Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.54 |
| ▸ | TTR | P02766 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30644968 | 1.00 | ALDH1A1 (0.62) | ALDH1A1CYP2A6SMN1; SMN2MTNR1BMTNR1A | |
| SCHEMBL8546955 | 0.91 | ALDH1A1 (0.55) | ALDH1A1CYP2A6SMN1; SMN2TTRKDM4E | |
| SCHEMBL17099392 | 0.87 | NPC1 (0.58) | ALDH1A1CYP2A6SMN1; SMN2TTRRELA | |
| SCHEMBL8548889 | 0.87 | ALDH1A1 (0.69) | ALDH1A1CYP2A6SMN1; SMN2TTRKDM4E | |
| SCHEMBL30866102 | 0.86 | NPC1 (0.65) | ALDH1A1CYP2A6SMN1; SMN2MTNR1BMTNR1A | |
| SCHEMBL273688 | 0.86 | NPC1 (0.65) | ALDH1A1CYP2A6SMN1; SMN2MTNR1BMTNR1A | |
| SCHEMBL3804053 | 0.85 | ALDH1A1 (0.58) | ALDH1A1CYP2A6SMN1; SMN2TTRKDM4E | |
| SCHEMBL527049 | 0.85 | ALDH1A1 (0.86) | ALDH1A1CYP2A6SMN1; SMN2TTRKDM4E | |
| SCHEMBL10709191 | 0.84 | SMN1; SMN2 (0.80) | ALDH1A1SMN1; SMN2MTNR1BMTNR1AKDM4E | |
| SCHEMBL6853633 | 0.83 | SRC (0.53) | ALDH1A1CYP2A6SMN1; SMN2TTRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2567964-B1 | Monomer compositions for the synthesis of RNA, methods of synthesis, and methods of deprotection | AGILENT TECHNOLOGIES INC (US) | 2015-02-11 | — | — | EP | claimed |
| EP-2567964-A2 | Monomer Compositions for the Synthesis of RNA, Methods of Synthesis, and Methods of Deprotection | Agilent Technologies, Inc. (US) | 2013-03-13 | — | — | EP | claimed |
| US-7759471-B2 | nucleotide monomer used to make protected RNA that has similar stability to the DNA molecule | AGILENT TECHNOLOGIES, INC. (US) | 2010-07-20 | — | — | US | claimed |
| EP-3615515-B1 | PROPIONIC ACID DERIVATIVES AND METHODS OF USE THEREOF | AVIARA PHARMACEUTICALS INC (US) | 2024-09-25 | — | — | EP | disclosed |
| CN-110914241-B | Propionic acid derivatives and methods of use thereof | 阿维亚拉药品有限公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-110317200-B | Pyrimidinium compounds and uses thereof | 东莞市东阳光农药研发有限公司 | 2020-09-11 | — | — | CN | disclosed |
| CN-110914241-A | Propionic acid derivatives and methods of use thereof | 阿维亚拉药品有限公司 | 2020-03-24 | — | — | CN | disclosed |
| EP-3615515-A2 | PROPIONIC ACID DERIVATIVES AND METHODS OF USE THEREOF | Aviara Pharmaceuticals, Inc. (US) | 2020-03-04 | — | — | EP | disclosed |
| CN-110317200-A | Pyrimidine compound and application thereof | 东莞东阳光科研发有限公司 | 2019-10-11 | — | — | CN | disclosed |
| US-20190225602-A1 | Propionic Acid Derivatives and Methods of Use Thereof | AVIARA PHARMACEUTICALS, INC. (US) | 2019-07-25 | — | — | US | disclosed |
| US-10246451-B2 | Propionic acid derivatives and methods of use thereof | AVIARA PHARMACEUTICALS, INC. (US) | 2019-04-02 | — | — | US | disclosed |
| US-8889883-B2 | BODIPY structure fluorescence dye for neural stem cell probe | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2014-11-18 | — | — | US | disclosed |
| US-8889883-B2 | BODIPY structure fluorescence dye for neural stem cell probe | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2014-11-18 | — | — | US | disclosed |
| WO-2014109713-A1 | FLUORESCENT CELL CYCLE PROBE HAVING M-PHASE SPECIFICITY | NATIONAL UNIVERISTY OF SINGAPORE (SG) | 2014-07-17 | — | — | WO | disclosed |
| US-20130244251-A1 | BODIPY Structure Fluorescence Dye for Neural Stem Cell Probe | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2013-09-19 | — | — | US | disclosed |
| US-20130244251-A1 | BODIPY Structure Fluorescence Dye for Neural Stem Cell Probe | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2013-09-19 | — | — | US | disclosed |
| US-20130178520-A1 | METHODS OF TREATMENT USING ARYLCYCLOPROPYLAMINE COMPOUNDS | DUKE UNIVERSITY (US) | 2013-07-11 | — | — | US | disclosed |
| US-20130178520-A1 | METHODS OF TREATMENT USING ARYLCYCLOPROPYLAMINE COMPOUNDS | DUKE UNIVERSITY (US) | 2013-07-11 | — | — | US | disclosed |
| US-20110106241-A1 | COMPOSITIONS AND METHODS FOR INHIBITING SPHINGOSINE KINASE | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2011-05-05 | — | — | US | disclosed |
| WO-2009146112-A1 | COMPOSITIONS AND METHODS FOR INHIBITING SPHINGOSINE KINASE | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2009-12-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10246451-B2 | Propionic acid derivatives and methods of use thereof | ITGA4, ITGB3, ITGB5 | ALDH1A1 232/4885CYP2A6 1051/4885SMN1; SMN2 2184/4885 |
| US-20110106241-A1 | COMPOSITIONS AND METHODS FOR INHIBITING SPHINGOSINE KINASE | SPHK2, SPHK1, S1PR2 | ALDH1A1 4650/4885CYP2A6 4821/4885SMN1; SMN2 1918/4885 |
| US-20130178520-A1 | METHODS OF TREATMENT USING ARYLCYCLOPROPYLAMINE COMPOUNDS | SNCA, PARK7, PNMT | ALDH1A1 2159/4885CYP2A6 1014/4885SMN1; SMN2 47/4885 |
| US-20190225602-A1 | Propionic Acid Derivatives and Methods of Use Thereof | ITGA4, ITGB3, ITGB4 | ALDH1A1 141/4885CYP2A6 1321/4885SMN1; SMN2 1998/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.