SCHEMBL1921360

SCHEMBL1921360

O=P([O-])([O-])Oc1cc2cc(Br)c(Cl)cc2[nH]1.[Na+].[Na+]

nearest known ligand 0.39

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29770319 1.00 CSNK2A1 (0.39) CSNK2A1
SCHEMBL28351736 0.85 CSNK2A1 (0.39) CSNK2A1
SCHEMBL7749525 0.72 DAO (0.31)
SCHEMBL29377568 0.72 DAO (0.31)
SCHEMBL28281829 0.69 GPR84 (0.43)
SCHEMBL1921362 0.69 CSNK2A1 (0.43) CSNK2A1
Phosphoric Acid SCHEMBL28462485 0.67 CSNK2A1 (0.73) CSNK2A1
SCHEMBL17351236 0.66 CSNK2A1 (0.48) CSNK2A1
SCHEMBL14889487 0.66 CSNK2A1 (0.48) CSNK2A1
SCHEMBL28664360 0.65 DAO (0.56) CSNK2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 206 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4246147-B1 METHOD FOR MEASURING STEROL IN LIPOPROTEIN, AND REAGENT FOR MEASURING STEROL IN LIPOPROTEIN SYSMEX CORP (JP) 2026-05-06 EP disclosed
EP-3855182-B1 METHOD FOR OBTAINING INFORMATION ON COGNITIVE FUNCTION SYSMEX CORP (JP) 2026-04-29 EP disclosed
EP-3779457-B1 METHOD AND REAGENT FOR MEASURING UPTAKE PERFORMANCE OF LIPOPROTEIN SYSMEX CORP (JP) 2026-04-29 EP disclosed
EP-4047017-B1 MONOCLONAL ANTIBODY, MEASUREMENT REAGENT FOR CYTOKERATIN 18 FRAGMENT, REAGENT KIT, AND MEASUREMENT METHOD SYSMEX CORP (JP) 2026-03-04 EP disclosed
EP-3809135-B1 METHOD AND REAGENT FOR MEASURING LIPOPROTEIN'S UPTAKE ABILITY SYSMEX CORP (JP) 2026-01-14 EP disclosed
EP-4623995-A1 MONOCLONAL ANTIBODY, REAGENT FOR MEASURING CRTAC1B, REAGENT KIT, AND METHOD FOR MEASURING CRTAC1B SYSMEX CORPORATION (JP) 2025-10-01 EP disclosed
US-20250296994-A1 MONOCLONAL ANTIBODY, REAGENT FOR MEASURING CRTAC1B, REAGENT KIT, AND METHOD FOR MEASURING CRTAC1B SYSMEX CORPORATION (JP) 2025-09-25 US disclosed
US-12422429-B2 Methods for reducing noise in signal-generating digital assays ABBOTT JAPAN LLC (JP) 2025-09-23 US disclosed
EP-3798000-B1 LIQUID-SEALED CARTRIDGE AND LIQUID SENDING METHOD SYSMEX CORP (JP) 2025-07-23 EP disclosed
EP-3699593-B1 METHOD FOR ACQUIRING INFORMATION ON ANALYTE SYSMEX CORP (JP) 2025-06-18 EP disclosed
US-20170205428-A1 METHOD FOR DETECTING CARDIAC FAILURE PATIENT MATSUMORI AKIRA (JP) 2017-07-20 US disclosed
EP-3141906-A1 IMMUNE MEASURING APPARATUS AND IMMUNE MEASURING METHOD SYSMEX CORPORATION (JP) 2017-03-15 EP disclosed
US-20170059562-A1 IMMUNE MEASURING APPARATUS AND IMMUNE MEASURING METHOD SYSMEX CORPORATION (JP) 2017-03-02 US disclosed
EP-2950099-A1 PRETREATMENT METHOD FOR SAMPLE FOR DETECTING HBS ANTIGEN, AND USE THEREFOR Sysmex Corporation (JP) 2015-12-02 EP disclosed
US-20150330982-A1 PRETREATMENT METHOD OF SAMPLE FOR DETECTING HBS ANTIGEN AND USE THEREOF SYSMEX CORPORATION (JP) 2015-11-19 US disclosed
EP-2327987-B1 Method and kit for detection of HCV core protein SYSMEX CORP (JP) 2013-08-21 EP disclosed
US-8492166-B2 Particle suspension and reagent kit for use in immunoassay SYSMEX CORPORATION (JP) 2013-07-23 US disclosed
US-20110129815-A1 METHOD FOR PRETREATING SAMPLE FOR DETECTION HCV CORE PROTEIN, REAGENT KIT FOR DETECTION OF HCV CORE PROTEIN, METHOD FOR DETERMINING THE PRESENCE OR ABSENCE OF HEPATITIS C VIRUS IN SAMPLE, AND METHOD FOR IMMUNOASSAY OF HCV SYSMEX CORPORATION (JP) 2011-06-02 US disclosed
EP-2327987-A2 Method for pretreating sample for detection of HCV core protein, reagent kit for detection of HCV core protein, method for determining the presence or absence of hepatitis C virus in sample, and method for immunoassay of HCV SYSMEX CORPORATION (JP) 2011-06-01 EP disclosed
US-20110053176-A1 PARTICLE SUSPENSION AND REAGENT KIT FOR USE IN IMMUNOASSAY SYSMEX CORPORATION (JP) 2011-03-03 US disclosed