Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL19583160 | 0.94 | — | — | |
| SCHEMBL28911777 | 0.88 | TDP1 (0.37) | — | |
| SCHEMBL7185025 | 0.84 | — | — | |
| SCHEMBL5362663 | 0.79 | — | — | |
| SCHEMBL6536404 | 0.77 | MEN1 (0.35) | MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL3368673 | 0.73 | — | — | |
| SCHEMBL5022370 | 0.72 | ALDH1A1 (0.40) | MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL833093 | 0.72 | — | — | |
| Water SCHEMBL28816709 | 0.71 | — | — | |
| Water SCHEMBL19915258 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3229769-B1 | BETTER DECOLORATION OF KERATINIC FIBERS | HENKEL AG & CO KGAA (DE) | 2019-10-23 | — | — | EP | claimed |
| US-10179099-B2 | Decolorization of dyed keratin fibers | HENKEL AG & CO. KGAA (DE) | 2019-01-15 | — | — | US | claimed |
| US-20170326055-A1 | DECOLORIZATION OF DYED KERATIN FIBERS | HENKEL AG & CO. KGAA (DE) | 2017-11-16 | — | — | US | claimed |
| US-11077040-B2 | Emulsions for enhanced reductive decoloration of keratin fibers | HENKEL AG & CO. KGAA (DE) | 2021-08-03 | — | — | US | disclosed |
| US-10179099-B2 | Decolorization of dyed keratin fibers | HENKEL AG & CO. KGAA (DE) | 2019-01-15 | — | — | US | disclosed |
| US-20180147128-A1 | EMULSIONS FOR ENHANCED REDUCTIVE DECOLORATION OF KERATIN FIBERS | HENKEL AG & CO. KGAA (DE) | 2018-05-31 | — | — | US | disclosed |
| US-20170326055-A1 | DECOLORIZATION OF DYED KERATIN FIBERS | HENKEL AG & CO. KGAA (DE) | 2017-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10179099-B2 | Decolorization of dyed keratin fibers | KRT18, DDR1, DDR2 | MEN1 3958/4885ALDH1A1 1054/4885TSHR 1194/4885 |
| US-20170326055-A1 | DECOLORIZATION OF DYED KERATIN FIBERS | KRT18, DDR1, DDR2 | MEN1 3958/4885ALDH1A1 1054/4885TSHR 1194/4885 |
| US-20180147128-A1 | EMULSIONS FOR ENHANCED REDUCTIVE DECOLORATION OF KERATIN FIBERS | KRT18, PRKDC, CUTA | MEN1 4123/4885ALDH1A1 41/4885TSHR 4286/4885 |
| US-11077040-B2 | Emulsions for enhanced reductive decoloration of keratin fibers | KRT18, PRKDC, CUTA | MEN1 4123/4885ALDH1A1 41/4885TSHR 4286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.