SCHEMBL194850

SCHEMBL194850

[c]1cccc2cc3c(cc12)c1cc2ccccc2cc1c1cc2ccccc2cc31

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.36
HSD17B10 Q99714 3/20 0.36
HIF1A Q16665 1/20 0.36
CYP1B1 Q16678 1/20 0.36
NQO1 P15559 1/20 0.35
PI4KA P42356 1/20 0.34
PI4K2B Q8TCG2 1/20 0.34
PI4K2A Q9BTU6 1/20 0.34
PI4KB Q9UBF8 1/20 0.34
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
NQO2 P16083 1/20 0.31
CYP2A6 P11509 7/20 0.31
TDP1 Q9NUW8 2/20 0.31
TSHR P16473 1/20 0.31
KDM4E B2RXH2 1/20 0.31
GAA P10253 1/20 0.31
ALOX12 P18054 1/20 0.30
CYP1A2 P05177 2/20 0.30
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18221906 0.93 ALDH1A1 (0.39) ALDH1A1HSD17B10HIF1ACYP1B1NQO1
SCHEMBL510364 0.91 ALDH1A1 (0.39) ALDH1A1HSD17B10HIF1ACYP1B1NQO1
SCHEMBL21464320 0.90 ALDH1A1 (0.46) ALDH1A1HSD17B10HIF1ACYP1B1NQO1
SCHEMBL194896 0.88 ALDH1A1 (0.45) ALDH1A1HSD17B10HIF1ACYP1B1NQO1
SCHEMBL18832 0.86 ALDH1A1 (0.36) ALDH1A1HSD17B10HIF1ACA1CA2
SCHEMBL27813028 0.85 ALDH1A1 (0.46) ALDH1A1HSD17B10HIF1ACYP1B1NQO1
SCHEMBL15366695 0.84 ALDH1A1 (0.39) ALDH1A1HSD17B10HIF1ACA1CA2
SCHEMBL29033245 0.84 ALDH1A1 (0.39) ALDH1A1HSD17B10HIF1ACA1CA2
SCHEMBL28474556 0.84 ALDH1A1 (0.39) ALDH1A1HSD17B10HIF1ACA1CA2
SCHEMBL25147 0.84 ALDH1A1 (0.39) ALDH1A1HSD17B10HIF1ACA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1090 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11158814-B2 9,10-dihydro-acridine derivative, and preparation method and use thereof NINGBO LUMILAN ADVANCED MATERIALS CO., LTD (CN) 2021-10-26 US claimed
US-20200091437-A1 9,10-DIHYDRO-ACRIDINE DERIVATIVE, AND PREPARATION METHOD AND USE THEREOF NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2020-03-19 US claimed
US-10249824-B2 Condensed-cyclic compound and organic light-emitting diode comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2019-04-02 US claimed
US-20130187084-A1 DISPERSED SOLUTION OF CARBON NANOTUBES AND METHOD OF PREPARING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2013-07-25 US claimed
US-8481174-B2 Organic light-emitting compound of CIS-diarylethene derivatives, organic electroluminescent device using the same, and method of manufacturing the device SAMSUNG DISPLAY CO., LTD. (KR) 2013-07-09 US claimed
US-8119038-B2 Organic electrolyte solution comprising glycidyl ether compound and lithium battery employing the same SAMSUNG SDI CO., LTD. (KR) 2012-02-21 US claimed
US-8021764-B2 Phenylcarbazole-based compound and organic electroluminescent device employing the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2011-09-20 US claimed
US-8012605-B2 Organic light-emitting compound and organic electroluminescent device using the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2011-09-06 US claimed
US-7906227-B2 Indene derivative compound and organic light emitting device comprising the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2011-03-15 US claimed
US-7901793-B2 Organic light-emitting compound and organic light-emitting device containing the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2011-03-08 US claimed
US-20060134463-A1 Triarylamine-based compound for organic electroluminescent device and organic electroluminescent device employing the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2006-06-22 US claimed
US-20060115680-A1 Phenylcarbazole-based compound and organic electroluminescent device employing the same SAMSUNG DISPLAY CO., LTD. (KR) 2006-06-01 US claimed
EP-1661888-A1 Phenylcarbazole-based compound and organic electroluminescent device employing the same Samsung SDI Co., Ltd. (KR) 2006-05-31 EP claimed
EP-1521758-B1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2006-05-24 EP claimed
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. 2006-03-02 US claimed
EP-1521758-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION Exxonmobil Chemical Patents Inc. (US) 2005-04-13 EP claimed
WO-2004007509-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-01-22 WO claimed
US-6410166-B1 Organic electroluminescence device doping device and organic electroluminescence device FUTABA CORPORATION (JP) 2002-06-25 US claimed
US-5403936-A Irradiating organic optical material comprising oxazoline derivative with light KABUSHIKI KAISHA TOSHIBA (JP) 1995-04-04 US claimed
US-4756989-A Aluminum or silicon substrate, copolymer resist layer comprising vinyl aromatic, ethylenically unsaturated units ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1988-07-12 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11158814-B2 9,10-dihydro-acridine derivative, and preparation method and use thereof GAPVD1, DHX9, DHRS9 ALDH1A1 51/4885HSD17B10 135/4885HIF1A 2773/4885
US-20060115680-A1 Phenylcarbazole-based compound and organic electroluminescent device employing the same SLC7A5, SLC7A1, SLC43A1 ALDH1A1 1043/4885HSD17B10 1540/4885HIF1A 3924/4885
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization MLX, LOX, LMTK3 ALDH1A1 2181/4885HSD17B10 1640/4885HIF1A 1790/4885
US-20200091437-A1 9,10-DIHYDRO-ACRIDINE DERIVATIVE, AND PREPARATION METHOD AND USE THEREOF GAPVD1, DHX9, DHRS9 ALDH1A1 51/4885HSD17B10 135/4885HIF1A 2773/4885
US-10249824-B2 Condensed-cyclic compound and organic light-emitting diode comprising the same CRY1, CRY2, CCNT1 ALDH1A1 63/4885HSD17B10 1435/4885HIF1A 584/4885
US-20060134463-A1 Triarylamine-based compound for organic electroluminescent device and organic electroluminescent device employing the same TRPC1, SLC7A5, TRPC6 ALDH1A1 830/4885HSD17B10 613/4885HIF1A 4701/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.