Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 11/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042872 | 0.89 | P2RX7 (0.44) | P2RX7PROKR1CHRM4GBA1CNR1 | |
| SCHEMBL20042689 | 0.88 | P2RX7 (0.39) | P2RX7PROKR1GBA1CNR2CASP1 | |
| SCHEMBL20042829 | 0.88 | P2RX7 (0.41) | P2RX7GBA1HPGDKDM4ECNR1 | |
| SCHEMBL20042839 | 0.85 | P2RX7 (0.45) | P2RX7GBA1HPGDKDM4ECNR1 | |
| SCHEMBL20042817 | 0.85 | PKM (0.44) | P2RX7GBA1HPGDKDM4E | |
| SCHEMBL20042854 | 0.85 | GRM5 (0.42) | P2RX7PROKR1GBA1HPGDKDM4E | |
| SCHEMBL20042671 | 0.85 | P2RX7 (0.45) | P2RX7GBA1HPGDCNR1CNR2 | |
| SCHEMBL20042755 | 0.84 | GRM5 (0.43) | P2RX7GBA1HPGDKDM4ETSHR | |
| SCHEMBL20042873 | 0.84 | P2RX7 (0.38) | P2RX7GBA1HPGDKDM4ECNR1 | |
| SCHEMBL20042668 | 0.84 | HPGD (0.51) | P2RX7GBA1HPGDKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |