Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 8/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.35 |
| ▸ | GOT1 | P17174 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 3/20 | 0.34 |
| ▸ | QPCT | Q16769 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | BCR | P11274 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983841 | 0.90 | SLC6A4 (0.43) | SLC6A2SLC6A4SLC6A3GRM4GPR84 | |
| SCHEMBL19983836 | 0.90 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3MAPK1GPR84 | |
| SCHEMBL19984037 | 0.90 | SLC6A2 (0.34) | SLC6A2SLC6A4SLC6A3GRM4 | |
| SCHEMBL19984030 | 0.71 | GPR84 (0.48) | SLC6A2SLC6A4SLC6A3GPR84 | |
| SCHEMBL19983715 | 0.70 | HTR2A (0.42) | GPR84 | |
| SCHEMBL19984197 | 0.70 | GPR84 (0.49) | SLC6A2SLC6A4SLC6A3GPR84 | |
| SCHEMBL19983772 | 0.69 | GPR84 (0.48) | SLC6A2SLC6A4GPR84 | |
| SCHEMBL19983739 | 0.69 | CHRNB2 (0.50) | SLC6A4GPR84MAPT | |
| SCHEMBL19984249 | 0.69 | TDO2 (0.41) | SLC6A2SLC6A3GPR84 | |
| SCHEMBL19983861 | 0.68 | GPR84 (0.41) | SLC6A4GRM4GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |