Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28758397 | 0.80 | TSHR (0.39) | SLC6A2SLC6A4SLC6A3CYP3A4CYP2C19 | |
| SCHEMBL28599082 | 0.73 | RAPGEF4 (0.36) | SLC6A2SLC6A4SLC6A3CYP3A4CYP2C19 | |
| SCHEMBL20102176 | 0.71 | TSHR (0.35) | — | |
| SCHEMBL13406762 | 0.67 | L3MBTL1 (0.35) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11035532 | 0.66 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3530399 | 0.66 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3 | |
| Hydrogen Peroxide SCHEMBL10882706 | 0.66 | LDHA (0.39) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5163137 | 0.65 | RAPGEF4 (0.41) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27927634 | 0.65 | RAPGEF4 (0.41) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9686493 | 0.63 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9346755-B2 | Kinetic resolution | THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH, NEAR DUBLIN TRINITY COLLEGE, UNIVERSITY OF DUBLIN (IE) | 2016-05-24 | — | — | US | disclosed |
| EP-2509933-B1 | KINETIC RESOLUTION | PROVOST FELLOWS & SCHOLARS COLLEGE OF THE HOLY UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN (IE) | 2016-04-20 | — | — | EP | disclosed |
| US-20150073170-A1 | KINETIC RESOLUTION | The Provost, Fellows, Foundation Scholars, and the Other Members of the Board, of the College of the (IE) | 2015-03-12 | — | — | US | disclosed |
| US-8946429-B2 | Kinetic resolution | THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF THE BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH, NEAR DUBLIN (IE) | 2015-02-03 | — | — | US | disclosed |
| US-20120277437-A1 | KINETIC RESOLUTION | THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY (IE) | 2012-11-01 | — | — | US | disclosed |
| EP-2509933-A1 | KINETIC RESOLUTION | The Provost, Fellows, Foundation Scholars, & the other members of Board, of the College of the Holy & Undiv. Trinity of Queen Elizabeth near Dublin (IE) | 2012-10-17 | — | — | EP | disclosed |
| WO-2011070028-A1 | KINETIC RESOLUTION | THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH, NEAR DUBLIN (IE) | 2011-06-16 | — | — | WO | disclosed |
| EP-2332895-A1 | Kinetic Resolution | The Provost, Fellows and Scholars of the College of the Holy and Undivided Trinity of Queen Elizabeth near Dublin (IE) | 2011-06-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150073170-A1 | KINETIC RESOLUTION | SPR, ADH5, ADH1C | SLC6A2 1470/4885SLC6A4 1445/4885SLC6A3 780/4885 |
| US-20120277437-A1 | KINETIC RESOLUTION | SPR, ADH5, ADH1C | SLC6A2 1470/4885SLC6A4 1445/4885SLC6A3 780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.