Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.39 |
| ▸ | FDPS | P14324 | 3/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14848213 | 1.00 | TSHR (0.46) | TSHRTHRBLMNADNM1OPRM1 | |
| SCHEMBL8297041 | 1.00 | TSHR (0.46) | TSHRTHRBLMNADNM1OPRM1 | |
| SCHEMBL13601912 | 1.00 | TSHR (0.46) | TSHRTHRBLMNADNM1OPRM1 | |
| SCHEMBL15211724 | 1.00 | TSHR (0.46) | TSHRTHRBLMNADNM1OPRM1 | |
| SCHEMBL366647 | 1.00 | TSHR (0.46) | TSHRTHRBLMNADNM1OPRM1 | |
| SCHEMBL13475536 | 1.00 | TSHR (0.46) | TSHRTHRBLMNADNM1OPRM1 | |
| SCHEMBL24044418 | 1.00 | TSHR (0.46) | TSHRTHRBLMNADNM1OPRM1 | |
| SCHEMBL12844942 | 1.00 | TSHR (0.46) | TSHRTHRBLMNADNM1OPRM1 | |
| SCHEMBL985792 | 1.00 | TSHR (0.46) | TSHRTHRBLMNADNM1OPRM1 | |
| SCHEMBL4745188 | 1.00 | TSHR (0.46) | TSHRTHRBLMNADNM1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230371358-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2023-11-16 | — | — | US | disclosed |
| US-20230348510-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2023-11-02 | — | — | US | disclosed |
| US-20230312578-A1 | 6H-INDOLO[2,3-B]QUINOXALINE DERIVATIVES USEFUL IN THERAPY | VIRONOVA THIONATION AB (SE) | 2023-10-05 | — | — | US | disclosed |
| US-20230276691-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2023-08-31 | — | — | US | disclosed |
| US-20230200211-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2023-06-22 | — | — | US | disclosed |
| US-20210340147-A1 | 2,6-DIMETHYL-N-((PYRIDlN-4-YL)METHYL)IMIDAZO[1,2-B]PYRIDAZIN-8-AMINE AND 2,5-DIMETHYL-N-[(PYRIDlN-4-YL)METHYL]PYRAZOLO[1,5-A]PYRIMIDlN-7-AMINE DERIVATIVES FOR TREATING VIRAL INFECTIONS | CUROVIR AB (SE) | 2021-11-04 | — | — | US | disclosed |
| US-10407390-B2 | Asymmetric ureas and medical uses thereof | HELSINN HEALTHCARE SA | 2019-09-10 | — | — | US | disclosed |
| US-20180044293-A1 | ASYMMETRIC UREAS AND MEDICAL USES THEREOF | HELSINN HEALTHCARE SA (CH) | 2018-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210340147-A1 | 2,6-DIMETHYL-N-((PYRIDlN-4-YL)METHYL)IMIDAZO[1,2-B]PYRIDAZIN-8-AMINE AND 2,5-DIMETHYL-N-[(PYRIDlN-4-YL)METHYL]PYRAZOLO[1,5-A]PYRIMIDlN-7-AMINE DERIVATIVES FOR TREATING VIRAL INFECTIONS | NSUN2, EIF2AK2, METTL16 | TSHR 3851/4885THRB 2970/4885LMNA 568/4885 |
| US-20230200211-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | OCIAD2, OPRM1, OCIAD1 | TSHR 1460/4885THRB 3253/4885LMNA 701/4885 |
| US-10407390-B2 | Asymmetric ureas and medical uses thereof | UTS2R, GPR119, GHSR | TSHR 143/4885THRB 190/4885LMNA 3368/4885 |
| US-20230348510-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | LBR, OXER1, OXSR1 | TSHR 312/4885THRB 1645/4885LMNA 548/4885 |
| US-20180044293-A1 | ASYMMETRIC UREAS AND MEDICAL USES THEREOF | UTS2R, GPR119, GHSR | TSHR 143/4885THRB 190/4885LMNA 3368/4885 |
| US-20230312578-A1 | 6H-INDOLO[2,3-B]QUINOXALINE DERIVATIVES USEFUL IN THERAPY | IDH3B, IDH3A, IDH1 | TSHR 4219/4885THRB 2501/4885LMNA 3249/4885 |
| US-20230276691-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | MCOLN2, LOXL1, LOXL2 | TSHR 2455/4885THRB 2119/4885LMNA 377/4885 |
| US-20230371358-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | LIFR, SOD1, ROS1 | TSHR 189/4885THRB 1522/4885LMNA 2276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.