Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 2/20 | 0.32 |
| ▸ | IDH1 | O75874 | 15/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983939 | 0.72 | ABL1 (0.37) | ABL1 | |
| SCHEMBL16619188 | 0.71 | LMNA (0.40) | LRRK2FBP1ABL1 | |
| SCHEMBL19984057 | 0.64 | AKR1C3 (0.35) | LRRK2 | |
| SCHEMBL19983885 | 0.63 | FBP1 (0.39) | FBP1ABL1 | |
| SCHEMBL16618640 | 0.61 | LMNA (0.41) | FBP1ABL1 | |
| SCHEMBL19983961 | 0.61 | DHODH (0.37) | — | |
| SCHEMBL19983946 | 0.61 | SLC6A4 (0.38) | FBP1ABL1 | |
| SCHEMBL17971590 | 0.61 | FBP1 (0.47) | FBP1 | |
| SCHEMBL19983775 | 0.60 | EGFR (0.34) | FBP1 | |
| SCHEMBL19983934 | 0.60 | TUBB1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |