Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.38 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.38 |
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.34 |
| ▸ | P2RY4 known ✓ | P51582 | 3/20 | 0.33 |
| ▸ | P2RY2 known ✓ | P41231 | 1/20 | 0.33 |
| ▸ | P2RY12 known ✓ | Q9H244 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 3/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.36 |
| ▸ | DUSP5 | Q16690 | 1/20 | 0.34 |
| ▸ | PKLR | P30613 | 3/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | PGAM1 | P18669 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.33 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10674447 | 0.89 | ALDH1A1 (0.46) | CA1CA2F2PRSS1PRSS2 | |
| SCHEMBL9951727 | 0.87 | CA1 (0.39) | CA1CA2F2PRSS1PRSS2 | |
| SCHEMBL9950641 | 0.81 | FTO (0.38) | CA1CA2F2PRSS1PRSS2 | |
| SCHEMBL11661547 | 0.79 | DUSP5 (0.39) | CA1CA2F2PRSS1PRSS2 | |
| SCHEMBL11855494 | 0.76 | CYP3A4 (0.43) | CA1CA2PTGS1DUSP5PKLR | |
| SCHEMBL13277832 | 0.76 | CA1 (0.40) | CA1CA2F2PRSS1PRSS2 | |
| SCHEMBL29392002 | 0.76 | CA1 (0.63) | CA1CA2F2PRSS1PRSS2 | |
| SCHEMBL1648601 | 0.76 | CA1 (0.63) | CA1CA2F2PRSS1PRSS2 | |
| SCHEMBL9449375 | 0.76 | CA1 (0.63) | CA1CA2F2PRSS1PRSS2 | |
| SCHEMBL29653826 | 0.75 | MCL1 (0.52) | ALDH1A1TSHRMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3365168-B1 | LIGHTWEIGHT FLAME RETARDANT THERMOPLASTIC STRUCTURES | SCHNELLER LLC (US) | 2021-06-30 | — | — | EP | claimed |
| CN-108367529-B | Lightweight flame retardant thermoplastic structures | 施内勒公司 | 2021-02-05 | — | — | CN | claimed |
| EP-3365168-A1 | LIGHTWEIGHT FLAME RETARDANT THERMOPLASTIC STRUCTURES | Schneller, LLC (US) | 2018-08-29 | — | — | EP | claimed |
| WO-2017070276-A1 | LIGHTWEIGHT FLAME RETARDANT THERMOPLASTIC STRUCTURES | SCHNELLER LLC (US) | 2017-04-27 | — | — | WO | claimed |
| US-20170113445-A1 | LIGHTWEIGHT FLAME RETARDANT THERMOPLASTIC STRUCTURES | SCHNELLER LLC | 2017-04-27 | — | — | US | claimed |
| US-8975367-B2 | Polyphosphonate and copolyphosphonate additive mixtures | FRX POLYMERS, INC. (US) | 2015-03-10 | — | — | US | claimed |
| EP-3365168-B1 | LIGHTWEIGHT FLAME RETARDANT THERMOPLASTIC STRUCTURES | SCHNELLER LLC (US) | 2021-06-30 | — | — | EP | disclosed |
| CN-108367529-B | Lightweight flame retardant thermoplastic structures | 施内勒公司 | 2021-02-05 | — | — | CN | disclosed |
| US-20200338873-A1 | LIGHTWEIGHT FLAME RETARDANT THERMOPLASTIC STRUCTURES | SCHNELLER LLC (US) | 2020-10-29 | — | — | US | disclosed |
| EP-3365168-A1 | LIGHTWEIGHT FLAME RETARDANT THERMOPLASTIC STRUCTURES | Schneller, LLC (US) | 2018-08-29 | — | — | EP | disclosed |
| WO-2017070276-A1 | LIGHTWEIGHT FLAME RETARDANT THERMOPLASTIC STRUCTURES | SCHNELLER LLC (US) | 2017-04-27 | — | — | WO | disclosed |
| US-20170113445-A1 | LIGHTWEIGHT FLAME RETARDANT THERMOPLASTIC STRUCTURES | SCHNELLER LLC | 2017-04-27 | — | — | US | disclosed |
| US-9527984-B2 | Polyphosphonate and copolyphosphonate additive mixtures | FRX POLYMERS, INC. (US) | 2016-12-27 | — | — | US | disclosed |
| EP-2338924-A1 | POLYMER, POLYMER ELECTROLYTE AND USE OF SAME | Sumitomo Chemical Company, Limited (JP) | 2011-06-29 | — | — | EP | disclosed |
| US-20110151355-A1 | POLYMER, POLYMER ELECTROLYTE AND USE OF SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-06-23 | — | — | US | disclosed |
| EP-1497374-B1 | FILLER REINFORCED POLYETHER IMIDE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF | GEN ELECTRIC (US) | 2008-08-13 | — | — | EP | disclosed |
| US-7244778-B2 | Filler reinforced polyether imide resin composition and molded article thereof | GENERAL ELECTRIC COMPANY (US) | 2007-07-17 | — | — | US | disclosed |
| US-20050131105-A1 | Filler reinforced polyether imide resin composition and molded article thereof | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2005-06-16 | — | — | US | disclosed |
| EP-1497374-A1 | FILLER REINFORCED POLYETHER IMIDE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF | GENERAL ELECTRIC COMPANY (US) | 2005-01-19 | — | — | EP | disclosed |
| WO-2003087226-A1 | FILLER REINFORCED POLYETHER IMIDE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF | GENERAL ELECTRIC COMPAMY (US) | 2003-10-23 | — | — | WO | disclosed |