Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 2/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | ITK | Q08881 | 5/20 | 0.44 |
| ▸ | AURKA | O14965 | 2/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3079936 | 0.76 | BCHE (0.40) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL5051826 | 0.76 | KDR (0.68) | RAB9AKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL10176240 | 0.75 | KDR (0.61) | RAB9AKDM4EMEN1ALDH1A1MAPT | |
| Benzene SCHEMBL27629233 | 0.74 | RAB9A (0.69) | RAB9AKDM4EMEN1ALDH1A1MAPT | |
| Methane SCHEMBL28704887 | 0.74 | KDR (0.66) | RAB9AKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL2353932 | 0.74 | METAP2 (0.47) | RAB9AKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL29727516 | 0.73 | KDR (0.60) | RAB9AKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL1812287 | 0.73 | NPC1 (0.54) | RAB9AKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL2203414 | 0.72 | MAOB (0.48) | RAB9AKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL1770412 | 0.72 | KDM4E (0.33) | RAB9AKDM4EMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160115166-A1 | PYRROLO[2, 1-F] [1,2,4]TRIAZINE DERIVATIVE AND USE THEREOF FOR TREATING TUMORS | PHARMABLOCK (NANJING) R&D CO. LTD. (CN) | 2016-04-28 | — | — | US | claimed |
| EP-2948433-A1 | LIPASE INHIBITORS | Technische Universität Graz (AT) | 2015-12-02 | — | — | EP | claimed |
| WO-2014114649-A1 | LIPASE INHIBITORS | TECHNISCHE UNIVERSITÄT GRAZ (AT) | 2014-07-31 | — | — | WO | claimed |
| US-20140206738-A1 | LIPASE INHIBITORS | Karl-Franzens-Universität Graz (AT) | 2014-07-24 | — | — | US | claimed |
| US-20130210883-A1 | LIPASE INHIBITORS | GRILLARI JOHANNES (AT) | 2013-08-15 | — | — | US | claimed |
| EP-0699194-B1 | 5-HT4 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 2006-11-29 | — | — | EP | claimed |
| CN-110400884-B | Organic light emitting device and method of manufacturing the same | 三星显示有限公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-117956827-A | Light-emitting device including heterocyclic compound, electronic apparatus, and heterocyclic compound | 三星显示有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-111683662-B | Substituted pyrimidine compounds, pharmaceutical compositions and methods of treatment | 陈志宏 | 2024-04-02 | — | — | CN | disclosed |
| CN-109970779-B | Condensed cyclic compound and organic light-emitting device including the same | 三星显示有限公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-117229287-A | Condensed cyclic compound and organic light-emitting device including the same | 三星显示有限公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-106046011-B | Condensed cyclic compound and organic light-emitting device including the same | 三星显示有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-115820243-A | Composition, layer including the composition, light emitting device including the composition, and electronic device including the light emitting device | 三星电子株式会社 | 2023-03-21 | — | — | CN | disclosed |
| US-20090209553-A1 | Arylpiperazine derivatives and uses thereof | ROCHE PALO ALTO LLC | 2009-08-20 | — | — | US | disclosed |
| US-20080064687-A1 | Novel thiourea derivatives and the pharmaceutical compositions containing the same | SUH YOUNG G | 2008-03-13 | — | — | US | disclosed |
| EP-1515983-A1 | ANTIBACTERIAL AMIDE MACROCYCLES | Bayer HealthCare AG (DE) | 2005-03-23 | — | — | EP | disclosed |
| EP-1514942-A1 | METHOD OF SEARCHING SUBSTANE HAVING ANTIDIABETIC ACTIVITY | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003106480-A1 | ANTIBACTERIAL AMIDE MACROCYCLES | BAYER HEALTHCARE AG (DE) | 2003-12-24 | — | — | WO | disclosed |
| EP-1053241-A1 | NOVEL DIMERIZING AGENTS, THEIR PRODUCTION AND USE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2000-11-22 | — | — | EP | disclosed |
| WO-1999041258-A1 | NOVEL DIMERIZING AGENTS, THEIR PRODUCTION AND USE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1999-08-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209553-A1 | Arylpiperazine derivatives and uses thereof | ADRA2C, AHR, CYP1A2 | RAB9A 2265/4885KDM4E 2021/4885MEN1 3850/4885 |
| US-20140206738-A1 | LIPASE INHIBITORS | LPL, LIPA, PNLIP | RAB9A 3634/4885KDM4E 4316/4885MEN1 4086/4885 |
| US-20130210883-A1 | LIPASE INHIBITORS | PNLIP, LPL, LIPC | RAB9A 4046/4885KDM4E 1702/4885MEN1 3701/4885 |
| US-20160115166-A1 | PYRROLO[2, 1-F] [1,2,4]TRIAZINE DERIVATIVE AND USE THEREOF FOR TREATING TUMORS | GLS2, GTF2F1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | RAB9A 4110/4885KDM4E 3063/4885MEN1 2095/4885 |
| US-20080064687-A1 | Novel thiourea derivatives and the pharmaceutical compositions containing the same | TRPV1, TRPA1, TAS2R5 | RAB9A 778/4885KDM4E 4511/4885MEN1 3770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.