SCHEMBL19968564

SCHEMBL19968564

FC(F)(F)c1ccc(P(I)c2ccc(C(F)(F)F)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.43
TSHR P16473 1/20 0.43
KIF11 P52732 6/20 0.42
TRPV6 Q9H1D0 2/20 0.41
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
ORAI1 Q96D31 1/20 0.41
ORAI2 Q96SN7 1/20 0.41
ORAI3 Q9BRQ5 1/20 0.41
MGLL Q99685 1/20 0.41
TAAR1 Q96RJ0 1/20 0.38
EPHX2 P34913 1/20 0.37
HTR3E A5X5Y0 1/20 0.37
HTR3B O95264 1/20 0.37
PLAU P00749 1/20 0.37
HTR3A P46098 1/20 0.37
HTR3D Q70Z44 1/20 0.37
HTR3C Q8WXA8 1/20 0.37
IDO1 P14902 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL287478 0.78 ALDH1A1 (0.48) ALDH1A1TSHRKIF11TRPV6CES2
SCHEMBL15661104 0.78 ALDH1A1 (0.48) ALDH1A1TSHRKIF11TRPV6CES2
SCHEMBL63468 0.76 ALDH1A1 (0.67) ALDH1A1TSHRKIF11TRPV6CES2
SCHEMBL5713308 0.76 ALDH1A1 (0.46) ALDH1A1TSHRKIF11TRPV6CES2
SCHEMBL31325622 0.76 ALDH1A1 (0.46) ALDH1A1TSHRKIF11TRPV6CES2
SCHEMBL7526444 0.74 CES2 (0.46) ALDH1A1TSHRKIF11TRPV6CES2
SCHEMBL8654887 0.74 EPHX2 (0.46) ALDH1A1TSHRKIF11TRPV6CES2
Hydrochloric Acid SCHEMBL21724854 0.74 KIF11 (0.46) ALDH1A1TSHRKIF11TRPV6CES2
SCHEMBL2201199 0.74 ALDH1A1 (0.43) ALDH1A1TSHRKIF11TRPV6CES2
SCHEMBL669274 0.74 ALDH1A1 (0.43) ALDH1A1TSHRKIF11TRPV6CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113896607-B Olefin oligomerization process using a catalyst comprising a chromium complex having a phosphacycle-containing ligand 陶氏环球技术有限责任公司 2024-04-16 CN disclosed
US-20220176363-A1 PROCESS FOR OLIGOMERIZATION DOW GLOBAL TECHNOLOGIES LLC (US) 2022-06-09 US disclosed
CN-107548385-B Olefin oligomerization process using catalyst comprising chromium complex with phosphacycle-containing ligand 陶氏环球技术有限责任公司 2022-01-21 CN disclosed
CN-113896607-A Olefin oligomerization process using catalyst comprising chromium complex with phosphacycle-containing ligand 陶氏环球技术有限责任公司 2022-01-07 CN disclosed
CN-107592863-B Chromium complexes with ligands containing phosphacycles and olefin oligomerization catalysts therefrom 陶氏环球技术有限责任公司 2021-09-10 CN disclosed
CN-107567355-B Phosphacycle-containing ligands for chromium complexes and olefin oligomerization catalysts therefrom 陶氏环球技术有限责任公司 2021-07-23 CN disclosed
US-20210129125-A1 PROCESS FOR OLIGOMERIZATION DOW GLOBAL TECHNOLOGIES LLC (US) 2021-05-06 US disclosed
US-10981156-B2 Chromium complex and catalyst therefrom DOW GLOBAL TECHNOLOGIES LLC (US) 2021-04-20 US disclosed
US-10919031-B2 Process for oligomerization DOW GLOBAL TECHNOLOGIES LLC (US) 2021-02-16 US disclosed
US-20200338542-A1 PROCESS FOR OLIGOMERIZATION DOW GLOBAL TECHNOLOGIES LLC (US) 2020-10-29 US disclosed
US-10702861-B2 Process for oligomerization DOW GLOBAL TECHNOLOGIES LLC (US) 2020-07-07 US disclosed
US-20200030783-A1 PROCESS FOR OLIGOMERIZATION DOW GLOBAL TECHNOLOGIES LLC (US) 2020-01-30 US disclosed
US-10376869-B2 Process for oligomerization DOW GLOBAL TECHNOLOGIES LLC (US) 2019-08-13 US disclosed
US-10357764-B2 Phosphacycle compound and process for production thereof DOW GLOBAL TECHNOLOGIES LLC (US) 2019-07-23 US disclosed
US-20190210013-A1 CHROMIUM COMPLEX AND CATALYST THEREFROM DOW GLOBAL TECHNOLOGIES LLC (US) 2019-07-11 US disclosed
US-10207262-B2 Chromium complex and catalyst therefrom DOW GLOBAL TECHNOLOGIES LLC (US) 2019-02-19 US disclosed
US-20180154344-A1 PROCESS FOR OLIGOMERIZATION DOW GLOBAL TECHNOLOGIES LLC (US) 2018-06-07 US disclosed
US-20180071725-A1 CHROMIUM COMPLEX AND CATALYST THEREFROM DOW GLOBAL TECHNOLOGIES LLC (US) 2018-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210129125-A1 PROCESS FOR OLIGOMERIZATION OXER1, NOD1, LIG1 ALDH1A1 4182/4885TSHR 4279/4885KIF11 4338/4885
US-20200338542-A1 PROCESS FOR OLIGOMERIZATION OXER1, NOD1, LIG1 ALDH1A1 4182/4885TSHR 4279/4885KIF11 4338/4885
US-20180071725-A1 CHROMIUM COMPLEX AND CATALYST THEREFROM OXER1, LIG1, PICALM ALDH1A1 4013/4885TSHR 4123/4885KIF11 3182/4885
US-10919031-B2 Process for oligomerization OXER1, NOD1, LIG1 ALDH1A1 4182/4885TSHR 4279/4885KIF11 4338/4885
US-10376869-B2 Process for oligomerization OXER1, NOD1, LIG1 ALDH1A1 4182/4885TSHR 4279/4885KIF11 4338/4885
US-10981156-B2 Chromium complex and catalyst therefrom OXER1, LIG1, PICALM ALDH1A1 4013/4885TSHR 4123/4885KIF11 3182/4885
US-10357764-B2 Phosphacycle compound and process for production thereof OXER1, PPIP5K2, IP6K1 ALDH1A1 4091/4885TSHR 4062/4885KIF11 3779/4885
US-10207262-B2 Chromium complex and catalyst therefrom OXER1, LIG1, PICALM ALDH1A1 4013/4885TSHR 4123/4885KIF11 3182/4885
US-20200030783-A1 PROCESS FOR OLIGOMERIZATION OXER1, NOD1, LIG1 ALDH1A1 4182/4885TSHR 4279/4885KIF11 4338/4885
US-20180154344-A1 PROCESS FOR OLIGOMERIZATION OXER1, NOD1, LIG1 ALDH1A1 4182/4885TSHR 4279/4885KIF11 4338/4885
US-20220176363-A1 PROCESS FOR OLIGOMERIZATION OXER1, NOD1, LIG1 ALDH1A1 4182/4885TSHR 4279/4885KIF11 4338/4885
US-20190210013-A1 CHROMIUM COMPLEX AND CATALYST THEREFROM OXER1, LIG1, PICALM ALDH1A1 4013/4885TSHR 4123/4885KIF11 3182/4885
US-10702861-B2 Process for oligomerization OXER1, NOD1, LIG1 ALDH1A1 4182/4885TSHR 4279/4885KIF11 4338/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.