Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG known ✓ | P37231 | 6/20 | 0.41 |
| ▸ | PTGS1 known ✓ | P23219 | 2/20 | 0.40 |
| ▸ | PTGS2 known ✓ | P35354 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.39 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.39 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7095329 | 0.87 | PPARG (0.43) | PPARGHTTPTGS1PTGS2GLA | |
| Methacrylic Acid SCHEMBL38651194 | 0.86 | TDP1 (0.44) | PPARGHTTGLATDP1KMT2A | |
| Methacrylic Acid SCHEMBL7732677 | 0.84 | GLA (0.43) | PPARGHTTPTGS1PTGS2GLA | |
| Butadiene SCHEMBL9342741 | 0.83 | HTT (0.39) | PPARGHTTGLATDP1KMT2A | |
| Methacrylic Acid SCHEMBL7729849 | 0.83 | HTT (0.42) | PPARGHTTPTGS1PTGS2GLA | |
| SCHEMBL2064222 | 0.83 | PPARG (0.52) | PPARGHTTKMT2ALMNANFE2L2 | |
| SCHEMBL4339905 | 0.83 | PPARG (0.52) | PPARGHTTKMT2ALMNANFE2L2 | |
| SCHEMBL98228 | 0.83 | PPARG (0.52) | PPARGHTTKMT2ALMNANFE2L2 | |
| Styrene SCHEMBL7949015 | 0.82 | ALDH1A1 (0.41) | PPARGHTTGLATDP1KMT2A | |
| SCHEMBL28223837 | 0.82 | PPARG (0.44) | PPARGHTTKMT2ALMNANFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110144264-A1 | PROCESS FOR PREPARING STABILIZED LATICES BY EMULSION POLYMERIZATION | COATEX | 2011-06-16 | — | — | US | claimed |
| EP-3851468-A1 | AQUEOUS POLYURETHANE RESIN COMPOSITION AND COATING MATERIAL USING THE COMPOSITION | Covestro Intellectual Property GmbH & Co. KG (DE) | 2021-07-21 | — | — | EP | disclosed |
| EP-2832754-B1 | VINYL RESIN AND RESIN COMPOSITION | SANYO CHEMICAL IND LTD (JP) | 2020-10-28 | — | — | EP | disclosed |
| US-20150119497-A1 | VINYL RESIN AND RESIN COMPOSITION | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2015-04-30 | — | — | US | disclosed |
| EP-2832754-A1 | VINYL RESIN AND RESIN COMPOSITION | Sanyo Chemical Industries, Ltd. (JP) | 2015-02-04 | — | — | EP | disclosed |
| CN-104203999-A | Vinyl resin and resin composition | SANYO CHEMICAL INDUSTRY LTD | 2014-12-10 | — | — | CN | disclosed |