SCHEMBL1932306

SCHEMBL1932306

c1csc(N2CCOCC2)n1

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.53
RAB9A P51151 3/20 0.53
MEN1 O00255 2/20 0.47
AR P10275 4/20 0.46
LMNA P02545 1/20 0.45
HPGD P15428 1/20 0.43
GRM5 P41594 1/20 0.43
GRM1 Q13255 1/20 0.43
KMT2A Q03164 1/20 0.43
HSD17B10 Q99714 1/20 0.42
SLC6A7 Q99884 1/20 0.42
CYP1A1 P04798 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP1B1 Q16678 1/20 0.42
OGA O60502 1/20 0.42
PIK3CA P42336 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
PIK3R1 P27986 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12744187 0.93 NPC1 (0.48) NPC1RAB9AMEN1ARLMNA
SCHEMBL29102030 0.85
SCHEMBL160290 0.81 NPC1 (0.53) NPC1RAB9AMEN1HPGDGRM5
SCHEMBL15058848 0.81
Methane SCHEMBL27085490 0.79 NPC1 (0.51) NPC1RAB9AMEN1ARHPGD
SCHEMBL13711959 0.79 NPC1 (0.51) NPC1RAB9AMEN1ARHPGD
SCHEMBL233663 0.79 NPC1 (0.51) NPC1RAB9AMEN1ARHPGD
Bromide SCHEMBL6317924 0.79 NPC1 (0.51) NPC1RAB9AMEN1HPGDGRM5
SCHEMBL12744157 0.78 NPC1 (0.41) NPC1RAB9AMEN1HPGDGRM5
SCHEMBL5032 0.78 NPC1 (0.50) NPC1RAB9AMEN1HPGDGRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118922081-A Insect, acarina and nematode pest control 先正达农作物保护股份公司 2024-11-08 CN claimed
US-20240092780-A1 ADDUCTS AND DIMER COMPOUNDS SYNTHESIZED USING GK METHOD ANKH LIFE SCIENCES LIMITED (IE) 2024-03-21 US claimed
CN-110431138-A AR-V7 inhibitor HOFFMANN LA ROCHE 2019-11-08 CN claimed
US-20060252751-A1 3-Aminopyrrolidine derivaties as modulators of chemokine receptors INCYTE HOLDINGS CORPORATION 2006-11-09 US claimed
CN-1147493-C Oxazolo, thiazolo and selenazolo [4,5-C]-quinolin-4-amines and analoges thereof 3M 2004-04-28 CN claimed
CN-1320126-A Oxazolo, thiazolo and selenazolo [4, 5-C ] quinolin-4-amines and analogs thereof 3M INNOVATIVE PROPERTIES CO (US) 2001-10-31 CN claimed
US-20260116874-A1 HETEROAROMATIC INDOLESULFONAMIDES SEED THERAPEUTICS INC (US) 2026-04-30 US disclosed
EP-4704836-A1 HETEROAROMATIC INDOLESULFONAMIDES Seed Therapeutics, Inc (US) 2026-03-11 EP disclosed
US-20250376452-A1 17-Beta-Hydroxysteroid Dehydrogenase Type 13 Inhibitors and Methods of Use Thereof ENANTA PHARM INC (US) 2025-12-11 US disclosed
US-12384753-B2 17-beta-hydroxysteroid dehydrogenase type 13 inhibitors and methods of use thereof ENANTA PHARMACEUTICALS, INC. (US) 2025-08-12 US disclosed
CN-120192314-A Aryl heterocycle Kv1.3 inhibitor and preparation method and application thereof 上海深势唯思科技有限责任公司 2025-06-24 CN disclosed
EP-4554938-A1 TYROSINE KINASE 2 INHIBITORS AND USES THEREOF Biogen MA Inc. (US) 2025-05-21 EP disclosed
CN-115403704-B Process for producing latex composition for dip molding 锦湖石油化学株式会社 2024-12-20 CN disclosed
US-6790844-B2 MUSCLE RELAXANTS; ANTISEROTONINE AGENT EISAI CO., LTD (JP) 2004-09-14 US disclosed
CN-1147493-C Oxazolo, thiazolo and selenazolo [4,5-C]-quinolin-4-amines and analoges thereof 3M 2004-04-28 CN disclosed
US-20020013460-A1 Condensed pyridine compound EISAI CO., LTD 2002-01-31 US disclosed
US-6340759-B1 ANTISPASMODIC AGENTS EISAI CO., LTD. (JP) 2002-01-22 US disclosed
CN-1320126-A Oxazolo, thiazolo and selenazolo [4, 5-C ] quinolin-4-amines and analogs thereof 3M INNOVATIVE PROPERTIES CO (US) 2001-10-31 CN disclosed
EP-1020445-A1 FUSED PYRIDINE DERIVATIVES Eisai Co., Ltd. (JP) 2000-07-19 EP disclosed
WO-1995015955-A1 2,4-DIAMINOTHIAZOLES AND THEIR PRODUCTION BASF AKTIENGESELLSCHAFT (DE) 1995-06-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060252751-A1 3-Aminopyrrolidine derivaties as modulators of chemokine receptors CCR2, CXCR3, CCR5 NPC1 4033/4885RAB9A 1445/4885MEN1 4347/4885
US-20020013460-A1 Condensed pyridine compound MUSK, HTR1A, PAX3 NPC1 4578/4885RAB9A 2421/4885MEN1 786/4885
US-20250376452-A1 17-Beta-Hydroxysteroid Dehydrogenase Type 13 Inhibitors and Methods of Use Thereof HSD17B1, HSD17B13, HSD17B3 NPC1 472/4885RAB9A 3762/4885MEN1 3138/4885
US-20260116874-A1 HETEROAROMATIC INDOLESULFONAMIDES DCAF1, DCAF15, DDX39B NPC1 1637/4885RAB9A 2243/4885MEN1 4259/4885
US-12384753-B2 17-beta-hydroxysteroid dehydrogenase type 13 inhibitors and methods of use thereof HSD17B1, HSD17B13, HSD17B3 NPC1 472/4885RAB9A 3762/4885MEN1 3138/4885
US-20240092780-A1 ADDUCTS AND DIMER COMPOUNDS SYNTHESIZED USING GK METHOD DRD2, HNMT, DRD1 NPC1 2675/4885RAB9A 1429/4885MEN1 2440/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.