-20 | — | — | US | disclosed |
| EP-0032432-A1 | Prostanoid compounds and their preparation and pharmaceutical formulations | GLAXO GROUP LIMITED (GB) | 1981-07-22 | — | — | EP | disclosed |
| US-4017631-A | MICROBIOCIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 1977-04-12 | — | — | US | disclosed |
| US-3991202-A | ANTIMICROBIALS | JANSSEN PHARMACEUTICA N.V. (BE) | 1976-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250367173-A1 | ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE-1 INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | ENPP1, ENPP3, SMPD1 | CA2 2066/4885CA1 4519/4885CA9 2672/4885 |
| US-12492183-B2 | Tetrahydroquinazoline derivatives as selective cytotoxic agents | ACIN1, CD4, NFATC1 | CA2 4765/4885CA1 4657/4885CA9 4668/4885 |
| US-20230061859-A1 | PYRIDO[2,3-D]PYRIMIDINE HIV-1 REVERSE TRANSCRIPTASE INHIBITOR WB3, PREPARATION METHOD AND APPLICATION THEREOF | TYMP, CDK3, TYMS | CA2 4867/4885CA1 4882/4885CA9 4847/4885 |
| US-10590145-B2 | Tetrahydrothiopyranopyrimidine derivatives as anti-HIV agent | TYMP, DPYD, TPMT | CA2 4084/4885CA1 4590/4885CA9 4026/4885 |
| US-12351586-B2 | Thiophene[2,3-d]pyrimidine derivative DK6-1 and its preparation method and application | CXCR6, TYMP, CDK6 | CA2 3912/4885CA1 3225/4885CA9 1520/4885 |
| US-20260001886-A1 | ENPP1 INHIBITORS I | ENPP1, ENPP2, ENPP3 | CA2 3450/4885CA1 4636/4885CA9 4472/4885 |
| US-20230067045-A1 | THIOPHENE[2,3-D]PYRIMIDINE DERIVATIVE DK6-1 AND ITS PREPARATION METHOD AND APPLICATION | CXCR6, TYMP, CDK6 | CA2 3912/4885CA1 3225/4885CA9 1520/4885 |
| US-20200031844-A1 | Tetrahydrothiopyranopyrimidine derivatives as anti-HIV agent | TYMP, DPYD, TPMT | CA2 4084/4885CA1 4590/4885CA9 4026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.