Phthalic Acid

Phthalic Acid

SCHEMBL192152

O=C([O-])c1ccccc1C(=O)[O-].[H+].[Na+]

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Phthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 known ✓ P00918 6/20 0.55
CA4 known ✓ P22748 2/20 0.55
CA1 known ✓ P00915 5/20 0.40
CA12 known ✓ O43570 1/20 0.40
THRB known ✓ P10828 1/20 0.39
PTGS2 known ✓ P35354 1/20 0.39
ALDH1A1 P00352 5/20 0.68
KDM4E B2RXH2 4/20 0.68
HPGD P15428 3/20 0.68
ALOX15 P16050 1/20 0.48
NFKB1 P19838 2/20 0.46
MAPK1 P28482 2/20 0.46
BLM P54132 2/20 0.46
CYP2C19 P33261 1/20 0.46
POLB P06746 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
PKLR P30613 1/20 0.41
CES2 O00748 2/20 0.40
CES1 P23141 2/20 0.40
HMGB1 P09429 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalic Acid SCHEMBL49301 0.97 ALDH1A1 (0.64) ALDH1A1KDM4EHPGDCA2CA4
Phthalic Acid SCHEMBL8206690 0.97 ALDH1A1 (0.64) ALDH1A1KDM4EHPGDCA2CA4
Phthalic Acid SCHEMBL105218 0.97 ALDH1A1 (0.71) ALDH1A1KDM4EHPGDCA2CA4
Phthalic Acid SCHEMBL28409980 0.97 ALDH1A1 (0.71) ALDH1A1KDM4EHPGDCA2CA4
Phthalic Acid SCHEMBL15106042 0.95 ALDH1A1 (0.62) ALDH1A1KDM4EHPGDCA2CA4
Phthalic Acid SCHEMBL5279211 0.95 ALDH1A1 (0.62) ALDH1A1KDM4EHPGDCA2CA4
Phthalic Acid SCHEMBL486782 0.94 ALDH1A1 (0.61) ALDH1A1KDM4EHPGDCA2CA4
Phthalic Acid SCHEMBL2378712 0.94 ALDH1A1 (0.61) ALDH1A1KDM4EHPGDCA2CA4
Phthalic Acid SCHEMBL183233 0.94 ALDH1A1 (0.61) ALDH1A1KDM4EHPGDCA2CA4
Phthalic Acid SCHEMBL11703255 0.94 ALDH1A1 (0.61) ALDH1A1KDM4EHPGDCA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 644 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4739687-A1 STABLE PALIPERIDONE PALMITATE COMPOSITION USING THERMAL TREATMENT Eugia Pharma Specialities Limited (IN) 2026-05-13 EP claimed
CN-119880565-A Method for measuring total carbon, inorganic carbon and organic carbon content in titanium tetrachloride 攀西钒钛检验检测院 2025-04-25 CN claimed
CN-119800369-A Low-foam cleaning agent and preparation method thereof 南通科星化工股份有限公司 2025-04-11 CN claimed
CN-119708504-A Preparation method and application of nano organic titanium polymer and titanium-based high molecular alloy copolymer 陕西至强重防材料技术有限公司 2025-03-28 CN claimed
CN-119176584-B Preparation method of positive electrode material 深圳先进技术研究院 2025-02-18 CN claimed
EP-3965759-B1 A TABLET FORMULATION COMPRISING LERCANIDIPINE AND ENALAPRIL SANOVEL ILAC SANAYI VE TICARET AS (TR) 2025-02-12 EP claimed
CN-118367130-B Soft and hard carbon negative electrode active material of sodium ion battery, and preparation method and application thereof 山东石油化工学院 2025-01-21 CN claimed
WO-2025008726-A1 STABLE PALIPERIDONE PALMITATE COMPOSITION USING THERMAL TREATMENT EUGIA PHARMA SPECIALITIES LIMITED (IN) 2025-01-09 WO claimed
CN-119176584-A Preparation method of positive electrode material 深圳先进技术研究院 2024-12-24 CN claimed
WO-2024255157-A1 NON-DESTRUCTIVE FAST-CHARGING POSITIVE ELECTRODE MATERIAL BASED ON ULTRASMALL PARTICLE NAXFEYMZ(SO4)3, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 深圳先进技术研究院 2024-12-19 WO claimed
US-6372329-B1 FOR FORMING HIGH QUALITY MULTI-COLORED IMAGES WITH MINIMAL INTER-COLOR BLEEDING AND INK CRACKING USING PIGMENTED INKS ARKWRIGHT, INCORPORATED 2002-04-16 US claimed
US-5729265-A Recording paper and ink-jet recording process making use of the same CANON KABUSHIKI KAISHA (JP) 1998-03-17 US claimed
EP-0608800-B1 Recording paper and ink-jet recording process making use of the same CANON KK (JP) 1997-12-29 EP claimed
US-5648164-A FOR USE IN RECORDING MAKING USE OF A WATER-BASED RECORDING LIQUID CONTAINING A DYE WHICH VARIES FROM WATER-SOLUBLE TO WATER-INSOLUBLE ACCORDING TO CHANGE OF PH; PAPER SURFACE PH ADJUSTED CANON KABUSHIKI KAISHA (JP) 1997-07-15 US claimed
EP-0711325-A4 1996-05-22 EP claimed
EP-0711325-A1 A METHOD OF PREPARING BIODEGRADABLE MODIFIED-STARCH MOLDABLE PRODUCTS AND FILMS EVERCORN, INC. (US) 1996-05-15 EP claimed
WO-1995004083-A1 A METHOD OF PREPARING BIODEGRADABLE MODIFIED-STARCH MOLDABLE PRODUCTS AND FILMS EVERCORN, INC. (US) 1995-02-09 WO claimed
US-4854969-A Lithographic fountain solutions SUN CHEMICAL CORPORATION (US) 1989-08-08 US claimed
US-4346709-A Drug delivery devices comprising erodible polymer and erosion rate modifier ALZA CORPORATION (US) 1982-08-31 US claimed
US-4268694-A HYDROLYSIS OF TETRAHALOCYCLOHEXANONE FISONS LIMITED (GB) 1981-05-19 US claimed