Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26236505 | 0.87 | CYP3A4 (0.33) | DRD2DRD3 | |
| SCHEMBL19789695 | 0.87 | CYP3A4 (0.33) | DRD2DRD3 | |
| SCHEMBL19789808 | 0.64 | SLC10A2 (0.31) | — | |
| SCHEMBL19789663 | 0.64 | ALDH1A1 (0.32) | — | |
| SCHEMBL19789691 | 0.62 | KDM4E (0.39) | ADRA2AADRA2BADRA2C | |
| SCHEMBL14501784 | 0.61 | SIGMAR1 (0.46) | — | |
| SCHEMBL9776870 | 0.60 | DRD2 (0.68) | DRD2DRD3 | |
| SCHEMBL19789868 | 0.60 | HTR1A (0.36) | ADRA2AADRA2BADRA2CCYP26A1DRD2 | |
| SCHEMBL11745042 | 0.59 | ADRA2A (0.43) | ADRA2AADRA2BADRA2CCYP26A1 | |
| SCHEMBL14596264 | 0.59 | HTR2A (0.37) | ADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2282991-B1 | METHOD FOR THE PRODUCTION OF 1,4-BENZOTHIEPIN-1,1-DIOXIDE DERIVATIVES | SANOFI AVENTIS DEUTSCHLAND (DE) | 2018-01-24 | — | — | EP | disclosed |