Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3601018 | 0.98 | ALDH1A1 (0.55) | ALDH1A1TDP1GAAHTTMAPK1 | |
| SCHEMBL4594016 | 0.91 | ALDH1A1 (0.47) | ALDH1A1TDP1GAAHTTMAPK1 | |
| SCHEMBL2241497 | 0.85 | ALDH1A1 (0.56) | ALDH1A1TDP1GAAHTTMAPK1 | |
| SCHEMBL3488943 | 0.81 | ALDH1A1 (0.50) | ALDH1A1GAAHTTMAPK1KMT2A | |
| SCHEMBL6117681 | 0.81 | PDK1 (0.47) | ALDH1A1TDP1GAAHTTMAPK1 | |
| SCHEMBL19172441 | 0.80 | NPC1 (0.50) | ALDH1A1GAAHTTMAPK1KMT2A | |
| Hydrochloric Acid SCHEMBL3276016 | 0.80 | ALDH1A1 (0.49) | ALDH1A1GAAHTTMAPK1KMT2A | |
| Hydrochloric Acid SCHEMBL2967978 | 0.80 | LMNA (0.49) | ALDH1A1GAAHTTMAPK1KMT2A | |
| SCHEMBL5656353 | 0.78 | MAPT (0.56) | ALDH1A1TDP1GAAHTTMAPK1 | |
| SCHEMBL16702893 | 0.77 | ALDH1A1 (0.41) | ALDH1A1GAAHTTMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 320 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240101515-A1 | SYNTHESIS OF 3-NITRO-N-(2,2,2-TRIFLUOROETHYL)-4-PYRIDINAMINE | Janssen Sciences Ireland Unlimited Company (IE) | 2024-03-28 | — | — | US | claimed |
| EP-4051663-B1 | SYNTHESIS OF 3-NITRO-N-(2,2,2-TRIFLUOROETHYL)-4-PYRIDINAMINE | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2024-02-21 | — | — | EP | claimed |
| CN-114630820-B | Synthesis of 3-nitro-N- (2, 2-trifluoroethyl) -4-pyridineamine | 杨森科学爱尔兰无限公司 | 2023-10-31 | — | — | CN | claimed |
| CN-114630820-A | Synthesis of 3-nitro-N- (2,2, 2-trifluoroethyl) -4-pyridylamine | 杨森科学爱尔兰无限公司 | 2022-06-14 | — | — | CN | claimed |
| CN-114315706-A | Synthetic method of 3, 4-diaminopyridine | 河北一品生物医药有限公司 | 2022-04-12 | — | — | CN | claimed |
| WO-2021083996-A1 | SYNTHESIS OF 3-NITRO-N-(2,2,2-TRIFLUOROETHYL)-4-PYRIDINAMINE | Janssen Sciences Ireland Unlimited Company (IE) | 2021-05-06 | — | — | WO | claimed |
| EP-3980412-B1 | 1-PYRAZOLYL, 5-, 6- DISUBSTITUTED INDAZOLE DERIVATIVES AS LRRK2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | MERCK SHARP & DOHME LLC (US) | 2025-08-13 | — | — | EP | disclosed |
| EP-3321268-B1 | BICYCLIC HETEROARYL DERIVATIVES AS MNK1 AND MNK2 MODULATORS AND USES THEREOF | AGENCY SCIENCE TECH & RES (SG) | 2025-06-04 | — | — | EP | disclosed |
| US-12319671-B2 | 1-pyrazolyl, 5-, 6-disubstituted indazole derivatives as LRRK2 inhibitors, pharmaceutical compositions, and uses thereof | MERCK SHARP & DOHME LLC (US) | 2025-06-03 | — | — | US | disclosed |
| WO-2025059074-A1 | BICYCLIC COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION | PMV PHARMACEUTICALS, INC. (US) | 2025-03-20 | — | — | WO | disclosed |
| CN-118530172-A | Pd for selectively recognizing 1, 4-benzoquinone2L4Metal organic molecular cage and preparation method thereof | 四川大学 | 2024-08-23 | — | — | CN | disclosed |
| US-20240109894-A1 | SYNTHESIS OF 3-({5-CHLORO-1-[3-(METHYLSULFONYL)PROPYL]-1H-INDOL-2-YL} METHYL)-1-(2,2,2-TRIFLUOROETHYL)-1,3-DIHYDRO-2H-IMIDAZO[4,5-C]PYRIDIN-2-ONE | JOHNSON & JOHNSON (CHINA) INVESTMENT LTD. (CN) | 2024-04-04 | — | — | US | disclosed |
| US-20240101515-A1 | SYNTHESIS OF 3-NITRO-N-(2,2,2-TRIFLUOROETHYL)-4-PYRIDINAMINE | Janssen Sciences Ireland Unlimited Company (IE) | 2024-03-28 | — | — | US | disclosed |
| US-5723468-A | COGNITION ACTIVATORS FOR MEMOY LOSS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-03-03 | — | — | US | disclosed |
| US-5698675-A | AMIDATION; ESTERIFICATION | RESEARCH CORPORATION TECH., INC. (US) | 1997-12-16 | — | — | US | disclosed |
| US-5644029-A | TRIAZOLO-PYRIDINE HETEROCYCLIC COMPOUNDS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1997-07-01 | — | — | US | disclosed |
| US-5580981-A | YELLOW INDICATORS FADING TO COLORLESS UPON COMPLETION OF THE ACYLATION STEP IN AMIDE FORMATION; REACTION ACCELERATORS; LOWERS RACEMIZATION | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1996-12-03 | — | — | US | disclosed |
| US-5571819-A | Imidazopyridines as muscarinic agents | WYETH | 1996-11-05 | — | — | US | disclosed |
| WO-1994007910-A1 | NEW REAGENTS FOR PEPTIDE COUPLINGS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1994-04-14 | — | — | WO | disclosed |
| US-5254592-A | Multiply substituted anilines, phenols and pyridines-immunomodulating agents | STERLING DRUG INC. (US) | 1993-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240109894-A1 | SYNTHESIS OF 3-({5-CHLORO-1-[3-(METHYLSULFONYL)PROPYL]-1H-INDOL-2-YL} METHYL)-1-(2,2,2-TRIFLUOROETHYL)-1,3-DIHYDRO-2H-IMIDAZO[4,5-C]PYRIDIN-2-ONE | HTR3C, MECP2, CDK2 | ALDH1A1 1540/4885TDP1 3014/4885GAA 4381/4885 |
| US-20240101515-A1 | SYNTHESIS OF 3-NITRO-N-(2,2,2-TRIFLUOROETHYL)-4-PYRIDINAMINE | NNMT, DPYD, PNMT | ALDH1A1 2394/4885TDP1 2120/4885GAA 3506/4885 |
| US-12319671-B2 | 1-pyrazolyl, 5-, 6-disubstituted indazole derivatives as LRRK2 inhibitors, pharmaceutical compositions, and uses thereof | LRRK2, PARK7, BRSK2 | ALDH1A1 2044/4885TDP1 1070/4885GAA 968/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.