Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 13/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983970 | 0.90 | SLC6A2 (0.38) | SLC6A4SLC6A2SLC6A3GRM4GPR84 | |
| SCHEMBL19984037 | 0.84 | SLC6A2 (0.34) | SLC6A4SLC6A2SLC6A3GRM4ALDH1A1 | |
| SCHEMBL19983836 | 0.82 | SLC6A2 (0.39) | SLC6A4SLC6A2SLC6A3KCNH2GPR84 | |
| SCHEMBL19984197 | 0.81 | GPR84 (0.49) | SLC6A4SLC6A2SLC6A3KCNH2GPR84 | |
| SCHEMBL19983861 | 0.70 | GPR84 (0.41) | SLC6A4KCNH2GRM4GPR84HTR2A | |
| SCHEMBL19983891 | 0.69 | GPR84 (0.49) | SLC6A4GPR84HTR2A | |
| SCHEMBL19984005 | 0.68 | HTR2A (0.44) | GPR84HTR2AALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL19983772 | 0.68 | GPR84 (0.48) | SLC6A4SLC6A2KCNH2GPR84HTR2A | |
| SCHEMBL19983867 | 0.67 | HTR2C (0.42) | SLC6A4HTR2AALDH1A1 | |
| SCHEMBL19984048 | 0.67 | TDO2 (0.42) | SLC6A4GPR84HTR2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |