Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 5/20 | 0.54 |
| ▸ | TNF | P01375 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | RPS6KA3 | P51812 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | LYN | P07948 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | MARK3 | P27448 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.43 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29157896 | 0.86 | GAA (0.48) | CYP2A6NOTUMRPS6KA3GAANPC1 | |
| Hydrochloric Acid SCHEMBL6440875 | 0.83 | CYP2A6 (0.55) | CYP2A6TNFRPS6KA3NPC1RAB9A | |
| SCHEMBL3306203 | 0.83 | CYP2A6 (0.54) | CYP2A6TNFNOTUMRPS6KA3GAA | |
| SCHEMBL38662629 | 0.81 | TNF (0.41) | TNFRPS6KA3GAANPC1RAB9A | |
| SCHEMBL30350188 | 0.81 | CDC25B (0.50) | RPS6KA3GAAGSK3BTP53SMN1; SMN2 | |
| SCHEMBL2942923 | 0.81 | CDC25B (0.50) | RPS6KA3GAAGSK3BTP53SMN1; SMN2 | |
| SCHEMBL2947499 | 0.80 | LIMK1 (0.54) | CYP2A6NPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL21692174 | 0.79 | RPS6KA3 (0.59) | CYP2A6TNFNOTUMRPS6KA3AURKA | |
| SCHEMBL21692148 | 0.79 | RPS6KA3 (0.59) | CYP2A6TNFNOTUMRPS6KA3AURKA | |
| SCHEMBL8716812 | 0.79 | RPS6KA3 (0.65) | CYP2A6TNFNOTUMRPS6KA3AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120058670-A | Cyclic azine compound, material for organic electroluminescent element, electron transport material for organic electroluminescent element, and organic electroluminescent element | 东曹株式会社 | 2025-05-30 | — | — | CN | disclosed |
| CN-114096528-B | Cyclic azine compound, material for organic electroluminescent element, electron transport material for organic electroluminescent element, and organic electroluminescent element | 东曹株式会社 | 2025-03-21 | — | — | CN | disclosed |
| US-20230403927-A1 | AROMATIC COMPOUNDS | UDC IRELAND LTD (IE) | 2023-12-14 | — | — | US | disclosed |
| US-20230403927-A1 | AROMATIC COMPOUNDS | UDC IRELAND LTD (IE) | 2023-12-14 | — | — | US | disclosed |
| US-11800787-B2 | Metal complexes | UDC IRELAND LIMITED (IE) | 2023-10-24 | — | — | US | disclosed |
| US-11800787-B2 | Metal complexes | UDC IRELAND LIMITED (IE) | 2023-10-24 | — | — | US | disclosed |
| US-20230061841-A1 | SHMT INHIBITORS AND USES THEREOF | RAZE THERAPEUTICS, INC. | 2023-03-02 | — | — | US | disclosed |
| US-11588114-B2 | Organic molecules for use in optoelectronic devices | SAMSUNG DISPLAY CO., LTD. (KR) | 2023-02-21 | — | — | US | disclosed |
| US-20220274952-A1 | CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC LIGHT EMITTING DIODE, ELECTRON TRANSPORT MATERIAL FOR ORGANIC LIGHT EMITTING DIODE, AND ORGANIC LIGHT EMITTING DIODE | TOSOH CORPORATION (JP) | 2022-09-01 | — | — | US | disclosed |
| EP-4006023-A1 | CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ELECTRON TRANSPORT MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT | Tosoh Corporation (JP) | 2022-06-01 | — | — | EP | disclosed |
| CN-1308310-C | Nitrogen-containing aromatic ring derivatives | EISAI CO LTD (JP) | 2007-04-04 | — | — | CN | disclosed |
| US-20060247259-A1 | Urea derivatives containing aromatic or heteroaromatic rings; 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide; prophylactic or therapeutic agent for a disease for which angiogenesis inhibition is effective | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2006-11-02 | — | — | US | disclosed |
| EP-1270582-B1 | TRIPHENYLPHOSPHINE DERIVATIVES, PALLADIUM OR NICKEL COMPLEXES THEREOF, AND PROCESS FOR PREPARING BIARYL DERIVATIVES | MITSUBISHI RAYON CO (JP) | 2006-08-30 | — | — | EP | disclosed |
| US-20060160832-A1 | Urea derivatives containing aromatic or heteroaromatic rings; 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide; prophylactic or therapeutic agent for a disease for which angiogenesis inhibition is effective | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2006-07-20 | — | — | US | disclosed |
| EP-1506962-A2 | Nitrogen-containing aromatic heterocycles | Eisai Co. Ltd. (JP) | 2005-02-16 | — | — | EP | disclosed |
| EP-1415987-A1 | NITROGENOUS AROMATIC RING COMPOUNDS | Eisai Co., Ltd. (JP) | 2004-05-06 | — | — | EP | disclosed |
| US-20040053908-A1 | Urea derivatives containing aromatic or heteroaromatic rings, useful as prophylactic or therapeutic agent for a disease for which angiogenesis inhibition is effective | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2004-03-18 | — | — | US | disclosed |
| US-6693210-B2 | USING PALLADIUM, NICKEL PHOSPHINE COMPLEX AS CATALYSTS | MITSUBISHI RAYON CO., LTD. (JP) | 2004-02-17 | — | — | US | disclosed |
| US-20030065208-A1 | Using palladium, nickel phosphine complex as catalysts | MITSUBISHI RAYON CO., LTD. (JP) | 2003-04-03 | — | — | US | disclosed |
| EP-1270582-A1 | TRIPHENYLPHOSPHINE DERIVATIVE, PRODUCTION PROCESS THEREFOR, PALLADIUM COMPLEX THEREOF, AND PROCESS FOR PRODUCING BIARYL DERIVATIVE | Mitsubishi Rayon Co., Ltd. (JP) | 2003-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040053908-A1 | Urea derivatives containing aromatic or heteroaromatic rings, useful as prophylactic or therapeutic agent for a disease for which angiogenesis inhibition is effective | VEGFA, UACA, UTS2R | CYP2A6 760/4885TNF 1862/4885NOTUM 4546/4885 |
| US-20230403927-A1 | AROMATIC COMPOUNDS | TYR, CTCF, MITF | CYP2A6 1932/4885TNF 4698/4885NOTUM 3389/4885 |
| US-20060247259-A1 | Urea derivatives containing aromatic or heteroaromatic rings; 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide; prophylactic or therapeutic agent for a disease for which angiogenesis inhibition is effective | UGGT1, FLT1, GCG | CYP2A6 1579/4885TNF 3103/4885NOTUM 4520/4885 |
| US-20230061841-A1 | SHMT INHIBITORS AND USES THEREOF | SHMT1, SHMT2, BHMT | CYP2A6 2205/4885TNF 4465/4885NOTUM 1180/4885 |
| US-20030065208-A1 | Using palladium, nickel phosphine complex as catalysts | PDCD1LG2, PIK3CA, PDCD1 | CYP2A6 3190/4885TNF 3655/4885NOTUM 226/4885 |
| US-20220274952-A1 | CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC LIGHT EMITTING DIODE, ELECTRON TRANSPORT MATERIAL FOR ORGANIC LIGHT EMITTING DIODE, AND ORGANIC LIGHT EMITTING DIODE | AZI2, OXA1L, TMEM109 | CYP2A6 1637/4885TNF 1515/4885NOTUM 1818/4885 |
| US-11800787-B2 | Metal complexes | AP1M1, SOD1, AP3M1 | CYP2A6 3998/4885TNF 4846/4885NOTUM 3399/4885 |
| US-11588114-B2 | Organic molecules for use in optoelectronic devices | OR10J3, OPRM1, OR51E2 | CYP2A6 696/4885TNF 3330/4885NOTUM 1611/4885 |
| US-20060160832-A1 | Urea derivatives containing aromatic or heteroaromatic rings; 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide; prophylactic or therapeutic agent for a disease for which angiogenesis inhibition is effective | UGGT1, FLT1, GCG | CYP2A6 1579/4885TNF 3103/4885NOTUM 4520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.