Phthalic Acid

Phthalic Acid

SCHEMBL105218

O=C([O-])c1ccccc1C(=O)[O-].[Na+].[Na+]

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Phthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 known ✓ P00918 7/20 0.57
CA4 known ✓ P22748 2/20 0.57
CA1 known ✓ P00915 6/20 0.42
CA12 known ✓ O43570 1/20 0.42
ALDH1A1 P00352 5/20 0.71
KDM4E B2RXH2 4/20 0.71
HPGD P15428 3/20 0.71
ALOX15 P16050 1/20 0.50
NFKB1 P19838 1/20 0.47
MAPK1 P28482 1/20 0.47
CYP2C19 P33261 1/20 0.47
BLM P54132 1/20 0.47
POLB P06746 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
PKLR P30613 1/20 0.42
CES2 O00748 2/20 0.42
CES1 P23141 2/20 0.42
HMGB1 P09429 1/20 0.42
CA6 P23280 1/20 0.42
CA7 P43166 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalic Acid SCHEMBL28409980 1.00 ALDH1A1 (0.71) ALDH1A1KDM4EHPGDCA2CA4
Phthalic Acid SCHEMBL64136 0.97 ALDH1A1 (0.68) ALDH1A1KDM4EHPGDCA2CA4
Phthalic Acid SCHEMBL32678845 0.97 ALDH1A1 (0.68) ALDH1A1KDM4EHPGDCA2CA4
Phthalic Acid SCHEMBL32678846 0.97 ALDH1A1 (0.68) ALDH1A1KDM4EHPGDCA2CA4
Phthalic Acid SCHEMBL192152 0.97 ALDH1A1 (0.68) ALDH1A1KDM4EHPGDCA2CA4
Phthalic Acid SCHEMBL32678844 0.97 ALDH1A1 (0.68) ALDH1A1KDM4EHPGDCA2CA4
Phthalic Acid SCHEMBL4506080 0.94 ALDH1A1 (0.65) ALDH1A1KDM4EHPGDCA2CA4
Phthalic Acid SCHEMBL11233274 0.94 ALDH1A1 (0.65) ALDH1A1KDM4EHPGDCA2CA4
Phthalic Acid SCHEMBL3385753 0.94 ALDH1A1 (0.65) ALDH1A1KDM4EHPGDCA2CA4
Phthalic Acid SCHEMBL4351997 0.94 ALDH1A1 (0.64) ALDH1A1KDM4EHPGDCA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2978 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116283536-B Method for converting and extracting phthalic acid by using byproducts 河南永新化学股份有限公司 2026-05-15 CN claimed
CN-117797793-B Metal titanium-based titanium dioxide photo-anode and application thereof in photoelectrocatalysis degradation of organic pollutants 中国科学院大连化学物理研究所 2026-05-12 CN claimed
US-12522511-B2 Methods and systems for treatment of limestone to form vaterite ARELAC, INC. (US) 2026-01-13 US claimed
CN-120136074-A Preparation method of hard carbon negative electrode material of sodium ion battery 山东海化集团有限公司 2025-06-13 CN claimed
EP-3723760-B1 ONE STEP MILLING PROCESS FOR PREPARING MICRONIZED PALIPERIDONE ESTERS SpecGx LLC (US) 2025-06-11 EP claimed
CN-120015842-A Composite current collector, preparation method and application thereof, and negative-electrode-free sodium ion battery 深圳市晟钠新能源科技有限公司 2025-05-16 CN claimed
CN-120019108-A Additive for heat treated foamable polypropylene 弗纳技术股份有限公司 2025-05-16 CN claimed
CN-119880565-A Method for measuring total carbon, inorganic carbon and organic carbon content in titanium tetrachloride 攀西钒钛检验检测院 2025-04-25 CN claimed
CN-119751396-A Method for preparing chlorophthalic anhydride by continuous chlorination of plug flow 哈尔滨工业大学(威海) 2025-04-04 CN claimed
CN-119674076-A Negative electrode additive and preparation method and application thereof 江苏正力新能电池技术股份有限公司 2025-03-21 CN claimed
US-4978361-A PRETREATMENT WITH ALDEHYDE OR KETO-CARBOXYLIC ACID; TANNING; FINISH TANNING WITH CHROMIUM (III) SALT, ACID-BINDER AND AROMATIC 2+ CARBOXYLIC ACID HOECHST AKTIENGESELLSCHAFT (DE) 1990-12-18 US claimed
US-4834891-A ALKALI METAL PHTHALATE, GLASS DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JP) 1989-05-30 US claimed
EP-0102230-B1 NOVEL 6-NITROPROSTAGLANDIN DERIVATIVES, PROCESS FOR PRODUCTION THEREOF, AND USE THEREOF TEIJIN LIMITED (JP) 1987-04-29 EP claimed
US-4507468-A Method for purifying polyphenylene sulfide DAINIPPON INK AND CHEMICALS, INC. (JP) 1985-03-26 US claimed
EP-0048988-B1 METHOD FOR FORMING DECORATIVE COLORED STREAK PATTERNS ON THE SURFACE OF AN ALUMINUM SHAPED ARTICLE YOSHIDA KOGYO K.K. (JP) 1984-06-06 EP claimed
EP-0102230-A2 Novel 6-nitroprostaglandin derivatives, process for production thereof, and use thereof TEIJIN LIMITED (JP) 1984-03-07 EP claimed
US-4420378-A Method for forming decorative colored streak patterns on the surface of an aluminum shaped article YOSHIDA KOGYO K. K. (JP) 1983-12-13 US claimed
EP-0048988-A1 Method for forming decorative colored streak patterns on the surface of an aluminum shaped article YOSHIDA KOGYO K.K. (JP) 1982-04-07 EP claimed
US-4293683-A Method for making polyetherimides using carboxylic acid salts of alkali metals or zinc as catalysts GENERAL ELECTRIC COMPANY (US) 1981-10-06 US claimed
US-4048118-A ALKALI METAL SALT OF ORGANIC ACID, AMINE SALT OF PHYTIC ACID SHOWA DENKO K.K. (JA) 1977-09-13 US claimed