Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 17/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984182 | 0.86 | P2RX7 (0.31) | P2RX7 | |
| SCHEMBL19983775 | 0.84 | EGFR (0.34) | P2RX7 | |
| SCHEMBL19983777 | 0.84 | ADRB2 (0.37) | P2RX7 | |
| SCHEMBL19983889 | 0.84 | HTR2A (0.33) | ALDH1A1 | |
| SCHEMBL19983885 | 0.83 | FBP1 (0.39) | P2RX7 | |
| SCHEMBL16626741 | 0.81 | RORC (0.42) | P2RX7 | |
| Hydrochloric Acid SCHEMBL16618714 | 0.81 | RORC (0.42) | P2RX7 | |
| SCHEMBL19983791 | 0.80 | KDR (0.33) | P2RX7 | |
| SCHEMBL19984027 | 0.78 | MAPK14 (0.37) | KMT2A | |
| SCHEMBL19984007 | 0.77 | MAT2A (0.34) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |