SCHEMBL1971978

SCHEMBL1971978

[CH2]C(C)(C)C(C)CCCC

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 2/20 0.36
TSHR P16473 3/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
OPRM1 P35372 1/20 0.35
CA2 P00918 7/20 0.34
MAPK1 P28482 1/20 0.34
CA1 P00915 4/20 0.33
ALDH1A1 P00352 3/20 0.32
TDP1 Q9NUW8 1/20 0.32
CYP3A4 P08684 1/20 0.31
FDPS P14324 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1970771 0.92 OPRM1 (0.44) DNM1TSHROPRM1CA2CA1
SCHEMBL1972947 0.90 OPRM1 (0.42) DNM1TSHROPRM1CA2FDPS
SCHEMBL6632947 0.90 OPRM1 (0.42) DNM1TSHROPRM1CA2FDPS
SCHEMBL18894365 0.90 OPRM1 (0.42) DNM1TSHROPRM1CA2FDPS
SCHEMBL6467303 0.90 OPRM1 (0.42) DNM1TSHROPRM1CA2FDPS
SCHEMBL1971923 0.83
SCHEMBL11432874 0.80 CA2 (0.37) DNM1TSHRSMN1; SMN2OPRM1CA2
SCHEMBL17607707 0.79 LMNA (0.43) CYP3A4
SCHEMBL28871028 0.78 ALDH1A1 (0.33) TSHRALDH1A1TDP1CYP3A4
SCHEMBL28049429 0.78 CA2 (0.33) DNM1TSHRSMN1; SMN2OPRM1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103788256-A Preparation method of high-melt fluidity high-rigidity antishock polypropylene CHINA PETROLEUM & CHEMICAL 2014-05-14 CN claimed
US-11345680-B2 Method for producing bispyrrolidine compounds BASF SE (DE) 2022-05-31 US disclosed
CN-113557033-A Conjugates of pattern recognition receptor agonists 阿森迪斯药物肿瘤股份有限公司 2021-10-26 CN disclosed
US-11156619-B2 Fluorescent pH sensors and methods of preparing them ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2021-10-26 US disclosed
US-20200392115-A1 METHOD FOR PRODUCING BISPYRROLIDINE COMPOUNDS BASF SE (DE) 2020-12-17 US disclosed
EP-3713915-A1 METHOD FOR PRODUCING BISPYRROLIDINE COMPOUNDS BASF SE (DE) 2020-09-30 EP disclosed
WO-2019101568-A1 METHOD FOR PRODUCING BISPYRROLIDINE COMPOUNDS BASF SE (DE) 2019-05-31 WO disclosed
CN-105969543-B Flue dust cleaning agent after fire 江苏筑磊电子科技有限公司 2019-04-05 CN disclosed
WO-2018136794-A1 FLUORESCENT PH SENSORS AND METHODS OF PREPARING AND USING THEM ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2018-07-26 WO disclosed
US-9469662-B2 Process for preparing optically active biophosphinylalkanes BASF SE (DE) 2016-10-18 US disclosed
CN-105969543-A Smoke dust cleaning agent after fire hazards 江苏筑磊电子科技有限公司 2016-09-28 CN disclosed
CN-103788256-A Preparation method of high-melt fluidity high-rigidity antishock polypropylene CHINA PETROLEUM & CHEMICAL 2014-05-14 CN disclosed
EP-1913007-B1 PROCESS FOR PREPARING OPTICALLY ACTIVE DIPHOSPHANES BASF SE (DE) 2011-06-22 EP disclosed
CN-101522647-A Substituted azolin-2-yl-amino compounds BASF AG (DE) 2009-09-02 CN disclosed
US-20080242893-A1 Process for Preparing Optically Active Diphosphanes BASF AKTIENGESELLSCHAFT (DE) 2008-10-02 US disclosed
EP-1913007-A1 PROCESS FOR PREPARING OPTICALLY ACTIVE DIPHOSPHANES BASF SE (DE) 2008-04-23 EP disclosed
WO-2007012655-A1 PROCESS FOR PREPARING OPTICALLY ACTIVE DIPHOSPHANES BASF SE (DE) 2007-02-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200392115-A1 METHOD FOR PRODUCING BISPYRROLIDINE COMPOUNDS BBOX1, DHPS, BCKDK DNM1 2909/4885TSHR 4272/4885SMN1; SMN2 4453/4885
US-11345680-B2 Method for producing bispyrrolidine compounds BCKDK, BBOX1, DHPS DNM1 2924/4885TSHR 4288/4885SMN1; SMN2 3706/4885
US-11156619-B2 Fluorescent pH sensors and methods of preparing them PHF8, PHF6, H1-0 DNM1 737/4885TSHR 4538/4885SMN1; SMN2 3477/4885
US-20080242893-A1 Process for Preparing Optically Active Diphosphanes PHOSPHO1, DCTPP1, DCPS DNM1 57/4885TSHR 4357/4885SMN1; SMN2 4647/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.