Fluoride

Fluoride

SCHEMBL1994686

F.F.F.F.[F-].[Na+].[SiH4]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Fluoride. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL378801 1.00
Fluoride SCHEMBL27532480 0.89
Fluoride Ion SCHEMBL1994685 0.87
Fluoride Ion SCHEMBL27480244 0.87
Fluoride SCHEMBL17766113 0.87 CA4 (0.33)
Fluoride SCHEMBL10382021 0.87 CA4 (0.33)
Fluoride SCHEMBL372354 0.87
Fluoride SCHEMBL29129531 0.87
Fluoride SCHEMBL10902089 0.75
Fluoride SCHEMBL6859065 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117511108-B Grafting modified low-protein natural latex sponge product and preparation method thereof 中国热带农业科学院南亚热带作物研究所 2024-08-09 CN claimed
CN-110218366-B Isoprene rubber/nano white carbon black composite material, vulcanized rubber, preparation method and application thereof 中国石油化工股份有限公司 2024-06-04 CN claimed
CN-118006069-A Plant essential oil-loaded microcapsule filling grafting modified low-protein natural latex sponge and preparation method thereof 中国热带农业科学院南亚热带作物研究所 2024-05-10 CN claimed
CN-117511108-A Grafting modified low-protein natural latex sponge product and preparation method thereof 中国热带农业科学院南亚热带作物研究所 2024-02-06 CN claimed
WO-2024025243-A1 ORAL COMPOSITION (주)메디클러스 2024-02-01 WO claimed
CN-116715200-A Recycling method of lithium hexafluorophosphate fluorine-containing tail gas 宜昌晶能富新材料有限公司 2023-09-08 CN claimed
CN-116396035-B Concrete for drain pipe and drain pipe 北京慕湖外加剂有限公司 2023-08-08 CN claimed
CN-116396035-A Concrete for drain pipe and drain pipe 北京慕湖外加剂有限公司 2023-07-07 CN claimed
CN-116120703-A Wear-resistant foaming material and preparation method thereof 莆田市华骏鞋业有限公司 2023-05-16 CN claimed
CN-109650481-A A kind of domestic sewage treating compound and preparation method thereof 武汉芳笛环保股份有限公司 2019-04-19 CN claimed
CN-101663018-B Teeth whitening functional materials delivery system SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) 2011-12-07 CN claimed
CN-101663018-A The transfer system of teeth whitening functional materials SEOUL NAT UNIV IND FOUNDATION 2010-03-03 CN claimed
EP-1189841-A4 CONTINUOUS CALCINATION OF MIXED METAL OXIDES FERRO CORP (US) 2007-04-11 EP claimed
EP-0947283-B1 A HIGH HARDNESS AND WEAR-RESISTING FLUX CORED WIRE PAN GUOXI (CN) 2002-07-17 EP claimed
US-20020073895-A1 Continuous calcination of mixed metal oxides FERRO CORPORATION 2002-06-20 US claimed
EP-1189841-A1 CONTINUOUS CALCINATION OF MIXED METAL OXIDES FERRO CORPORATION (US) 2002-03-27 EP claimed
WO-2000064813-A1 CONTINUOUS CALCINATION OF MIXED METAL OXIDES FERRO CORPORATION (US) 2000-11-02 WO claimed
US-6103997-A High hardness and wear-resisting flux cored wire PAN GUOXI (CN) 2000-08-15 US claimed
EP-0947283-A1 A HIGH HARDNESS AND WEAR-RESISTING FLUX CORED WIRE Pan, Guoxi (CN) 1999-10-06 EP claimed
US-4756896-A Reducing gaseous silicon tetrafluoride by alkali metal or alkaline earth metal dispersed into a liquid at 300 to 350 degrees KEMIRA OY (FI) 1988-07-12 US claimed