Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.35 |
| ▸ | RORA | P35398 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | RORB | Q92753 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL196180 | 0.85 | NR1H2 (0.37) | NR1H2NR1H3ESR1ESR2NR1I2 | |
| SCHEMBL537935 | 0.80 | CA2 (0.36) | NR1H2NR1H3NR1I2RORARORC | |
| SCHEMBL28887744 | 0.79 | HSD17B10 (0.36) | ESR1ESR2NR1I2CA2CA1 | |
| SCHEMBL537975 | 0.78 | CA2 (0.33) | NR1H2NR1H3NR1I2RORARORC | |
| SCHEMBL30998871 | 0.77 | PSIP1 (0.34) | NR1H2NR1H3NR1I2RORARORC | |
| SCHEMBL28769788 | 0.72 | ALDH1A1 (0.35) | NR1H2NR1H3NR1I2CA9ALDH1A1 | |
| Trifluoromethanesulfonic Acid SCHEMBL3813931 | 0.71 | ACHE (0.43) | NR1H2NR1H3ESR1ESR2NR1I2 | |
| SCHEMBL2057888 | 0.69 | KEAP1 (0.35) | ESR1ESR2NR1I2CA2CA1 | |
| SCHEMBL14777968 | 0.69 | CA1 (0.32) | CA2CA1ALDH1A1 | |
| SCHEMBL28527 | 0.69 | CA1 (0.32) | CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240238771-A1 | SUPPORTED RARE EARTH CATALYSTS AND CATALYTIC CH BORYLATION OF HYDROCARBONS | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2024-07-18 | — | — | US | claimed |
| WO-2025046071-A1 | PROCESS FOR THE PRODUCTION OF ESTETROL INTERMEDIATES | ESTETRA SRL (BE) | 2025-03-06 | — | — | WO | disclosed |
| US-20240238771-A1 | SUPPORTED RARE EARTH CATALYSTS AND CATALYTIC CH BORYLATION OF HYDROCARBONS | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2024-07-18 | — | — | US | disclosed |
| US-11053273-B2 | Process for the production of estetrol intermediates | ESTETRA S.P.R.L. (BE) | 2021-07-06 | — | — | US | disclosed |
| US-11053274-B2 | Process for the production of estetrol intermediates | ESTETRA S.P.R.L. (BE) | 2021-07-06 | — | — | US | disclosed |
| EP-2714712-B1 | PROCESS FOR THE PRODUCTION OF ESTETROL INTERMEDIATES | ESTETRA SPRL (BE) | 2016-08-24 | — | — | EP | disclosed |
| EP-2764008-B1 | PROCESS FOR THE PRODUCTION OF ESTETROL | ESTETRA SPRL (BE) | 2016-08-17 | — | — | EP | disclosed |
| EP-2714710-B1 | PROCESS FOR THE PRODUCTION OF ESTETROL INTERMEDIATES | ESTETRA SPRL (BE) | 2016-04-06 | — | — | EP | disclosed |
| US-8987484-B2 | Process for the production of estetrol | ESTETRA S.P.R.L. (BE) | 2015-03-24 | — | — | US | disclosed |
| US-20140243539-A1 | Process for the Production of Estetrol | ESTETRA S.P.R.L. (BE) | 2014-08-28 | — | — | US | disclosed |
| US-8088883-B2 | Transition metal complex and process for producing conjugated aromatic compound using the transition metal complex | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-01-03 | — | — | US | disclosed |
| US-20110046336-A1 | TRANSITION METAL COMPLEX AND PROCESS FOR PRODUCING CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX | SUMITOMO CHEMICAL COMPANY, LIMITED | 2011-02-24 | — | — | US | disclosed |
| US-20100184978-A1 | BIPYRIDINE COMPOUND, TRANSITION METAL COMPLEX, AND METHOD FOR PRODUCTION OF CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-07-22 | — | — | US | disclosed |
| EP-2192124-A1 | TRANSITION METAL COMPLEX AND PROCESS FOR PRODUCING CONJUGATED AROMATIC COMPOUND WITH THE TRANSITION METAL COMPLEX | Sumitomo Chemical Company, Limited (JP) | 2010-06-02 | — | — | EP | disclosed |
| EP-2172470-A1 | BIPYRIDINE COMPOUND, TRANSITION METAL COMPLEX, AND METHOD FOR PRODUCTION OF CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX | Sumitomo Chemical Company, Limited (JP) | 2010-04-07 | — | — | EP | disclosed |
| US-6414160-B1 | REACTING 5-ALKOXY-2(3H)OXAZOLONE COMPOUND WITH ALDEHYDE COMPOUND IN PRESENCE OF LEWIS ACID CATALYST | UBE INDUSTRIES, LTD. (JP) | 2002-07-02 | — | — | US | disclosed |
| EP-1000937-A1 | PROCESS FOR PRODUCING 4-ALKOXYCARBONYL-2-OXAZOLIDINONE COMPOUNDS | UBE INDUSTRIES LIMITED (JP) | 2000-05-17 | — | — | EP | disclosed |
| EP-0350334-B1 | A process for producing fluorine-containing compounds | NIPPON MINING CO (JP) | 1993-10-27 | — | — | EP | disclosed |
| US-5126482-A | Process for producing fluorine-containing carboxylic acids | NIPPON MINING CO., LTD. (JP) | 1992-06-30 | — | — | US | disclosed |
| EP-0350334-A2 | A process for producing fluorine-containing compounds | NIKKO KYODO CO., LTD. (JP) | 1990-01-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11053273-B2 | Process for the production of estetrol intermediates | SULT1A1, DHCR7, SULT1E1 | NR1H2 38/4885NR1H3 29/4885ESR1 193/4885 |
| US-20110046336-A1 | TRANSITION METAL COMPLEX AND PROCESS FOR PRODUCING CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX | C9, C5, AP1M1 | NR1H2 3025/4885NR1H3 3117/4885ESR1 871/4885 |
| US-20140243539-A1 | Process for the Production of Estetrol | VKORC1L1, CYP46A1, DHCR7 | NR1H2 49/4885NR1H3 61/4885ESR1 103/4885 |
| US-20100184978-A1 | BIPYRIDINE COMPOUND, TRANSITION METAL COMPLEX, AND METHOD FOR PRODUCTION OF CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX | C9, C5, AP2M1 | NR1H2 2937/4885NR1H3 2930/4885ESR1 997/4885 |
| US-20240238771-A1 | SUPPORTED RARE EARTH CATALYSTS AND CATALYTIC CH BORYLATION OF HYDROCARBONS | HAO2, SCO2, SOD1 | NR1H2 547/4885NR1H3 246/4885ESR1 465/4885 |
| US-11053274-B2 | Process for the production of estetrol intermediates | DHCR7, POR, C1R | NR1H2 60/4885NR1H3 62/4885ESR1 114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.