Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 5/20 | 0.32 |
| ▸ | GPR55 | Q9Y2T6 | 3/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | PRLHR | P49683 | 2/20 | 0.31 |
| ▸ | GPR6 | P46095 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042796 | 0.85 | P2RX7 (0.38) | P2RX7KDM4ETSHRHPGDHSD17B10 | |
| SCHEMBL20042794 | 0.84 | KDM4E (0.50) | P2RX7KDM4EHPGDRECQL | |
| SCHEMBL20042917 | 0.83 | P2RX7 (0.39) | P2RX7CHRM2CHRM4KDM4ELMNA | |
| SCHEMBL20042911 | 0.82 | P2RX7 (0.39) | P2RX7CHRM2CHRM4KDM4EHPGD | |
| SCHEMBL20042829 | 0.82 | P2RX7 (0.41) | P2RX7KDM4ETSHRHPGDCASP1 | |
| SCHEMBL20042743 | 0.82 | P2RX7 (0.40) | P2RX7CHRM4KDM4ETSHRHPGD | |
| SCHEMBL20042756 | 0.81 | P2RX7 (0.38) | P2RX7KDM4ETSHRLMNANR4A1 | |
| SCHEMBL20042671 | 0.81 | P2RX7 (0.45) | P2RX7TSHRHPGDSMN1; SMN2GBA1 | |
| SCHEMBL20042836 | 0.81 | P2RX7 (0.43) | P2RX7TSHRHPGDSMN1; SMN2GBA1 | |
| SCHEMBL20042689 | 0.80 | P2RX7 (0.39) | P2RX7CASP1CASP7HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |