Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29849280 | 1.00 | HPGD (0.60) | HPGDALDH1A1MAPTGAAPOLB | |
| SCHEMBL393318 | 0.85 | NR4A2 (0.51) | HPGDALDH1A1MAPTGAAPOLB | |
| SCHEMBL4577829 | 0.82 | NR4A2 (0.56) | HPGDALDH1A1MAPTGAAHTT | |
| SCHEMBL29773857 | 0.82 | NR4A2 (0.56) | HPGDALDH1A1MAPTGAAHTT | |
| SCHEMBL5985839 | 0.81 | ALDH1A1 (0.48) | HPGDALDH1A1MAPTGAAPOLB | |
| SCHEMBL861495 | 0.81 | PTPN2 (0.54) | HPGDALDH1A1MAPTGAAPOLB | |
| SCHEMBL2482051 | 0.81 | NR4A2 (0.54) | HPGDALDH1A1MAPTGAAHTT | |
| SCHEMBL4363906 | 0.81 | ABL1 (0.62) | ALDH1A1MAPTPOLBHTTKMT2A | |
| SCHEMBL30249436 | 0.81 | CYP4F2 (0.68) | HPGDALDH1A1MAPTRECQLHTT | |
| SCHEMBL320371 | 0.81 | CYP4F2 (0.68) | HPGDALDH1A1MAPTRECQLHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116874364-A | Preparation method of 5-bromo-2-chlorobenzoic acid | 四平欧凯科技有限公司 | 2023-10-13 | — | — | CN | claimed |
| CN-116554018-A | Resource recycling process for 5-bromo-2-chlorobenzoic acid refining waste | 江西邦浦医药化工有限公司 | 2023-08-08 | — | — | CN | claimed |
| US-12595239-B2 | Substituted isoxazoline derivatives | BASF SE (DE) | 2026-04-07 | — | — | US | disclosed |
| EP-4646403-A1 | NOVEL CARBOXAMIDE AND SULFONAMIDE PESTICIDAL COMPOUNDS | Syngenta Crop Protection AG (CH) | 2025-11-12 | — | — | EP | disclosed |
| EP-4291551-B1 | SUBSTITUTED ISOXAZOLINE DERIVATIVES | BASF SE (DE) | 2025-08-13 | — | — | EP | disclosed |
| CN-120192276-A | Phenyl amide derivative and preparation and application thereof | 顺毅股份有限公司 | 2025-06-24 | — | — | CN | disclosed |
| US-20240262799-A1 | ISOXAZOLE DERIVATIVES AS NUCLEAR RECEPTOR AGONISTS AND USES THEREOF | IL DONG PHARMACEUTICAL CO., LTD. (KR) | 2024-08-08 | — | — | US | disclosed |
| WO-2024146945-A1 | NOVEL CARBOXAMIDE AND SULFONAMIDE PESTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2024-07-11 | — | — | WO | disclosed |
| US-20240140917-A1 | SUBSTITUTED ISOXAZOLINE DERIVATIVES | BASF SE (DE) | 2024-05-02 | — | — | US | disclosed |
| US-11912674-B2 | Isoxazole derivatives as nuclear receptor agonists and uses thereof | IL DONG PHARMACEUTICAL CO., LTD. (KR) | 2024-02-27 | — | — | US | disclosed |
| EP-4291551-A1 | SUBSTITUTED ISOXAZOLINE DERIVATIVES | BASF SE (DE) | 2023-12-20 | — | — | EP | disclosed |
| US-20040214888-A1 | Carboxylic acid derivative and medicine comprising salt or ester of the same | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2004-10-28 | — | — | US | disclosed |
| EP-1085010-B1 | PHENYLACETYLENE DERIVATIVES AND AGRICULTURAL/HORTICULTURAL BACTERICIDES | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2004-03-10 | — | — | EP | disclosed |
| EP-1394147-A1 | CARBOXYLIC ACID DERIVATIVE AND MEDICINE COMPRISING SALT OR ESTER OF THE SAME | Eisai Co., Ltd. (JP) | 2004-03-03 | — | — | EP | disclosed |
| WO-2003093297-A2 | PROTEIN KINASE MODULATORS AND METHODS OF USE | EXELIXIS, INC. (US) | 2003-11-13 | — | — | WO | disclosed |
| WO-2003076397-A1 | AMINOALCOHOL DERIVATIVES AS BETA-3 ADRENERGIC RECEPTOR AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-09-18 | — | — | WO | disclosed |
| US-20030153570-A1 | Aryl triazines as LPAAT-SS inhibitors and uses thereof | CELL THERAPEUTICS, INC. (US) | 2003-08-14 | — | — | US | disclosed |
| WO-2003037346-A1 | 6-PHENYL-N-PHENYL-(1,3,5) -TRIAZINE-2,4-DIAMINE DERIVATIVES AND RELATED COMPOUNDS WITH LYSOPHPHOSPHATIDIC ACID ACYLTRANSFERASE BETA (LPAAT-BETA) INHIBITORY ACTIVITY FOR USE IN THE TREATMENT OF CANCER | CELL THERAPEUTICS, INC. (US) | 2003-05-08 | — | — | WO | disclosed |
| US-6313071-B1 | Phenylacetylene derivatives and agricultural/horticultural fungicides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2001-11-06 | — | — | US | disclosed |
| EP-1085010-A1 | PHENYLACETYLENE DERIVATIVES AND AGRICULTURAL/HORTICULTURAL BACTERICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2001-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12595239-B2 | Substituted isoxazoline derivatives | CBR3, ADRA2C, CYP4Z1 | HPGD 4809/4885ALDH1A1 854/4885MAPT 4617/4885 |
| US-20240140917-A1 | SUBSTITUTED ISOXAZOLINE DERIVATIVES | CYP4X1, PRDX5, PRDX1 | HPGD 2526/4885ALDH1A1 1168/4885MAPT 2561/4885 |
| US-20030153570-A1 | Aryl triazines as LPAAT-SS inhibitors and uses thereof | LPCAT3, LPCAT1, PLAAT2 | HPGD 2432/4885ALDH1A1 1286/4885MAPT 4127/4885 |
| US-20040214888-A1 | Carboxylic acid derivative and medicine comprising salt or ester of the same | GPR119, NR3C1, INSR | HPGD 2617/4885ALDH1A1 1626/4885MAPT 4765/4885 |
| US-20240262799-A1 | ISOXAZOLE DERIVATIVES AS NUCLEAR RECEPTOR AGONISTS AND USES THEREOF | NR1H4, NR1H3, NR1H2 | HPGD 534/4885ALDH1A1 1135/4885MAPT 3807/4885 |
| US-11912674-B2 | Isoxazole derivatives as nuclear receptor agonists and uses thereof | NR1H4, NR1H3, NR1H2 | HPGD 550/4885ALDH1A1 840/4885MAPT 4496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.