Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.63 |
| ▸ | CASP3 | P42574 | 3/20 | 0.62 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.62 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.62 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.62 |
| ▸ | CDK4 | P11802 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | PRKCG | P05129 | 1/20 | 0.44 |
| ▸ | PRKCB | P05771 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
| ▸ | PRKCH | P24723 | 1/20 | 0.44 |
| ▸ | PRKCI | P41743 | 1/20 | 0.44 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16297244 | 0.78 | CASP3 (0.77) | CASP3SENP8SENP7SENP6CDK4 | |
| SCHEMBL636416 | 0.77 | DNM1 (1.00) | DNM1CASP3SENP8SENP7SENP6 | |
| SCHEMBL9650871 | 0.77 | DNM1 (0.63) | DNM1CASP3SENP8SENP7SENP6 | |
| SCHEMBL755665 | 0.76 | MAPT (0.64) | DNM1CASP3SENP8SENP7SENP6 | |
| SCHEMBL8367302 | 0.75 | CDK4 (0.56) | DNM1CASP3SENP8SENP7SENP6 | |
| SCHEMBL395770 | 0.74 | ALDH1A1 (0.50) | POLBMAPTMEN1KMT2ATDP1 | |
| SCHEMBL8548036 | 0.73 | CDK4 (0.64) | CASP3SENP8SENP7SENP6CDK4 | |
| SCHEMBL23831113 | 0.72 | DNM1 (0.62) | DNM1CASP3SENP8SENP7SENP6 | |
| SCHEMBL19409875 | 0.72 | MAPT (0.61) | DNM1CDK4POLBMAPTMEN1 | |
| SCHEMBL19409879 | 0.71 | DNM1 (0.45) | DNM1CASP3SENP8SENP7SENP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170283366-A1 | Benzoquinone Derivatives For Treatment Of Cancer And Methods Of Making The Benzoquinone Derivatives | UNITED ARAB EMIRATES UNIVERSITY (AE) | 2017-10-05 | — | — | US | claimed |
| US-20170283366-A1 | Benzoquinone Derivatives For Treatment Of Cancer And Methods Of Making The Benzoquinone Derivatives | UNITED ARAB EMIRATES UNIVERSITY (AE) | 2017-10-05 | — | — | US | disclosed |
| US-20170283366-A1 | Benzoquinone Derivatives For Treatment Of Cancer And Methods Of Making The Benzoquinone Derivatives | UNITED ARAB EMIRATES UNIVERSITY (AE) | 2017-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170283366-A1 | Benzoquinone Derivatives For Treatment Of Cancer And Methods Of Making The Benzoquinone Derivatives | BRCA1, BBOX1, KMO | DNM1 1345/4885CASP3 883/4885SENP8 4770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.