SCHEMBL1921362

SCHEMBL1921362

O=P([O-])([O-])Oc1c[nH]c2cc(Cl)c(Br)cc12.[Na+].[Na+]

nearest known ligand 0.43

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 2/20 0.43
CYP1A2 P05177 1/20 0.30
GSK3B P49841 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29351558 0.85 CSNK2A1 (0.43) CSNK2A1CYP1A2GSK3B
SCHEMBL307261 0.85 CSNK2A1 (0.43) CSNK2A1CYP1A2GSK3B
SCHEMBL5175862 0.83 CSNK2A1 (0.42) CSNK2A1CYP1A2GSK3B
Phosphoric Acid SCHEMBL5423551 0.76 CSNK2A1 (0.39) CSNK2A1CYP1A2GSK3B
SCHEMBL6930060 0.76 CSNK2A1 (0.46) CSNK2A1CYP1A2GSK3B
SCHEMBL3144514 0.76 GPR84 (0.46) CSNK2A1CYP1A2GSK3B
SCHEMBL28020005 0.76 F7 (0.47)
SCHEMBL3144513 0.76 GPR84 (0.46) GSK3B
SCHEMBL30712037 0.74 PRKAB2 (0.37) CSNK2A1
SCHEMBL6930062 0.73 SLC22A6 (0.51) CSNK2A1CYP1A2GSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 209 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9090929-B2 Medium for detecting and differentiating vancomycin-resistant enterococci OXOID LIMITED (GB) 2015-07-28 US claimed
EP-2186906-B1 Medium for detecting and differentiating vancomycin-resistant enterococci OXOID LTD (GB) 2012-07-25 EP claimed
EP-2186906-A2 Medium for detecting and differentiating vancomycin-resistant enterococci OXOID LIMITED (GB) 2010-05-19 EP claimed
US-20100120086-A1 MEDIUM FOR DETECTING AND DIFFERENTIATING VANCOMYCIN-RESISTANT ENTEROCOCCI OXOID LTD. (GB) 2010-05-13 US claimed
EP-4246147-B1 METHOD FOR MEASURING STEROL IN LIPOPROTEIN, AND REAGENT FOR MEASURING STEROL IN LIPOPROTEIN SYSMEX CORP (JP) 2026-05-06 EP disclosed
EP-3855182-B1 METHOD FOR OBTAINING INFORMATION ON COGNITIVE FUNCTION SYSMEX CORP (JP) 2026-04-29 EP disclosed
EP-3779457-B1 METHOD AND REAGENT FOR MEASURING UPTAKE PERFORMANCE OF LIPOPROTEIN SYSMEX CORP (JP) 2026-04-29 EP disclosed
CN-121896315-A Chromogenic medium for detecting staphylococcus aureus, preparation method thereof and test piece 广州热泉科技有限公司 2026-04-21 CN disclosed
EP-4047017-B1 MONOCLONAL ANTIBODY, MEASUREMENT REAGENT FOR CYTOKERATIN 18 FRAGMENT, REAGENT KIT, AND MEASUREMENT METHOD SYSMEX CORP (JP) 2026-03-04 EP disclosed
US-20260036584-A1 COMPOSITIONS AND METHODS TO DETECT GASTROINTESTINAL DISEASE THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIV AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2026-02-05 US disclosed
EP-3809135-B1 METHOD AND REAGENT FOR MEASURING LIPOPROTEIN'S UPTAKE ABILITY SYSMEX CORP (JP) 2026-01-14 EP disclosed
EP-4623995-A1 MONOCLONAL ANTIBODY, REAGENT FOR MEASURING CRTAC1B, REAGENT KIT, AND METHOD FOR MEASURING CRTAC1B SYSMEX CORPORATION (JP) 2025-10-01 EP disclosed
EP-2186906-A2 Medium for detecting and differentiating vancomycin-resistant enterococci OXOID LIMITED (GB) 2010-05-19 EP disclosed
US-20100120086-A1 MEDIUM FOR DETECTING AND DIFFERENTIATING VANCOMYCIN-RESISTANT ENTEROCOCCI OXOID LTD. (GB) 2010-05-13 US disclosed
EP-0874240-B1 Enzyme-labeled immunoassay and device therefor FUJIREBIO KK (JP) 2002-07-31 EP disclosed
US-20010005585-A1 Enzyme-labeled immunoassay and device therefor FUJIREBIO INC. (JP) 2001-06-28 US disclosed
US-6251618-B1 REACTION OF INDOYL DERIVATIVE WITH ENZYME IN PRESENCE OF SPECIFIC FREE RADICAL COMPOUND AND/OR CHELATE COMPOUND REDUCES TIME REQUIRED FOR DEVELOPMENT FUJIREBIO INC. (JP) 2001-06-26 US disclosed
US-6221625-B1 ALLOWING A TEST SAMPLE TO REACT WITH AN ENZYME-LABELED REAGENT, ALLOWING A SUBSTRATE TO REACT WITH THE ENZYME TO FORM A SIGNAL, AND IMMOBILISING THE ENZYME-LABELED REAGENT, WITH THE PREVENTION OF A FURTHER SIGNAL FORMATION FUJIREBIO INC. (JP) 2001-04-24 US disclosed
US-5998156-A MEASURING ENZYME ACTIVITY USING ENZYME LABELED ANTIBODY OR ANTIGEN FUJIREBIO INC. (JP) 1999-12-07 US disclosed
EP-0874240-A1 Enzyme-labeled immunoassay and device therefor Fujirebio Inc. (JP) 1998-10-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260036584-A1 COMPOSITIONS AND METHODS TO DETECT GASTROINTESTINAL DISEASE SI, FABP2, VIP CSNK2A1 491/4885CYP1A2 3170/4885GSK3B 485/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.