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SCHEMBL18765005

SCHEMBL18765005

CC(C)(C)OC(=O)NCCn1cc(C(=O)O)c(C(F)(F)F)n1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DGAT1 O75907 1/20 0.40
▸ ALDH1A1 P00352 1/20 0.38
▸ GFER P55789 1/20 0.38
▸ GAA P10253 2/20 0.37
▸ MEN1 O00255 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ DRD2 P14416 2/20 0.37
▸ ADORA3 P0DMS8 1/20 0.37
▸ ADORA2A P29274 1/20 0.37
▸ RORC P51449 1/20 0.37
▸ TDP1 Q9NUW8 1/20 0.36
▸ P2RY14 Q15391 1/20 0.36
▸ CCNC P24863 1/20 0.36
▸ CDK8 P49336 1/20 0.36
▸ KLKB1 P03952 1/20 0.36
▸ LMNA P02545 1/20 0.36
▸ POLB P06746 1/20 0.36
▸ MALT1 Q9UDY8 1/20 0.35
▸ IDO1 P14902 1/20 0.35
▸ SIGMAR1 Q99720 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18764872 0.86 ADORA3 (0.40) DGAT1ALDH1A1GFERGAAADORA3
SCHEMBL28231803 0.84 P2RX7 (0.40) ALDH1A1GFERGAAMEN1KMT2A
SCHEMBL21564331 0.84 ALDH1A1 (0.40) ALDH1A1GFERGAAMEN1KMT2A
SCHEMBL24931213 0.79 JAK2 (0.42) ALDH1A1GFERGAAMEN1KMT2A
SCHEMBL24930987 0.79 CKS1B (0.47) ALDH1A1KMT2ADRD2MALT1IDO1
SCHEMBL31518543 0.78 MEN1 (0.38) ALDH1A1GFERGAAMEN1KMT2A
SCHEMBL28447417 0.78 LMNA (0.50) DGAT1GAALMNAPOLB
SCHEMBL18764646 0.78 SLC40A1 (0.61) DGAT1KLKB1
SCHEMBL30239072 0.77 IDO1 (0.44) KMT2ADRD2ADORA3ADORA2AMALT1
SCHEMBL17756261 0.77 GAA (0.39) DGAT1ALDH1A1GAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3364967-B1 FERROPORTIN INHIBITORS VIFOR INT AG (CH) 2026-05-20 — — EP disclosed
EP-3365339-B1 NOVEL FERROPORTIN INHIBITORS VIFOR INT AG (CH) 2025-07-16 — — EP disclosed
US-20220363675-A1 Novel Ferroportin Inhibitors VIFOR (INTERNATIONAL) AG (CH) 2022-11-17 — — US disclosed
CN-114668761-A Novel ferroportin inhibitors 威佛（国际）股份公司 2022-06-28 — — CN disclosed
CN-108290878-B Novel ferroportin inhibitors 威佛（国际）股份公司 2022-04-26 — — CN disclosed
US-11066399-B2 Ferroportin inhibitors VIFOR (INTERNATIONAL) AG (CH) 2021-07-20 — — US disclosed
US-20210139472-A1 Novel Ferroportin Inhibitors VIFOR (INTERNATIONAL) AG (CH) 2021-05-13 — — US disclosed
US-11001579-B2 Ferroportin inhibitors VIFOR (INTERNATIONAL) AG (CH) 2021-05-11 — — US disclosed
US-10738041-B2 Ferroportin inhibitors VIFOR (INTERNATIONAL) AG (CH) 2020-08-11 — — US disclosed
US-10738041-B2 Ferroportin inhibitors VIFOR (INTERNATIONAL) AG (CH) 2020-08-11 — — US disclosed
US-10364239-B2 Ferroportin inhibitors VIFOR (INTERNATIONAL) AG (CH) 2019-07-30 — — US disclosed
US-10364239-B2 Ferroportin inhibitors VIFOR (INTERNATIONAL) AG (CH) 2019-07-30 — — US disclosed
US-20180319783-A1 Novel Ferroportin Inhibitors VIFOR (INTERNATIONAL) AG (CH) 2018-11-08 — — US disclosed
US-20180297991-A1 Novel Ferroportin Inhibitors VIFOR (INTERNATIONAL) AG (CH) 2018-10-18 — — US disclosed
EP-3365339-A1 NOVEL FERROPORTIN INHIBITORS Vifor (International) AG (CH) 2018-08-29 — — EP disclosed
EP-3364967-A2 FERROPORTIN INHIBITORS Vifor (International) AG (CH) 2018-08-29 — — EP disclosed
WO-2017068089-A2 NOVEL FERROPORTIN INHIBITORS VIFOR (INTERNATIONAL) AG (CH) 2017-04-27 — — WO disclosed
WO-2017068089-A2 NOVEL FERROPORTIN INHIBITORS VIFOR (INTERNATIONAL) AG (CH) 2017-04-27 — — WO disclosed
WO-2017068090-A1 NOVEL FERROPORTIN INHIBITORS VIFOR (INTERNATIONAL) AG (CH) 2017-04-27 — — WO disclosed
WO-2017068090-A1 NOVEL FERROPORTIN INHIBITORS VIFOR (INTERNATIONAL) AG (CH) 2017-04-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210139472-A1 Novel Ferroportin Inhibitors HAMP, SLC40A1, HMOX1 DGAT1 1612/4885ALDH1A1 2812/4885GFER 766/4885
US-10738041-B2 Ferroportin inhibitors SLC40A1, HAMP, TFRC DGAT1 2876/4885ALDH1A1 1968/4885GFER 1239/4885
US-11066399-B2 Ferroportin inhibitors HAMP, SLC40A1, FTH1 DGAT1 1618/4885ALDH1A1 2395/4885GFER 725/4885
US-20180297991-A1 Novel Ferroportin Inhibitors SLC40A1, HAMP, TFRC DGAT1 2826/4885ALDH1A1 1922/4885GFER 1483/4885
US-11001579-B2 Ferroportin inhibitors HAMP, SLC40A1, FTH1 DGAT1 1618/4885ALDH1A1 2395/4885GFER 725/4885
US-10364239-B2 Ferroportin inhibitors HAMP, SLC40A1, HMOX1 DGAT1 1803/4885ALDH1A1 1716/4885GFER 409/4885
US-20180319783-A1 Novel Ferroportin Inhibitors HAMP, SLC40A1, FTH1 DGAT1 1646/4885ALDH1A1 1983/4885GFER 578/4885
US-20220363675-A1 Novel Ferroportin Inhibitors HAMP, SLC40A1, HMOX1 DGAT1 1612/4885ALDH1A1 2812/4885GFER 766/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.