Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 known ✓ | P36888 | 1/20 | 0.34 |
| ▸ | HDAC6 known ✓ | Q9UBN7 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | TERT | O14746 | 1/20 | 0.31 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2817416 | 0.98 | LMNA (0.38) | LMNATDP1TAS2R14FLT3NPSR1 | |
| Water SCHEMBL18890706 | 0.87 | NPBWR1 (0.41) | LMNATDP1ALDH1A1NPBWR1HDAC6 | |
| SCHEMBL2817421 | 0.85 | NPBWR1 (0.42) | LMNATDP1ALDH1A1NPBWR1HDAC6 | |
| Water SCHEMBL28362650 | 0.84 | HDAC6 (0.44) | TDP1TAS2R14ALDH1A1HSD17B10HDAC6 | |
| Water SCHEMBL28362573 | 0.83 | HDAC6 (0.43) | TDP1TAS2R14ALDH1A1HSD17B10HDAC6 | |
| SCHEMBL3391197 | 0.82 | MAPT (0.44) | LMNATDP1ALDH1A1HSD17B10 | |
| SCHEMBL1160168 | 0.82 | HDAC6 (0.46) | LMNATDP1TAS2R14ALDH1A1HSD17B10 | |
| SCHEMBL2817420 | 0.81 | HDAC6 (0.44) | LMNATDP1TAS2R14ALDH1A1HSD17B10 | |
| Ensulizole SCHEMBL3173641 | 0.74 | NPBWR1 (0.58) | LMNAALDH1A1MAPK1HSD17B10NPBWR1 | |
| SCHEMBL11094785 | 0.72 | ACR (0.52) | LMNANPSR1ALDH1A1MAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12269904-B2 | Sulfur-modified chloroprene rubber and method for producing same, sulfur-modified chloroprene rubber composition, vulcanizate, and molded article | DENKA COMPANY LIMITED (JP) | 2025-04-08 | — | — | US | claimed |
| CN-118854389-A | Application of copper sulfate recovered from PCB waste liquid in electrolytic preparation of copper foil, raw material composition of electrolyte, electrolyte and preparation method of electrolyte, copper foil and preparation method and application of copper foil | 江西理工大学 | 2024-10-29 | — | — | CN | claimed |
| CN-113166281-B | Sulfur-modified chloroprene rubber and method for producing same, sulfur-modified chloroprene rubber composition, vulcanizate, and molded article | 电化株式会社 | 2023-04-18 | — | — | CN | claimed |
| EP-3971218-B1 | SULFUR-MODIFIED CHLOROPRENE RUBBER AND METHOD FOR PRODUCING SAME, SULFUR-MODIFIED CHLOROPRENE RUBBER COMPOSITION, VULCANIZATE, AND MOLDED ARTICLE | DENKA COMPANY LTD (JP) | 2023-03-15 | — | — | EP | claimed |
| CN-113661181-B | Sulfur-modified chloroprene rubber and method for producing same, sulfur-modified chloroprene rubber composition, vulcanizate, and molded article | 电化株式会社 | 2023-03-14 | — | — | CN | claimed |
| EP-3889186-B1 | SULFUR-MODIFIED CHLOROPRENE RUBBER, METHOD FOR PRODUCING SAME, SULFUR-MODIFIED CHLOROPRENE RUBBER COMPOSITION, VULCANIZED PRODUCT AND MOLDED ARTICLE | DENKA COMPANY LTD (JP) | 2022-09-28 | — | — | EP | claimed |
| US-20220213235-A1 | SULFUR-MODIFIED CHLOROPRENE RUBBER AND METHOD FOR PRODUCING SAME, SULFUR-MODIFIED CHLOROPRENE RUBBER COMPOSITION, VULCANIZATE, AND MOLDED ARTICLE | DENKA COMPANY LIMITED (JP) | 2022-07-07 | — | — | US | claimed |
| CN-113113321-B | Semiconductor high-density lead frame and manufacturing process thereof | 昆山弗莱吉电子科技有限公司 | 2022-02-11 | — | — | CN | claimed |
| CN-113661181-A | Sulfur-modified chloroprene rubber and method for producing same, sulfur-modified chloroprene rubber composition, vulcanizate, and molded article | 电化株式会社 | 2021-11-16 | — | — | CN | claimed |
| EP-3889186-A1 | SULFUR-MODIFIED CHLOROPRENE RUBBER, METHOD FOR PRODUCING SAME, SULFUR-MODIFIED CHLOROPRENE RUBBER COMPOSITION, VULCANIZED PRODUCT AND MOLDED ARTICLE | Denka Company Limited (JP) | 2021-10-06 | — | — | EP | claimed |
| WO-2020230746-A1 | SULFUR-MODIFIED CHLOROPRENE RUBBER AND METHOD FOR PRODUCING SAME, SULFUR-MODIFIED CHLOROPRENE RUBBER COMPOSITION, VULCANIZATE, AND MOLDED ARTICLE | デンカ株式会社 | 2020-11-19 | — | — | WO | claimed |
| WO-2020189516-A1 | SULFUR-MODIFIED CHLOROPRENE RUBBER, METHOD FOR PRODUCING SAME, SULFUR-MODIFIED CHLOROPRENE RUBBER COMPOSITION, VULCANIZED PRODUCT AND MOLDED ARTICLE | デンカ株式会社 | 2020-09-24 | — | — | WO | claimed |
| CN-111041533-A | Electroplating solution for electroplating pure cobalt and application thereof | 苏州清飙科技有限公司 | 2020-04-21 | — | — | CN | claimed |
| CN-110819343-A | Preparation method and application of red fluorescent copper nanocluster | 山西大学 | 2020-02-21 | — | — | CN | claimed |
| US-20180112321-A1 | ACIDIC COPPER PLATING SOLUTION, ACIDIC COPPER PLATED PRODUCT, AND METHOD FOR PRODUCING SEMICONDUCTOR DEVICE | FINE FEATURE ELECTRODEPOSITION RESEARCH INSTITUTE, INC. (JP) | 2018-04-26 | — | — | US | claimed |
| CN-107699883-A | A kind of green Chrome-free antirust passivating solution and preparation method thereof | 荆门市拓达科技有限公司 | 2018-02-16 | — | — | CN | claimed |
| CN-107326349-A | High-performance multi-component alloy catalytic liquid and preparation method thereof | 荆门市拓达科技有限公司 | 2017-11-07 | — | — | CN | claimed |
| CN-104630756-A | Method for forming high-thermal-conducting hydrophilic nano ceramic film on surface of aluminum | SUZHOU ULTRAPOWER ENERGY STORAGE TECHNOLOGY CO LTD | 2015-05-20 | — | — | CN | claimed |
| CN-101824209-B | Preparation method of polyester acrylate hybrid aqueous dispersion | UNIV HUNAN | 2011-09-21 | — | — | CN | claimed |
| CN-101824209-A | Preparation method of polyester acrylate hybrid aqueous dispersion | UNIV HUNAN | 2010-09-08 | — | — | CN | claimed |