Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | FASN | P49327 | 2/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20003154 | 0.79 | RORC (0.39) | GRIN1GRIN2BNPC1RAB9AATM | |
| SCHEMBL20002823 | 0.78 | CCR5 (0.38) | GRIN1GRIN2BNPC1RAB9AATM | |
| SCHEMBL20003191 | 0.77 | RORC (0.41) | GRIN1GRIN2BNPC1RAB9AATM | |
| SCHEMBL20002375 | 0.76 | RORC (0.41) | GRIN1GRIN2BNPC1RAB9AATM | |
| SCHEMBL20003220 | 0.76 | RORC (0.41) | GRIN1GRIN2BNPC1RAB9AATM | |
| SCHEMBL20003026 | 0.73 | RORC (0.47) | GRIN1GRIN2BNPC1RAB9AATM | |
| SCHEMBL20002430 | 0.73 | RORC (0.44) | CCR5KMT2ARORC | |
| SCHEMBL20003152 | 0.73 | RAB9A (0.34) | GRIN1GRIN2BNPC1RAB9AATM | |
| SCHEMBL20002294 | 0.72 | PTPN11 (0.36) | GRIN1GRIN2BCCR5KMT2ADDB1 | |
| SCHEMBL20002719 | 0.72 | HSD11B1 (0.48) | ALDH1A1KMT2AHSD11B1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3092229-B1 | PYRROLIDINYL SULFONE DERIVATIVES AND THEIR USE AS ROR GAMMA MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2018-03-28 | — | — | EP | disclosed |