Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.33 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.32 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1356117 | 0.89 | USP2 (0.43) | USP2LMNAALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL515147 | 0.81 | USP2 (0.52) | USP2LMNAPLA2G2CHTTLPAR5 | |
| SCHEMBL186678 | 0.80 | USP2 (0.50) | USP2LMNAPLA2G2CHTTLPAR5 | |
| Sulfuric Acid SCHEMBL11758023 | 0.78 | USP2 (0.77) | USP2LMNATSHRMAPK1PLA2G2C | |
| SCHEMBL7461538 | 0.76 | USP2 (0.55) | USP2LMNAPLA2G2CHTTLPAR5 | |
| SCHEMBL11042040 | 0.76 | USP2 (0.75) | USP2LMNAALDH1A1SMN1; SMN2PLA2G2C | |
| SCHEMBL19640303 | 0.76 | TSHR (0.52) | LMNAALDH1A1TP53SMN1; SMN2GMNN | |
| SCHEMBL101143 | 0.76 | USP2 (0.68) | USP2LMNAALDH1A1SMN1; SMN2PLA2G2C | |
| SCHEMBL29257532 | 0.75 | ENPEP (0.47) | LMNAALDH1A1TP53SMN1; SMN2GMNN | |
| SCHEMBL8532301 | 0.75 | TSHR (0.43) | LMNAALDH1A1TP53SMN1; SMN2GMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210002441-A1 | RESIN PARTICLES AND METHOD FOR PRODUCING SAME | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2021-01-07 | — | — | US | disclosed |
| US-9280074-B2 | Toner binder and resin particle | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2016-03-08 | — | — | US | disclosed |
| US-20150274914-A1 | RESIN PARTICLES AND METHOD FOR PRODUCING SAME | SANYO CHEMICAL INDUSTRIES, LTD (JP) | 2015-10-01 | — | — | US | disclosed |
| US-20140272699-A1 | TONER BINDER AND RESIN PARTICLE | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2014-09-18 | — | — | US | disclosed |
| EP-2401658-B1 | MAGENTA TONER | CANON KK (JP) | 2014-09-17 | — | — | EP | disclosed |
| EP-1788049-B1 | THERMOSETTING AQUEOUS COATING COMPOSITION | KANSAI PAINT CO LTD (JP) | 2014-05-21 | — | — | EP | disclosed |
| EP-2256557-B1 | TONER | CANON KK (JP) | 2014-05-07 | — | — | EP | disclosed |
| US-20140080051-A1 | TONER AND METHOD FOR PRODUCING TONER | RICOH COMPANY, LTD. (JP) | 2014-03-20 | — | — | US | disclosed |
| US-8519027-B2 | Aqueous amino resin dispersions and thermosetting water-based paint compositions | KANSAI PAINT CO., LTD. (JP) | 2013-08-27 | — | — | US | disclosed |
| EP-1754737-B1 | POLYESTER RESIN AND THERMOSETTING AQUEOUS COATING COMPOSITION | KANSAI PAINT CO LTD (JP) | 2013-04-03 | — | — | EP | disclosed |
| US-20070237903-A1 | Thermosetting Water-Based Coating Composition and Method of Forming Coating Film | KANSAI PAINT CO., LTD (JP) | 2007-10-11 | — | — | US | disclosed |
| EP-1350823-B1 | Water based intercoat coating composition and multi-layer coating film-forming method by use of the same | KANSAI PAINT CO LTD (JP) | 2007-08-22 | — | — | EP | disclosed |
| EP-1788049-A1 | THERMOSETTING AQUEOUS COATING COMPOSITION | Kansai Paint Co., Ltd. (JP) | 2007-05-23 | — | — | EP | disclosed |
| EP-1770135-A1 | THERMOSETTING WATER-BASED COATING COMPOSITION AND METHOD OF FORMING COATING FILM | Kansai Paint Co., Ltd. (JP) | 2007-04-04 | — | — | EP | disclosed |
| EP-1754737-A1 | POLYESTER RESIN AND THERMOSETTING AQUEOUS COATING COMPOSITION | KANSAI PAINT CO., LTD. (JP) | 2007-02-21 | — | — | EP | disclosed |
| US-7163979-B2 | Water based intercoat coating composition and multi-layer coating film-forming method by use of the same | KANSAI PAINT CO. LTD. (JP) | 2007-01-16 | — | — | US | disclosed |
| US-20060135651-A1 | Thermosetting water-based paint and coating film-forming methods | KANSAI PAINT CO., LTD. (JP) | 2006-06-22 | — | — | US | disclosed |
| US-20060135678-A1 | Aqueous amino resin dispersions and thermosetting water-based paint compositions | KANSAI PAINT CO., LTD. (JP) | 2006-06-22 | — | — | US | disclosed |
| EP-1350823-A1 | Water based intercoat coating composition and multi-layer coating film-forming method by use of the same | Kansai Paint Co., Ltd (JP) | 2003-10-08 | — | — | EP | disclosed |
| US-20030187125-A1 | Water based intercoat coating composition and mulit-layer coating film-forming method by use of the same | KANSAI PAINT CO., LTD. (JP) | 2003-10-02 | — | — | US | disclosed |