Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PROKR1 | Q8TCW9 | 7/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | BCR | P11274 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042872 | 0.87 | P2RX7 (0.44) | PROKR1CHRM4P2RX7HSD17B10LMNA | |
| SCHEMBL20043089 | 0.84 | P2RX7 (0.52) | PROKR1CHRM2CHRM4P2RX7HSD17B10 | |
| SCHEMBL20042701 | 0.84 | PROKR1 (0.47) | PROKR1CHRM4P2RX7HSD17B10LMNA | |
| SCHEMBL20042668 | 0.83 | HPGD (0.51) | P2RX7HPGDKDM4ELMNASMN1; SMN2 | |
| SCHEMBL20042817 | 0.82 | PKM (0.44) | P2RX7HPGDKDM4ELMNAALDH1A1 | |
| SCHEMBL20042680 | 0.82 | GPR6 (0.44) | P2RX7HPGDTSHRKDM4ECASP1 | |
| SCHEMBL20042671 | 0.82 | P2RX7 (0.45) | P2RX7HPGDTSHRSMN1; SMN2CNR1 | |
| SCHEMBL31614823 | 0.81 | CHRM4 (0.52) | PROKR1CHRM2CHRM4SCN10ATSHR | |
| SCHEMBL20042776 | 0.81 | P2RX7 (0.41) | P2RX7TSHRKDM4ELMNANR4A1 | |
| SCHEMBL20042700 | 0.80 | TSHR (0.40) | P2RX7HPGDTSHRKDM4ECASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |