Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.51 |
| ▸ | NT5E | P21589 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CASP6 | P55212 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.44 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | DUSP5 | Q16690 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31274741 | 0.90 | NT5E (0.57) | PTPN1NT5EALDH1A1HSD17B10CASP6 | |
| SCHEMBL591402 | 0.90 | NT5E (0.57) | PTPN1NT5EALDH1A1HSD17B10CASP6 | |
| Water SCHEMBL29461458 | 0.89 | NT5E (0.55) | PTPN1NT5EALDH1A1HSD17B10CASP6 | |
| Water SCHEMBL29259108 | 0.89 | NT5E (0.55) | PTPN1NT5EALDH1A1HSD17B10CASP6 | |
| SCHEMBL2730685 | 0.88 | PTPN1 (0.52) | PTPN1NT5EALDH1A1HSD17B10CASP6 | |
| SCHEMBL152377 | 0.86 | NT5E (0.68) | NT5EALDH1A1HSD17B10CASP6CYP2C9 | |
| SCHEMBL11426413 | 0.86 | NT5E (0.68) | NT5EALDH1A1HSD17B10CASP6CYP2C9 | |
| SCHEMBL31229304 | 0.86 | NT5E (0.68) | NT5EALDH1A1HSD17B10CASP6CYP2C9 | |
| SCHEMBL2730688 | 0.86 | NT5E (0.68) | NT5EALDH1A1HSD17B10CASP6CYP2C9 | |
| SCHEMBL30566330 | 0.86 | NT5E (0.68) | NT5EALDH1A1HSD17B10CASP6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10468701-B2 | Multi-acid polymers from multifunctional amino acids and sulfonyl halide precursors and methods of making the same | NISSAN NORTH AMERICA, INC. (US) | 2019-11-05 | — | — | US | claimed |
| US-20170279145-A1 | MULTI-ACID POLYMERS FROM MULTIFUNCTIONAL AMINO ACIDS AND SULFONYL HALIDE PRECURSORS AND METHODS OF MAKING THE SAME | NISSAN MOTOR CO., LTD. (JP) | 2017-09-28 | — | — | US | claimed |
| US-10468701-B2 | Multi-acid polymers from multifunctional amino acids and sulfonyl halide precursors and methods of making the same | NISSAN NORTH AMERICA, INC. (US) | 2019-11-05 | — | — | US | disclosed |
| US-20170279144-A1 | MULTI-ACID POLYMERS FROM MULTIFUNCTIONAL AMINO ACIDS AND SULFONYL HALIDE PRECURSORS AND METHODS OF MAKING THE SAME | NISSAN MOTOR CO., LTD. (JP) | 2017-09-28 | — | — | US | disclosed |
| US-20170279145-A1 | MULTI-ACID POLYMERS FROM MULTIFUNCTIONAL AMINO ACIDS AND SULFONYL HALIDE PRECURSORS AND METHODS OF MAKING THE SAME | NISSAN MOTOR CO., LTD. (JP) | 2017-09-28 | — | — | US | disclosed |
| US-20170274369-A1 | Multi-Acid Polymers and Methods of Making the Same | NISSAN MOTOR CO., LTD. (JP) | 2017-09-28 | — | — | US | disclosed |
| US-20170274368-A1 | MULTI-ACID POLYMERS AND METHODS OF MAKING THE SAME | NISSAN MOTOR CO., LTD. (JP) | 2017-09-28 | — | — | US | disclosed |
| US-9694357-B1 | Multi-acid polymers and methods of making the same | NISSAN NORTH AMERICA, INC. (US) | 2017-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170274368-A1 | MULTI-ACID POLYMERS AND METHODS OF MAKING THE SAME | FRS2, FXR2, PFAS | THRB 2629/4885PTPN1 347/4885NT5E 4795/4885 |
| US-20170274369-A1 | Multi-Acid Polymers and Methods of Making the Same | FRS2, PFAS, SOS2 | THRB 2919/4885PTPN1 687/4885NT5E 4795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.