SCHEMBL18905239

SCHEMBL18905239

C=Nc1c(/C=C\C)cccc1-c1ccc(-c2nc(-c3ccc4ccccc4c3)nc(-c3ccc4ccccc4c3)n2)cc1

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TP53 P04637 1/20 0.32
CYP1A2 P05177 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 1/20 0.32
BACE1 P56817 2/20 0.32
CCNC P24863 5/20 0.31
CDK8 P49336 5/20 0.31
GSTP1 P09211 1/20 0.31
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
MET P08581 1/20 0.31
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30
SLC6A3 Q01959 1/20 0.30
ACHE P22303 1/20 0.30
HDAC4 P56524 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21132114 0.88 ESR1 (0.34) KDM4EMEN1ALDH1A1TP53CYP1A2
SCHEMBL21348369 0.88 L3MBTL1 (0.36) KDM4EMEN1ALDH1A1KMT2A
SCHEMBL22745529 0.88 L3MBTL1 (0.36) KDM4EMEN1ALDH1A1KMT2A
SCHEMBL22215535 0.82 CYP1A2 (0.36) MEN1CYP1A2KMT2AMAOAMAOB
SCHEMBL19682712 0.80 MMP9 (0.36) KDM4EMEN1ALDH1A1TP53CYP1A2
SCHEMBL19091234 0.79 ACACA (0.38) KDM4EMEN1ALDH1A1TP53CYP1A2
SCHEMBL21348641 0.78 MMP9 (0.35) KDM4EMEN1ALDH1A1TP53CYP1A2
SCHEMBL22963203 0.77 TRIM58 (0.33) MEN1ALDH1A1CYP1A2KMT2AHSD17B10
SCHEMBL21215969 0.77 ALDH1A1 (0.31) KDM4EALDH1A1SMN1; SMN2
SCHEMBL22963705 0.74 ACACA (0.32) KDM4EMEN1ALDH1A1CYP1A2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240244858-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2024-07-18 US disclosed
US-20230354632-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-02 US disclosed
US-20230189635-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2023-06-15 US disclosed
US-20220173331-A1 LIGHT-EMITTING DEVICE AND AN ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2022-06-02 US disclosed
US-11316117-B2 Organometallic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2022-04-26 US disclosed
US-20210367162-A1 HETEROCYCLIC COMPOUND AND LIGHT-EMITTING DEVICE INCLUDING SAME SAMSUNG DISPLAY CO., LTD. (KR) 2021-11-25 US disclosed
US-20210367168-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2021-11-25 US disclosed
US-11171296-B2 Organometallic compound, organic light-emitting device including the same, and organic light-emitting apparatus including the organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2021-11-09 US disclosed
US-11145823-B2 Heterocyclic compound and organic light emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2021-10-12 US disclosed
US-10988447-B2 Bipyridine derivatives and their uses for organic light emitting diodes SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-04-27 US disclosed
US-20200168798-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2020-05-28 US disclosed
US-10580999-B2 Condensed cyclic compound and an organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-03-03 US disclosed
US-20190296253-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ORGANIC LIGHT-EMITTING APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2019-09-26 US disclosed
US-20190123291-A1 LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2019-04-25 US disclosed
US-10259996-B2 Borole compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2019-04-16 US disclosed
US-20190051841-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2019-02-14 US disclosed
US-20180198074-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-07-12 US disclosed
US-20170194571-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-06 US disclosed
US-20170186979-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-29 US disclosed
US-20170155048-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (15 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11145823-B2 Heterocyclic compound and organic light emitting device including the same TRPC1, ODC1, DDT KDM4E 1975/4885MEN1 713/4885ALDH1A1 48/4885
US-20230189635-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CYP1A1, CYP1B1 KDM4E 2917/4885MEN1 618/4885ALDH1A1 11/4885
US-10988447-B2 Bipyridine derivatives and their uses for organic light emitting diodes CRY2, CRY1, CCNA1 KDM4E 4656/4885MEN1 3216/4885ALDH1A1 35/4885
US-20190051841-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME AOC2, CYP1A1, CRY1 KDM4E 4165/4885MEN1 346/4885ALDH1A1 4/4885
US-20210367168-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CYP1A1, CYP1B1 KDM4E 2917/4885MEN1 618/4885ALDH1A1 11/4885
US-20170186979-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, LEF1, CRY2 KDM4E 2595/4885MEN1 504/4885ALDH1A1 8/4885
US-20200168798-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME OCIAD1, L3MBTL1, OCIAD2 KDM4E 3548/4885MEN1 85/4885ALDH1A1 817/4885
US-11171296-B2 Organometallic compound, organic light-emitting device including the same, and organic light-emitting apparatus including the organic light-emitting device OCIAD1, ORC3, ORMDL3 KDM4E 1700/4885MEN1 357/4885ALDH1A1 24/4885
US-10259996-B2 Borole compound and organic light-emitting device including the same HBS1L, OXA1L, BOD1L1 KDM4E 3981/4885MEN1 139/4885ALDH1A1 390/4885
US-20240244858-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE CRY1, CRY2, C1S KDM4E 3690/4885MEN1 357/4885ALDH1A1 1656/4885
US-20170194571-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNA1 KDM4E 3545/4885MEN1 389/4885ALDH1A1 237/4885
US-11316117-B2 Organometallic compound and organic light-emitting device including the same OCIAD1, L3MBTL1, OCIAD2 KDM4E 3548/4885MEN1 85/4885ALDH1A1 817/4885
US-20190296253-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ORGANIC LIGHT-EMITTING APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE OCIAD1, ORC3, ORMDL3 KDM4E 1700/4885MEN1 357/4885ALDH1A1 24/4885
US-20180198074-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CYP1A1 KDM4E 3038/4885MEN1 382/4885ALDH1A1 24/4885
US-10580999-B2 Condensed cyclic compound and an organic light-emitting device including the same CRY1, CRY2, CCNA1 KDM4E 3545/4885MEN1 389/4885ALDH1A1 237/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.